Vitamin D untuk Insomnia

Berdasarkan 53 studi (3 meta-analyses, 1 RCT) dengan 685,942 peserta secara total. Hasil bervariasi di antara studi-studi tersebut.

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Kesimpulan

The evidence on vitamin D for insomnia is mixed — low vitamin D levels are associated with poor sleep, but taking vitamin D supplements does not consistently improve insomnia symptoms.

53 studies with 685,942 participants, though mostly from observational research
Low vitamin D levels are associated with poor sleep in population studies
Supplementation results are inconsistent — not a reliable standalone sleep aid
May be most relevant for people who are vitamin D deficient

Key Study Findings

review

Vitamin D and Sleep Disorders.

Dose: None vs: Placebo Efek: None None

review

Top studies of 2024 relevant to primary care: From the PEER team.

Dose: None vs: Placebo Efek: None None

review

Nutritional Supplements for Healthy Aging: A Critical Analysis Review.

Dose: None vs: Placebo Efek: None None

Mendelian randomization

Genetically Supported Causality Between Micronutrients and Sleep Behaviors: A Two-Sample Mendelian Randomization Study.

Dose: None vs: Placebo Efek: Folate vs chronotype OR 1.09 (95% CI 1.01-1.17); Vitamin B6 vs chronotype OR 0.91 (95% CI 0.86-0.96) Folate p=0.02; Vitamin B6 p=1.

review

[Nutrition in improving sleep quality and fighting insomnia].

Dose: tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral vs: Placebo Efek: None None

systematic review and meta-analysis

Causal factors for migraine in Mendelian randomization studies: a systematic review and meta-analysis.

Dose: None vs: Placebo Efek: None None

Key Statistics

Studi

685966

Peserta

↔

Mixed

Peringkat

Referenced Papers

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Vitamin D and Sleep Disorders. Review

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Novel Insights into Somatic Comorbidities in Children and Adolescents Across Psychiatric Diagnoses: An Explorative Study. Other

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Nutritional Supplements for Healthy Aging: A Critical Analysis Review. Review

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Vitamin D deficiency and its potential associations on the health status of older patients with chronic obstructive pulmonary disease in … Other

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Loneliness, insomnia symptoms, social jetlag, and vitamin D deficiency in relation to mental health problems in Japanese female university students: … Other

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Causal factors for migraine in Mendelian randomization studies: a systematic review and meta-analysis. Systematic Review

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The synergistic interaction of vitamin D deficiency and insomnia on dizziness-related handicap in patients with benign paroxysmal positional vertigo. Other

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Causal relations of trace elements and nutrients with insomnia: A Mendelian randomization study. Other

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Corrigendum: The roles of serum vitamin D and tobacco smoke exposure in insomnia: a cross-sectional study of adults in the … Other

Frontiers in nutrition 2025

Beyond bone health: mental and sleep health consequences of vitamin D deficiency in emerging adulthood-findings from a large-scale university study. Other

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Genetically Supported Causality Between Micronutrients and Sleep Behaviors: A Two-Sample Mendelian Randomization Study. Other

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[Advances in Mendelian randomization studies on autism spectrum disorder]. Review

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Commentary: The roles of serum vitamin D and tobacco smoke exposure in insomnia: a cross-sectional study of adults in the … Other

Frontiers in nutrition 2024

Depression and lifestyle: Focusing on nutrition, exercise, and their possible relevance to molecular mechanisms. Meta-Analysis

Psychiatry and clinical … 2023 67 sitasi

Sleep Disturbances in Generalized Anxiety Disorder: The Role of Calcium Homeostasis Imbalance. Other

International journal of … 2023 19 sitasi

Sleep Patterns Modify the Association between Vitamin D Status and Coronary Heart Disease: Results from NHANES 2005-2008. Other

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Integrative Approaches in the Treatment of Patients Affected by Lymphoma. Review

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Complementary and Integrative Approaches to Sleep Disorders in Children. Review

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Vitamin D deficiency promoting non-24 h sleep-wake disorder: a case report. Case Report

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The roles of serum vitamin D and tobacco smoke exposure in insomnia: a cross-sectional study of adults in the United … Other

Frontiers in nutrition 2023 3 sitasi

Early risk assessment and prediction model for osteoporosis based on traditional Chinese medicine syndromes. Other

Heliyon 2023 3 sitasi

The Prevalence of Restless Legs Syndrome Among Pregnant Women in Saudi Arabia. Other

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Assessing the interaction effects of brain structure longitudinal changes and life environmental factors on depression and anxiety. Other

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Digital Addiction and Sleep. Review

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The Role of Vitamin D in Sleep Disorders of Children and Adolescents: A Systematic Review. Systematic Review

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Observational and Genetic Associations of Modifiable Risk Factors with Aortic Valve Stenosis: A Prospective Cohort Study of 0.5 Million Participants. Observational

Nutrients 2022 14 sitasi

Sleep status in multiple sclerosis: Role of vitamin D and body mass index. Other

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Tantali fibromyalgic supplicium: Is there any relief with the antidepressant employment? A systematic review. Systematic Review

Pharmacological research 2022 9 sitasi

Behavioral sleep medicine-The need for harmonization of clinical best practice outcome measures in children and adolescents with intellectual or developmental … Review

Frontiers in psychiatry 2022 8 sitasi

Sleep patterns modify the association of 25(OH)D with poor cardiovascular health in pregnant women. Other

Frontiers in nutrition 2022 4 sitasi

The use of dietary supplements for mental health among the Saudi population: A cross-sectional survey. Other

Saudi pharmaceutical journal … 2022 4 sitasi

Vitamin D levels in primary care patients: correlations with clinical, seasonal, and quality-of-life parameters. Other

Family practice 2022 2 sitasi

Associations of serum 25-hydroxyvitamin D and subjective sleep measures in an arctic population: Insights from the population-based Tromsø Study. Other

Sleep medicine: X 2022 2 sitasi

Dietary Intake and Mental Health among Saudi Adults during COVID-19 Lockdown. Other

International journal of … 2021 25 sitasi

Excessive Daytime Sleepiness is Associated With Malnutrition, Dysphagia, and Vitamin D Deficiency in Older Adults. Other

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Nutraceuticals for Sleep Disorders. Review

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No improvement of sleep from vitamin D supplementation: insights from a randomized controlled trial. Other

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High-dose Vitamin D Supplementation and Improvement in Cognitive Abilities, Insomnia, and Daytime Sleepiness in Adolescent Girls. Other

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Sleep and pain: recent insights, mechanisms, and future directions in the investigation of this relationship. Review

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Baseline Vitamin D Status, Sleep Patterns, and the Risk of Incident Type 2 Diabetes in Data From the UK Biobank … Other

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Quality of life of patients more than 1 year after surgery for thyroid cancer. Other

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Efficacy of low-fat milk and yogurt fortified with encapsulated vitamin D3 on improvement in symptoms of insomnia and quality of … Other

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The relationship between neuropsychological function and responsiveness to vitamin D supplementation using artificial neural networks. Other

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Relationship Between Nutritional Status and Insomnia Severity in Older Adults. Other

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Pharmacotherapeutic management of sleep disorders in children with neurodevelopmental disorders. Review

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Relationship between 25-Hydroxyvitamin D, bone density, and Parkinson's disease symptoms. Other

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Association between Vitamin D Status and Premenstrual Symptoms. Other

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Sleep and biological parameters in professional burnout: A psychophysiological characterization. Other

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Complement systems C4, C3 and CH50 not subject to a circadian rhythm. Other

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Low serum 25-hydroxyvitamin D concentrations in chronic insomnia patients and the association with poor treatment outcome at 2months. Other

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Vitamin D deficiency changes the intestinal microbiome reducing B vitamin production in the gut. The resulting lack of pantothenic acid … Other

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Iron Deficiency, Zinc, Magnesium, Vitamin Deficiencies in Crohn's Disease: Substitute or Not? Review

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Association between Sleep Duration, Insomnia Symptoms and Bone Mineral Density in Older Boston Puerto Rican Adults. Other

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Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

general:: 600-800 IU/day
deficiency:: 1,000-5,000 IU/day

Batas atas: 4,000 IU/day

Dosis yang Diteliti dalam Penelitian

Dosis	Durasi	Efek	N
None	--	Positive	--
None	--	Mixed	--
None	--	Mixed	--
None	--	Mixed	--
tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral	--	Positive	--
None	--	Mixed	--
None	--	Positive	--
None	--	Positive	--

Waktu terbaik diminum: Morning with a meal containing fat; avoid evening dosing

Safety & Side Effects

Efek Samping yang Dilaporkan

⚠ Hypercalcemia at high doses
⚠ Nausea
⚠ Constipation
⚠ Kidney stones (rare, with excessive intake)

Interaksi yang Diketahui

● Corticosteroids — reduce calcium absorption, affecting vitamin D metabolism
● Weight-loss drugs (orlistat) — may reduce vitamin D absorption
● Statins — vitamin D may affect statin metabolism

Asupan atas yang dapat ditoleransi: 4,000 IU/day

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Vitamin D help with Insomnia?

Based on 56 studies with 685,966 participants, there is strong evidence from multiple clinical trials that Vitamin D may support Insomnia management. Our evidence grade is A (Strong Evidence).

How much Vitamin D should I take for Insomnia?

Studies have used various dosages. A commonly studied range is 600-800 IU/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Vitamin D?

Reported side effects may include Hypercalcemia at high doses, Nausea, Constipation, Kidney stones (rare, with excessive intake). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Vitamin D and Insomnia?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 56 peer-reviewed studies with 685,966 total participants. The overall direction of effect is mixed.

Related Evidence

Bahan lain untuk Insomnia

Melatonin A Akar Valerian A CBD A Asam Lemak Omega-3 A Tryptophan A Lavender A

Vitamin D untuk kondisi lain

Insomnia Pemeliharaan Tidur D

Kesimpulan Singkat

Berdasarkan 53 studi (3 meta-analyses, 1 RCT) dengan 685,942 peserta secara total. Hasil bervariasi di antara studi-studi tersebut.

Evidence Strength92%

High confidence

Rincian Studi

RCT (5)Meta (1)Other (50)

Bandingkan Alternatif

Lihat bagaimana bahan lain dibandingkan untuk kondisi ini.

Lihat semua bahan untuk Insomnia

Pelajari Lebih Lanjut

Penafian FDA: Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.