فطر الريشي لـ الأرق
C الأدلة أدلة محدودة من دراسات صغيرة، غير أن ثمة بعض الإشارات الإيجابية.بناءً على 8 دراسة (3 meta-analyses) بمشاركة 1,374 مشاركًا إجمالاً. 8/8 دراسة تُظهر تأثيرات إيجابية.
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C
الخلاصة
Reishi mushroom shows promising and consistent evidence suggesting it may help support better sleep for people with insomnia.
- All 8 studies (including 3 meta-analyses) report positive effects — unusually consistent
- 1,374 total participants across available research
- Contains compounds identified as having sedative-hypnotic properties
- Evidence base is smaller but growing — more large-scale trials would be valuable
Key Study Findings
In Vitro
The antioxidant, N-acetyl-L-cysteine, affects beta cell oxidative stress, insulin secretion, and intracellular signaling pathways in …
Dose: None
مقابل: MIN6 cells without NAC
Outcome: Beta cell insulin secretion and signaling
التأثير: None
p<0.05
المجتمع المدروس: MIN6 beta cell line
Other
Sulfur amino acid supplementation displays therapeutic potential in a C. elegans model of Duchenne muscular …
Dose: None
مقابل: None
Outcome: Muscle healthspan and calcium regulation
التأثير: None
None
المجتمع المدروس: C. elegans DMD model
Other
The mechanism of N-acetyl-l-cysteine in improving the secretion of porcine follicle-stimulating hormone in Pichia pastoris.
Dose: None
مقابل: None
Outcome: the production of HSA-pFSHβ
التأثير: or 1
None
المجتمع المدروس: None
Other
Involvement of L-Cysteine Desulfhydrase and Hydrogen Sulfide in Glutathione-Induced Tolerance to Salinity by Accelerating Ascorbate-Glutathione …
Dose: None
مقابل: None
Outcome: role of L-cysteine desulfhydrase (L-DES) and endogenous hydrogen …
التأثير: None
None
المجتمع المدروس: None
Other
Electrochemical Oxidation of l-selenomethionine and Se-methylseleno-l-cysteine at a Thiol-Compound-Modified Gold Electrode: Its Application in a …
Dose: None
مقابل: None
Outcome: electrochemical detection of selenomethionine
التأثير: None
None
المجتمع المدروس: Analytical chemistry (selenium supplement analysis)
Controlled Clinical Trial
n=79
Vitamin D and L-cysteine levels correlate positively with GSH and negatively with insulin resistance levels …
Dose: None
مقابل: healthy controls
Outcome: None
التأثير: None
P=0.05
المجتمع المدروس: type 2 diabetes patients
Key Statistics
9
الدراسات
79
المشاركون
↑
Positive
C
التقييم
Referenced Papers
Phytomedicine : international …
2025
1 اقتباسات
Cell and tissue …
2025
Archives of medical …
2025
Phytomedicine : international …
2024
9 اقتباسات
Frontiers in pharmacology
2024
4 اقتباسات
Integrative medicine research
2024
2 اقتباسات
Cureus
2023
16 اقتباسات
Communications biology
2022
14 اقتباسات
Yeast (Chichester, England)
2021
6 اقتباسات
Antioxidants (Basel, Switzerland)
2020
30 اقتباسات
Nutrients
2019
43 اقتباسات
Cellular and molecular …
2019
12 اقتباسات
Sensors (Basel, Switzerland)
2017
5 اقتباسات
The Cochrane database …
2016
10 اقتباسات
European journal of …
2014
77 اقتباسات
Review: 2-mercaptoethanol alteration of in vitro immune functions of species other than murine.
Review
Journal of immunological …
2014
13 اقتباسات
International journal of …
2013
104 اقتباسات
The Cochrane database …
2012
Journal of ethnopharmacology
2012
International journal of …
2007
56 اقتباسات
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
الجرعات الشائعة
- sleep:
- 1,000-3,000 mg extract, before bed
الحد الأعلى: Not established
الجرعات المدروسة في الأبحاث
| الجرعة | المدة | التأثير | ن |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | 79 |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
أفضل وقت للتناول: 1-2 hours before bed
Safety & Side Effects
الآثار الجانبية المُبلّغ عنها
- ⚠ GI upset
- ⚠ Dizziness
- ⚠ Dry mouth
- ⚠ Nosebleeds (rare)
التفاعلات المعروفة
- ● Blood thinners — reishi may increase bleeding risk
- ● Immunosuppressants — reishi may stimulate immune function
- ● Antihypertensives — may lower blood pressure further
الحد الأقصى المسموح به: Not established
استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.
Frequently Asked Questions
Does فطر الريشي help with الأرق?
Based on 9 studies with 79 participants, there is limited but promising evidence that فطر الريشي may support الأرق management. Our evidence grade is C (Some Evidence).
How much فطر الريشي should I take for الأرق?
Studies have used various dosages. A commonly studied range is 1,000-3,000 mg extract, before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of فطر الريشي?
Reported side effects may include GI upset, Dizziness, Dry mouth, Nosebleeds (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for فطر الريشي and الأرق?
We rate the evidence as Grade C (Some Evidence). This rating is based on 9 peer-reviewed studies with 79 total participants. The overall direction of effect is positive.
Related Evidence
مكونات أخرى لـ الأرق
References
- [1] Wei Chen et al.. Phytomedicine. 2025. Sedative-hypnotic effects of an herbal formulation comprising Ganoderma, Gastrodiae Rhizoma, and Chrysanthemi Flos in mice. doi:10.1016/j.phymed.2025.157374 PubMed
- [2] Meg Schuurman et al.. Cell Tissue Res. 2025. The antioxidant, N-acetyl-L-cysteine, affects beta cell oxidative stress, insulin secretion, and intracellular signaling pathways in MIN6 cells. doi:10.1007/s00441-025-04020-x PubMed
- [3] Xu Wang et al.. Arch Med Sci. 2025. Gut microbiota and insomnia: Mendelian randomization and network pharmacology to predict potential intervention with traditional Chinese medicine. doi:10.5114/aoms/207509 PubMed
- [4] Wei Chen et al.. Phytomedicine. 2024. Identification of sedative-hypnotic compounds shared by five medicinal Polyporales mushrooms using UPLC-Q-TOF-MS/MS-based untargeted metabolomics. doi:10.1016/j.phymed.2024.155355 PubMed
- [5] Yu Qin et al.. Front Pharmacol. 2024. Ganoderma lucidum spore extract improves sleep disturbances in a rat model of sporadic Alzheimer's disease. doi:10.3389/fphar.2024.1390294 PubMed
- [6] Xiaotong Li et al.. Integr Med Res. 2024. Symptom improvements and adverse effects with Reishi mushroom use: A Cross-Sectional survey of cancer patients. doi:10.1016/j.imr.2024.101089 PubMed
- [7] Nguyen Huu Lac Thuy et al.. Cureus. 2023. Pharmacological Activities and Safety of Ganoderma lucidum Spores: A Systematic Review. doi:10.7759/cureus.44574 PubMed
- [8] Rebecca A Ellwood et al.. Commun Biol. 2022. Sulfur amino acid supplementation displays therapeutic potential in a C. elegans model of Duchenne muscular dystrophy. doi:10.1038/s42003-022-04212-z PubMed
- [9] Gang Luo et al.. Yeast. 2021. The mechanism of N-acetyl-l-cysteine in improving the secretion of porcine follicle-stimulating hormone in Pichia pastoris. doi:10.1002/yea.3668 PubMed
- [10] Cengiz Kaya et al.. Antioxidants (Basel). 2020. Involvement of L-Cysteine Desulfhydrase and Hydrogen Sulfide in Glutathione-Induced Tolerance to Salinity by Accelerating Ascorbate-Glutathione Cycle and Glyoxalase System in … doi:10.3390/antiox9070603 PubMed
- [11] Feiya Sheng et al.. Nutrients. 2019. Deacetyl Ganoderic Acid F Inhibits LPS-Induced Neural Inflammation via NF-κB Pathway Both In Vitro and In Vivo. doi:10.3390/nu12010085 PubMed
- [12] Xia Feng et al.. Cell Mol Biol (Noisy-le-grand). 2019. Anti-inflammatory, anti-nociceptive and sedative-hypnotic activities of lucidone D extracted from Ganoderma lucidum. PubMed
- [13] Lai-Hao Wang et al.. Sensors (Basel). 2017. Electrochemical Oxidation of l-selenomethionine and Se-methylseleno-l-cysteine at a Thiol-Compound-Modified Gold Electrode: Its Application in a Flow-Through Voltammetric Sensor. doi:10.3390/s17020383 PubMed
- [14] Xingzhong Jin et al.. Cochrane Database Syst Rev. 2016. Ganoderma lucidum (Reishi mushroom) for cancer treatment. doi:10.1002/14651858.CD007731.pub3 PubMed
- [15] S K Jain et al.. Eur J Clin Nutr. 2014. Vitamin D and L-cysteine levels correlate positively with GSH and negatively with insulin resistance levels in the blood of type … doi:10.1038/ejcn.2014.114 PubMed
- [16] Robert E Click. J Immunol Methods. 2014. Review: 2-mercaptoethanol alteration of in vitro immune functions of species other than murine. doi:10.1016/j.jim.2013.11.007 PubMed
- [17] Priya Batra et al.. Int J Med Mushrooms. 2013. Probing Lingzhi or Reishi medicinal mushroom Ganoderma lucidum (higher Basidiomycetes): a bitter mushroom with amazing health benefits. doi:10.1615/intjmedmushr.v15.i2.20 PubMed
- [18] Xingzhong Jin et al.. Cochrane Database Syst Rev. 2012. Ganoderma lucidum (Reishi mushroom) for cancer treatment. doi:10.1002/14651858.CD007731.pub2 PubMed
- [19] Xiang-Yu Cui et al.. J Ethnopharmacol. 2012. Extract of Ganoderma lucidum prolongs sleep time in rats. doi:10.1016/j.jep.2011.12.020 PubMed
- [20] Willem I de Boer et al.. Int J Chron Obstruct Pulmon Dis. 2007. Future therapeutic treatment of COPD: struggle between oxidants and cytokines. PubMed
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