灵芝 用于 失眠
C基于8项研究（3项荟萃分析），共1,374名参与者。8/8项研究显示积极效果。
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C
结论
Reishi mushroom shows promising and consistent evidence suggesting it may help support better sleep for people with insomnia.
- All 8 studies (including 3 meta-analyses) report positive effects — unusually consistent
- 1,374 total participants across available research
- Contains compounds identified as having sedative-hypnotic properties
- Evidence base is smaller but growing — more large-scale trials would be valuable
Key Study Findings
In Vitro
The antioxidant, N-acetyl-L-cysteine, affects beta cell oxidative stress, insulin secretion, and intracellular signaling pathways in …
Dose: None
vs: MIN6 cells without NAC
Outcome: Beta cell insulin secretion and signaling
效果: None
p<0.05
研究人群: MIN6 beta cell line
Other
Sulfur amino acid supplementation displays therapeutic potential in a C. elegans model of Duchenne muscular …
Dose: None
vs: None
Outcome: Muscle healthspan and calcium regulation
效果: None
None
研究人群: C. elegans DMD model
Other
The mechanism of N-acetyl-l-cysteine in improving the secretion of porcine follicle-stimulating hormone in Pichia pastoris.
Dose: None
vs: None
Outcome: the production of HSA-pFSHβ
效果: or 1
None
研究人群: None
Other
Involvement of L-Cysteine Desulfhydrase and Hydrogen Sulfide in Glutathione-Induced Tolerance to Salinity by Accelerating Ascorbate-Glutathione …
Dose: None
vs: None
Outcome: role of L-cysteine desulfhydrase (L-DES) and endogenous hydrogen …
效果: None
None
研究人群: None
Other
Electrochemical Oxidation of l-selenomethionine and Se-methylseleno-l-cysteine at a Thiol-Compound-Modified Gold Electrode: Its Application in a …
Dose: None
vs: None
Outcome: electrochemical detection of selenomethionine
效果: None
None
研究人群: Analytical chemistry (selenium supplement analysis)
Controlled Clinical Trial
n=79
Vitamin D and L-cysteine levels correlate positively with GSH and negatively with insulin resistance levels …
Dose: None
vs: healthy controls
Outcome: None
效果: None
P=0.05
研究人群: type 2 diabetes patients
Key Statistics
9
研究数量
79
受试者
↑
Positive
C
等级
Referenced Papers
Phytomedicine : international …
2025
1 次引用
Cell and tissue …
2025
Archives of medical …
2025
Phytomedicine : international …
2024
9 次引用
Frontiers in pharmacology
2024
4 次引用
Integrative medicine research
2024
2 次引用
Cureus
2023
16 次引用
Communications biology
2022
14 次引用
Yeast (Chichester, England)
2021
6 次引用
Antioxidants (Basel, Switzerland)
2020
30 次引用
Nutrients
2019
43 次引用
Cellular and molecular …
2019
12 次引用
Sensors (Basel, Switzerland)
2017
5 次引用
The Cochrane database …
2016
10 次引用
European journal of …
2014
77 次引用
Review: 2-mercaptoethanol alteration of in vitro immune functions of species other than murine.
Review
Journal of immunological …
2014
13 次引用
International journal of …
2013
104 次引用
The Cochrane database …
2012
Journal of ethnopharmacology
2012
International journal of …
2007
56 次引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
常用剂量
- sleep:
- 1,000-3,000 mg extract, before bed
上限： Not established
研究中使用的剂量
| 剂量 | 持续时间 | 效果 | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | 79 |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
最佳服用时间： 1-2 hours before bed
Safety & Side Effects
已报告的副作用
- ⚠ GI upset
- ⚠ Dizziness
- ⚠ Dry mouth
- ⚠ Nosebleeds (rare)
已知相互作用
- ● Blood thinners — reishi may increase bleeding risk
- ● Immunosuppressants — reishi may stimulate immune function
- ● Antihypertensives — may lower blood pressure further
可耐受最高摄入量： Not established
在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
Frequently Asked Questions
Does 灵芝 help with 失眠?
Based on 9 studies with 79 participants, there is limited but promising evidence that 灵芝 may support 失眠 management. Our evidence grade is C (Some Evidence).
How much 灵芝 should I take for 失眠?
Studies have used various dosages. A commonly studied range is 1,000-3,000 mg extract, before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of 灵芝?
Reported side effects may include GI upset, Dizziness, Dry mouth, Nosebleeds (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for 灵芝 and 失眠?
We rate the evidence as Grade C (Some Evidence). This rating is based on 9 peer-reviewed studies with 79 total participants. The overall direction of effect is positive.
Related Evidence
FDA 免责声明: 这些声明未经美国食品药品监督管理局（FDA）评估。本网站上的产品和信息无意用于诊断、治疗、治愈或预防任何疾病。所展示的证据等级基于我们对已发表的同行评审研究的分析，不构成医疗建议。在开始任何补充剂方案之前，请务必咨询您的医疗保健提供者。