Reishi Mushroom के लिए अनिद्रा
C साक्ष्य की तुलना करें छोटे अध्ययनों से सीमित साक्ष्य उपलब्ध हैं, लेकिन कुछ सकारात्मक संकेत मौजूद हैं।8 अध्ययनों (3 meta-analyses) पर आधारित, में कुल 1,374 प्रतिभागियों के साथ। 8/8 अध्ययन सकारात्मक प्रभाव दिखाते हैं।
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C
निष्कर्ष
Reishi mushroom shows promising and consistent evidence suggesting it may help support better sleep for people with insomnia.
- All 8 studies (including 3 meta-analyses) report positive effects — unusually consistent
- 1,374 total participants across available research
- Contains compounds identified as having sedative-hypnotic properties
- Evidence base is smaller but growing — more large-scale trials would be valuable
Key Study Findings
In Vitro
The antioxidant, N-acetyl-L-cysteine, affects beta cell oxidative stress, insulin secretion, and intracellular signaling pathways in …
Dose: None
बनाम: MIN6 cells without NAC
Outcome: Beta cell insulin secretion and signaling
प्रभाव: None
p<0.05
जनसंख्या: MIN6 beta cell line
Other
Sulfur amino acid supplementation displays therapeutic potential in a C. elegans model of Duchenne muscular …
Dose: None
बनाम: None
Outcome: Muscle healthspan and calcium regulation
प्रभाव: None
None
जनसंख्या: C. elegans DMD model
Other
The mechanism of N-acetyl-l-cysteine in improving the secretion of porcine follicle-stimulating hormone in Pichia pastoris.
Dose: None
बनाम: None
Outcome: the production of HSA-pFSHβ
प्रभाव: or 1
None
जनसंख्या: None
Other
Involvement of L-Cysteine Desulfhydrase and Hydrogen Sulfide in Glutathione-Induced Tolerance to Salinity by Accelerating Ascorbate-Glutathione …
Dose: None
बनाम: None
Outcome: role of L-cysteine desulfhydrase (L-DES) and endogenous hydrogen …
प्रभाव: None
None
जनसंख्या: None
Other
Electrochemical Oxidation of l-selenomethionine and Se-methylseleno-l-cysteine at a Thiol-Compound-Modified Gold Electrode: Its Application in a …
Dose: None
बनाम: None
Outcome: electrochemical detection of selenomethionine
प्रभाव: None
None
जनसंख्या: Analytical chemistry (selenium supplement analysis)
Controlled Clinical Trial
n=79
Vitamin D and L-cysteine levels correlate positively with GSH and negatively with insulin resistance levels …
Dose: None
बनाम: healthy controls
Outcome: None
प्रभाव: None
P=0.05
जनसंख्या: type 2 diabetes patients
Key Statistics
9
अध्ययन
79
प्रतिभागी
↑
Positive
C
ग्रेड
Referenced Papers
Phytomedicine : international …
2025
1 उद्धरण
Cell and tissue …
2025
Archives of medical …
2025
Phytomedicine : international …
2024
9 उद्धरण
Frontiers in pharmacology
2024
4 उद्धरण
Integrative medicine research
2024
2 उद्धरण
Cureus
2023
16 उद्धरण
Communications biology
2022
14 उद्धरण
Yeast (Chichester, England)
2021
6 उद्धरण
Antioxidants (Basel, Switzerland)
2020
30 उद्धरण
Nutrients
2019
43 उद्धरण
Cellular and molecular …
2019
12 उद्धरण
Sensors (Basel, Switzerland)
2017
5 उद्धरण
The Cochrane database …
2016
10 उद्धरण
European journal of …
2014
77 उद्धरण
Review: 2-mercaptoethanol alteration of in vitro immune functions of species other than murine.
Review
Journal of immunological …
2014
13 उद्धरण
International journal of …
2013
104 उद्धरण
The Cochrane database …
2012
Journal of ethnopharmacology
2012
International journal of …
2007
56 उद्धरण
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
सामान्य रूप से उपयोग की जाने वाली खुराकें
- sleep:
- 1,000-3,000 mg extract, before bed
अधिकतम सीमा: Not established
अनुसंधान में अध्ययन की गई खुराकें
| खुराक | अवधि | प्रभाव | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | 79 |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
सेवन का सर्वोत्तम समय: 1-2 hours before bed
Safety & Side Effects
रिपोर्ट किए गए दुष्प्रभाव
- ⚠ GI upset
- ⚠ Dizziness
- ⚠ Dry mouth
- ⚠ Nosebleeds (rare)
ज्ञात अंतःक्रियाएँ
- ● Blood thinners — reishi may increase bleeding risk
- ● Immunosuppressants — reishi may stimulate immune function
- ● Antihypertensives — may lower blood pressure further
सहनीय अधिकतम सेवन: Not established
कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।
Frequently Asked Questions
Does Reishi Mushroom help with अनिद्रा?
Based on 9 studies with 79 participants, there is limited but promising evidence that Reishi Mushroom may support अनिद्रा management. Our evidence grade is C (Some Evidence).
How much Reishi Mushroom should I take for अनिद्रा?
Studies have used various dosages. A commonly studied range is 1,000-3,000 mg extract, before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Reishi Mushroom?
Reported side effects may include GI upset, Dizziness, Dry mouth, Nosebleeds (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Reishi Mushroom and अनिद्रा?
We rate the evidence as Grade C (Some Evidence). This rating is based on 9 peer-reviewed studies with 79 total participants. The overall direction of effect is positive.
Related Evidence
इसके लिए अन्य सामग्री अनिद्रा
References
- [1] Wei Chen et al.. Phytomedicine. 2025. Sedative-hypnotic effects of an herbal formulation comprising Ganoderma, Gastrodiae Rhizoma, and Chrysanthemi Flos in mice. doi:10.1016/j.phymed.2025.157374 PubMed
- [2] Meg Schuurman et al.. Cell Tissue Res. 2025. The antioxidant, N-acetyl-L-cysteine, affects beta cell oxidative stress, insulin secretion, and intracellular signaling pathways in MIN6 cells. doi:10.1007/s00441-025-04020-x PubMed
- [3] Xu Wang et al.. Arch Med Sci. 2025. Gut microbiota and insomnia: Mendelian randomization and network pharmacology to predict potential intervention with traditional Chinese medicine. doi:10.5114/aoms/207509 PubMed
- [4] Wei Chen et al.. Phytomedicine. 2024. Identification of sedative-hypnotic compounds shared by five medicinal Polyporales mushrooms using UPLC-Q-TOF-MS/MS-based untargeted metabolomics. doi:10.1016/j.phymed.2024.155355 PubMed
- [5] Yu Qin et al.. Front Pharmacol. 2024. Ganoderma lucidum spore extract improves sleep disturbances in a rat model of sporadic Alzheimer's disease. doi:10.3389/fphar.2024.1390294 PubMed
- [6] Xiaotong Li et al.. Integr Med Res. 2024. Symptom improvements and adverse effects with Reishi mushroom use: A Cross-Sectional survey of cancer patients. doi:10.1016/j.imr.2024.101089 PubMed
- [7] Nguyen Huu Lac Thuy et al.. Cureus. 2023. Pharmacological Activities and Safety of Ganoderma lucidum Spores: A Systematic Review. doi:10.7759/cureus.44574 PubMed
- [8] Rebecca A Ellwood et al.. Commun Biol. 2022. Sulfur amino acid supplementation displays therapeutic potential in a C. elegans model of Duchenne muscular dystrophy. doi:10.1038/s42003-022-04212-z PubMed
- [9] Gang Luo et al.. Yeast. 2021. The mechanism of N-acetyl-l-cysteine in improving the secretion of porcine follicle-stimulating hormone in Pichia pastoris. doi:10.1002/yea.3668 PubMed
- [10] Cengiz Kaya et al.. Antioxidants (Basel). 2020. Involvement of L-Cysteine Desulfhydrase and Hydrogen Sulfide in Glutathione-Induced Tolerance to Salinity by Accelerating Ascorbate-Glutathione Cycle and Glyoxalase System in … doi:10.3390/antiox9070603 PubMed
- [11] Feiya Sheng et al.. Nutrients. 2019. Deacetyl Ganoderic Acid F Inhibits LPS-Induced Neural Inflammation via NF-κB Pathway Both In Vitro and In Vivo. doi:10.3390/nu12010085 PubMed
- [12] Xia Feng et al.. Cell Mol Biol (Noisy-le-grand). 2019. Anti-inflammatory, anti-nociceptive and sedative-hypnotic activities of lucidone D extracted from Ganoderma lucidum. PubMed
- [13] Lai-Hao Wang et al.. Sensors (Basel). 2017. Electrochemical Oxidation of l-selenomethionine and Se-methylseleno-l-cysteine at a Thiol-Compound-Modified Gold Electrode: Its Application in a Flow-Through Voltammetric Sensor. doi:10.3390/s17020383 PubMed
- [14] Xingzhong Jin et al.. Cochrane Database Syst Rev. 2016. Ganoderma lucidum (Reishi mushroom) for cancer treatment. doi:10.1002/14651858.CD007731.pub3 PubMed
- [15] S K Jain et al.. Eur J Clin Nutr. 2014. Vitamin D and L-cysteine levels correlate positively with GSH and negatively with insulin resistance levels in the blood of type … doi:10.1038/ejcn.2014.114 PubMed
- [16] Robert E Click. J Immunol Methods. 2014. Review: 2-mercaptoethanol alteration of in vitro immune functions of species other than murine. doi:10.1016/j.jim.2013.11.007 PubMed
- [17] Priya Batra et al.. Int J Med Mushrooms. 2013. Probing Lingzhi or Reishi medicinal mushroom Ganoderma lucidum (higher Basidiomycetes): a bitter mushroom with amazing health benefits. doi:10.1615/intjmedmushr.v15.i2.20 PubMed
- [18] Xingzhong Jin et al.. Cochrane Database Syst Rev. 2012. Ganoderma lucidum (Reishi mushroom) for cancer treatment. doi:10.1002/14651858.CD007731.pub2 PubMed
- [19] Xiang-Yu Cui et al.. J Ethnopharmacol. 2012. Extract of Ganoderma lucidum prolongs sleep time in rats. doi:10.1016/j.jep.2011.12.020 PubMed
- [20] Willem I de Boer et al.. Int J Chron Obstruct Pulmon Dis. 2007. Future therapeutic treatment of COPD: struggle between oxidants and cytokines. PubMed
FDA अस्वीकरण: इन कथनों का Food and Drug Administration द्वारा मूल्यांकन नहीं किया गया है। इस वेबसाइट पर उत्पादों और जानकारी का उद्देश्य किसी बीमारी का निदान, उपचार, इलाज या रोकथाम नहीं है। प्रस्तुत साक्ष्य ग्रेड प्रकाशित पीयर-रिव्यूड अनुसंधान के हमारे विश्लेषण पर आधारित हैं और चिकित्सा सलाह नहीं हैं। कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।