霊芝 ： 不眠症
C合計1,374名の参加者を対象とした8件の研究（メタアナリシス3件を含む）に基づく。8件中8件の研究で肯定的な効果が示されている。
<\/script>\n`;
},
get iframeSnippet() {
const domain = 'sleepcited.com';
const params = 'ingredient\u003Dreishi\u002Dmushroom\u0026condition\u003Dinsomnia';
return ``;
},
get activeSnippet() {
return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet;
},
copySnippet() {
navigator.clipboard.writeText(this.activeSnippet).then(() => {
this.copied = true;
setTimeout(() => { this.copied = false; }, 2000);
});
}
}"
@keydown.escape.window="open = false"
@click.outside="open = false">
C
結論
Reishi mushroom shows promising and consistent evidence suggesting it may help support better sleep for people with insomnia.
- All 8 studies (including 3 meta-analyses) report positive effects — unusually consistent
- 1,374 total participants across available research
- Contains compounds identified as having sedative-hypnotic properties
- Evidence base is smaller but growing — more large-scale trials would be valuable
Key Study Findings
In Vitro
The antioxidant, N-acetyl-L-cysteine, affects beta cell oxidative stress, insulin secretion, and intracellular signaling pathways in …
Dose: None
vs: MIN6 cells without NAC
Outcome: Beta cell insulin secretion and signaling
効果: None
p<0.05
対象集団: MIN6 beta cell line
Other
Sulfur amino acid supplementation displays therapeutic potential in a C. elegans model of Duchenne muscular …
Dose: None
vs: None
Outcome: Muscle healthspan and calcium regulation
効果: None
None
対象集団: C. elegans DMD model
Other
The mechanism of N-acetyl-l-cysteine in improving the secretion of porcine follicle-stimulating hormone in Pichia pastoris.
Dose: None
vs: None
Outcome: the production of HSA-pFSHβ
効果: or 1
None
対象集団: None
Other
Involvement of L-Cysteine Desulfhydrase and Hydrogen Sulfide in Glutathione-Induced Tolerance to Salinity by Accelerating Ascorbate-Glutathione …
Dose: None
vs: None
Outcome: role of L-cysteine desulfhydrase (L-DES) and endogenous hydrogen …
効果: None
None
対象集団: None
Other
Electrochemical Oxidation of l-selenomethionine and Se-methylseleno-l-cysteine at a Thiol-Compound-Modified Gold Electrode: Its Application in a …
Dose: None
vs: None
Outcome: electrochemical detection of selenomethionine
効果: None
None
対象集団: Analytical chemistry (selenium supplement analysis)
Controlled Clinical Trial
n=79
Vitamin D and L-cysteine levels correlate positively with GSH and negatively with insulin resistance levels …
Dose: None
vs: healthy controls
Outcome: None
効果: None
P=0.05
対象集団: type 2 diabetes patients
Key Statistics
9
研究数
79
参加者数
↑
Positive
C
グレード
Referenced Papers
Phytomedicine : international …
2025
1 件の引用
Cell and tissue …
2025
Archives of medical …
2025
Phytomedicine : international …
2024
9 件の引用
Frontiers in pharmacology
2024
4 件の引用
Integrative medicine research
2024
2 件の引用
Cureus
2023
16 件の引用
Communications biology
2022
14 件の引用
Yeast (Chichester, England)
2021
6 件の引用
Antioxidants (Basel, Switzerland)
2020
30 件の引用
Nutrients
2019
43 件の引用
Cellular and molecular …
2019
12 件の引用
Sensors (Basel, Switzerland)
2017
5 件の引用
The Cochrane database …
2016
10 件の引用
European journal of …
2014
77 件の引用
Review: 2-mercaptoethanol alteration of in vitro immune functions of species other than murine.
Review
Journal of immunological …
2014
13 件の引用
International journal of …
2013
104 件の引用
The Cochrane database …
2012
Journal of ethnopharmacology
2012
International journal of …
2007
56 件の引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
一般的な使用量
- sleep:
- 1,000-3,000 mg extract, before bed
上限量： Not established
研究で検討された用量
| 用量 | 期間 | 効果 | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | 79 |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
推奨摂取タイミング： 1-2 hours before bed
Safety & Side Effects
報告されている副作用
- ⚠ GI upset
- ⚠ Dizziness
- ⚠ Dry mouth
- ⚠ Nosebleeds (rare)
既知の相互作用
- ● Blood thinners — reishi may increase bleeding risk
- ● Immunosuppressants — reishi may stimulate immune function
- ● Antihypertensives — may lower blood pressure further
耐容上限摂取量： Not established
サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
Frequently Asked Questions
Does 霊芝 help with 不眠症?
Based on 9 studies with 79 participants, there is limited but promising evidence that 霊芝 may support 不眠症 management. Our evidence grade is C (Some Evidence).
How much 霊芝 should I take for 不眠症?
Studies have used various dosages. A commonly studied range is 1,000-3,000 mg extract, before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of 霊芝?
Reported side effects may include GI upset, Dizziness, Dry mouth, Nosebleeds (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for 霊芝 and 不眠症?
We rate the evidence as Grade C (Some Evidence). This rating is based on 9 peer-reviewed studies with 79 total participants. The overall direction of effect is positive.
Related Evidence
FDAに関する免責事項: これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。