Vitamin D für Insomnie
A Evidenz Mehrere große klinische Studien zeigen übereinstimmend signifikante Vorteile.Basierend auf 53 Studien (3 meta-analyses, 1 RCT) mit 685,942 Teilnehmern insgesamt. Die Ergebnisse sind uneinheitlich zwischen den Studien.
Fazit
The evidence on vitamin D for insomnia is mixed — low vitamin D levels are associated with poor sleep, but taking vitamin D supplements does not consistently improve insomnia symptoms.
- 53 studies with 685,942 participants, though mostly from observational research
- Low vitamin D levels are associated with poor sleep in population studies
- Supplementation results are inconsistent — not a reliable standalone sleep aid
- May be most relevant for people who are vitamin D deficient
Key Study Findings
Key Statistics
56
Studien
685966
Teilnehmer
Mixed
Bewertung
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Übliche Dosierungen
- general:
- 600-800 IU/day
- deficiency:
- 1,000-5,000 IU/day
Obergrenze: 4,000 IU/day
In der Forschung untersuchte Dosierungen
| Dosierung | Dauer | Wirkung | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
Beste Einnahmezeit: Morning with a meal containing fat; avoid evening dosing
Safety & Side Effects
Gemeldete Nebenwirkungen
- ⚠ Hypercalcemia at high doses
- ⚠ Nausea
- ⚠ Constipation
- ⚠ Kidney stones (rare, with excessive intake)
Bekannte Wechselwirkungen
- ● Corticosteroids — reduce calcium absorption, affecting vitamin D metabolism
- ● Weight-loss drugs (orlistat) — may reduce vitamin D absorption
- ● Statins — vitamin D may affect statin metabolism
Tolerierbare Höchstaufnahmemenge: 4,000 IU/day
Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.
Frequently Asked Questions
Does Vitamin D help with Insomnie?
How much Vitamin D should I take for Insomnie?
Are there side effects of Vitamin D?
How strong is the evidence for Vitamin D and Insomnie?
Related Evidence
Andere Inhaltsstoffe für Insomnie
Vitamin D für andere Beschwerden
References
- [1] Noor A Hakim. J Steroid Biochem Mol Biol. 2026. Coffee consumption and its association with vitamin D level, lifestyle factors, and mental health symptoms among adults in Saudi Arabia. doi:10.1016/j.jsbmb.2025.106923 PubMed
- [2] Sadeka Tamanna. Adv Exp Med Biol. 2026. Vitamin D and Sleep Disorders. doi:10.1007/978-3-032-04357-3_7 PubMed
- [3] Jet B Muskens et al.. Child Psychiatry Hum Dev. 2025. Novel Insights into Somatic Comorbidities in Children and Adolescents Across Psychiatric Diagnoses: An Explorative Study. doi:10.1007/s10578-023-01587-w PubMed
- [4] Matthew W Kaufman et al.. Am J Lifestyle Med. 2025. Nutritional Supplements for Healthy Aging: A Critical Analysis Review. doi:10.1177/15598276241244725 PubMed
- [5] Izolde Bouloukaki et al.. Clin Nutr ESPEN. 2025. Vitamin D deficiency and its potential associations on the health status of older patients with chronic obstructive pulmonary disease in … doi:10.1016/j.clnesp.2025.04.013 PubMed
- [6] Nodoka Yamashita et al.. J Physiol Anthropol. 2025. Loneliness, insomnia symptoms, social jetlag, and vitamin D deficiency in relation to mental health problems in Japanese female university students: … doi:10.1186/s40101-025-00403-9 PubMed
- [7] Xinyao Li et al.. Front Neurol. 2025. Causal factors for migraine in Mendelian randomization studies: a systematic review and meta-analysis. doi:10.3389/fneur.2025.1660995 PubMed
- [8] Bo Tang et al.. Front Neurol. 2025. The synergistic interaction of vitamin D deficiency and insomnia on dizziness-related handicap in patients with benign paroxysmal positional vertigo. doi:10.3389/fneur.2025.1656528 PubMed
- [9] Lei Luo et al.. Medicine (Baltimore). 2025. Causal relations of trace elements and nutrients with insomnia: A Mendelian randomization study. doi:10.1097/MD.0000000000046075 PubMed
- [10] Magdalena Żebrowska et al.. Res Sq. 2025. Genome wide association study of a Circadian Imbalance Index in 312,935 European ancestry UK Biobank participants identifies loci related to … doi:10.21203/rs.3.rs-8329341/v1 PubMed
- [11] Sai Zhang et al.. Front Neurol. 2025. A multimodal data-based diagnostic model for predicting vestibular migraine: a retrospective study. doi:10.3389/fneur.2025.1723008 PubMed
- [12] Mohammed J Hayyan et al.. Cureus. 2025. Risperidone-Induced Paradoxical Agitation in a Child With Lamb-Shaffer Syndrome, Autism Spectrum Disorder, and Attention Deficit Hyperactivity Disorder: A Case Report. doi:10.7759/cureus.99097 PubMed
- [13] ZhenZhu Zhang et al.. Medicine (Baltimore). 2025. Genetically predicted modifiable risk factors for Helicobacter pylori infection: A Mendelian randomization study. doi:10.1097/MD.0000000000046696 PubMed
- [14] Isidora Semnic et al.. Front Toxicol. 2025. Mercury exposure leading to functional vitamin B12 deficiency and subacute combined degeneration: a case report and literature review. doi:10.3389/ftox.2025.1580275 PubMed
- [15] Rosa M Ortega et al.. Nutr Hosp. 2025. [Nutrition in improving sleep quality and fighting insomnia]. doi:10.20960/nh.06090 PubMed
- [16] Tianci Gao et al.. Front Nutr. 2025. Corrigendum: The roles of serum vitamin D and tobacco smoke exposure in insomnia: a cross-sectional study of adults in the … doi:10.3389/fnut.2025.1632721 PubMed
- [17] Burcu Çevreli et al.. Psychol Health Med. 2025. Beyond bone health: mental and sleep health consequences of vitamin D deficiency in emerging adulthood-findings from a large-scale university study. doi:10.1080/13548506.2025.2587257 PubMed
- [18] Samantha S Moe et al.. Can Fam Physician. 2025. Top studies of 2024 relevant to primary care: From the PEER team. doi:10.46747/cfp.7105309 PubMed
- [19] Ruijie Zhang et al.. Brain Behav. 2025. Genetically Supported Causality Between Micronutrients and Sleep Behaviors: A Two-Sample Mendelian Randomization Study. doi:10.1002/brb3.70237 PubMed
- [20] Yasser Hegazy et al.. Cureus. 2024. Diffuse Large B-Cell Lymphoma Presenting With Hypercalcemia. doi:10.7759/cureus.73642 PubMed
- [21] Rainer H Straub et al.. Neuroimmunomodulation. 2024. A History of Psycho-Neuro-Endocrine Immune Interactions in Rheumatic Diseases. doi:10.1159/000540959 PubMed
- [22] Hannah Wilcox et al.. J Eat Disord. 2024. Clinical and genetic associations for night eating syndrome in a patient biobank. doi:10.1186/s40337-024-01180-z PubMed
- [23] Zakia Zaman et al.. BMC Neurol. 2024. Highly prevalent geriatric medications and their effect on β-amyloid fibril formation. doi:10.1186/s12883-024-03930-7 PubMed
- [24] Yingying Jiang et al.. Nat Sci Sleep. 2024. Causal Relationship Between Micronutrient and Sleep Disorder: A Mendelian Randomization Study. doi:10.2147/NSS.S475171 PubMed
- [25] Yun-Yang Hu et al.. Zhongguo Dang Dai Er Ke Za Zhi. 2024. [Advances in Mendelian randomization studies on autism spectrum disorder]. doi:10.7499/j.issn.1008-8830.2311030 PubMed
- [26] Xiangming Li et al.. Front Nutr. 2024. Commentary: The roles of serum vitamin D and tobacco smoke exposure in insomnia: a cross-sectional study of adults in the … doi:10.3389/fnut.2024.1500041 PubMed
- [27] Hiroshi Kunugi. Psychiatry Clin Neurosci. 2023. Depression and lifestyle: Focusing on nutrition, exercise, and their possible relevance to molecular mechanisms. doi:10.1111/pcn.13551 PubMed
- [28] Elvira Anna Carbone et al.. Int J Environ Res Public Health. 2023. Sleep Disturbances in Generalized Anxiety Disorder: The Role of Calcium Homeostasis Imbalance. doi:10.3390/ijerph20054431 PubMed
- [29] Zuxiang Wu et al.. J Nutr. 2023. Sleep Patterns Modify the Association between Vitamin D Status and Coronary Heart Disease: Results from NHANES 2005-2008. doi:10.1016/j.tjnut.2022.11.028 PubMed
- [30] Ilana Levy Yurkovski et al.. Curr Oncol Rep. 2023. Integrative Approaches in the Treatment of Patients Affected by Lymphoma. doi:10.1007/s11912-023-01476-4 PubMed
- [31] Swapna N Deshpande et al.. Child Adolesc Psychiatr Clin N Am. 2023. Complementary and Integrative Approaches to Sleep Disorders in Children. doi:10.1016/j.chc.2022.08.008 PubMed
- [32] Richard Friedrich Radlberger et al.. Front Neurol. 2023. Vitamin D deficiency promoting non-24 h sleep-wake disorder: a case report. doi:10.3389/fneur.2023.1141835 PubMed
- [33] Tianci Gao et al.. Front Nutr. 2023. The roles of serum vitamin D and tobacco smoke exposure in insomnia: a cross-sectional study of adults in the United … doi:10.3389/fnut.2023.1285494 PubMed
- [34] Dan Liu et al.. Heliyon. 2023. Early risk assessment and prediction model for osteoporosis based on traditional Chinese medicine syndromes. doi:10.1016/j.heliyon.2023.e21501 PubMed
- [35] Saud Alnaaim et al.. Cureus. 2023. The Prevalence of Restless Legs Syndrome Among Pregnant Women in Saudi Arabia. doi:10.7759/cureus.42883 PubMed
- [36] Roland Grad et al.. Am Fam Physician. 2023. Top 20 Research Studies of 2022 for Primary Care Physicians. PubMed
- [37] Xuena Yang et al.. Hum Brain Mapp. 2023. Assessing the interaction effects of brain structure longitudinal changes and life environmental factors on depression and anxiety. doi:10.1002/hbm.26153 PubMed
- [38] Birgitta Dresp-Langley et al.. Int J Environ Res Public Health. 2022. Digital Addiction and Sleep. doi:10.3390/ijerph19116910 PubMed
- [39] Federica Prono et al.. Int J Mol Sci. 2022. The Role of Vitamin D in Sleep Disorders of Children and Adolescents: A Systematic Review. doi:10.3390/ijms23031430 PubMed
- [40] Ninghao Huang et al.. Nutrients. 2022. Observational and Genetic Associations of Modifiable Risk Factors with Aortic Valve Stenosis: A Prospective Cohort Study of 0.5 Million Participants. doi:10.3390/nu14112273 PubMed
- [41] Mohammad Yazdchi et al.. Curr J Neurol. 2022. Sleep status in multiple sclerosis: Role of vitamin D and body mass index. doi:10.18502/cjn.v21i2.10489 PubMed
- [42] Sara Ilari et al.. Pharmacol Res. 2022. Tantali fibromyalgic supplicium: Is there any relief with the antidepressant employment? A systematic review. doi:10.1016/j.phrs.2022.106547 PubMed
- [43] Rosalia Silvestri et al.. Front Psychiatry. 2022. Behavioral sleep medicine-The need for harmonization of clinical best practice outcome measures in children and adolescents with intellectual or developmental … doi:10.3389/fpsyt.2022.1003019 PubMed
- [44] Wan-Jun Yin et al.. Front Nutr. 2022. Sleep patterns modify the association of 25(OH)D with poor cardiovascular health in pregnant women. doi:10.3389/fnut.2022.1013960 PubMed
- [45] Deemah Alateeq et al.. Saudi Pharm J. 2022. The use of dietary supplements for mental health among the Saudi population: A cross-sectional survey. doi:10.1016/j.jsps.2022.03.017 PubMed
- [46] Izolde Bouloukaki et al.. Fam Pract. 2022. Vitamin D levels in primary care patients: correlations with clinical, seasonal, and quality-of-life parameters. doi:10.1093/fampra/cmac012 PubMed
- [47] A U Larsen et al.. Sleep Med X. 2022. Associations of serum 25-hydroxyvitamin D and subjective sleep measures in an arctic population: Insights from the population-based Tromsø Study. doi:10.1016/j.sleepx.2022.100056 PubMed
- [48] Hanan Alfawaz et al.. Int J Environ Res Public Health. 2021. Dietary Intake and Mental Health among Saudi Adults during COVID-19 Lockdown. doi:10.3390/ijerph18041653 PubMed
- [49] Saadet Koc Okudur et al.. J Am Med Dir Assoc. 2021. Excessive Daytime Sleepiness is Associated With Malnutrition, Dysphagia, and Vitamin D Deficiency in Older Adults. doi:10.1016/j.jamda.2021.05.035 PubMed
- [50] Ruhi Ali et al.. Comb Chem High Throughput Screen. 2021. Nutraceuticals for Sleep Disorders. doi:10.2174/1386207324666210121111446 PubMed
- [51] A U Larsen et al.. Sleep Med X. 2021. No improvement of sleep from vitamin D supplementation: insights from a randomized controlled trial. doi:10.1016/j.sleepx.2021.100040 PubMed
- [52] Afsane Bahrami et al.. Basic Clin Neurosci. 2021. High-dose Vitamin D Supplementation and Improvement in Cognitive Abilities, Insomnia, and Daytime Sleepiness in Adolescent Girls. doi:10.32598/bcn.2021.1910.1 PubMed
- [53] Alberto Herrero Babiloni et al.. J Neural Transm (Vienna). 2020. Sleep and pain: recent insights, mechanisms, and future directions in the investigation of this relationship. doi:10.1007/s00702-019-02067-z PubMed
- [54] Mengying Wang et al.. Diabetes Care. 2020. Baseline Vitamin D Status, Sleep Patterns, and the Risk of Incident Type 2 Diabetes in Data From the UK Biobank … doi:10.2337/dc20-1109 PubMed
- [55] Matthias Büttner et al.. Hormones (Athens). 2020. Quality of life of patients more than 1 year after surgery for thyroid cancer. doi:10.1007/s42000-020-00186-x PubMed
- [56] Payam Sharifan et al.. Food Sci Nutr. 2020. Efficacy of low-fat milk and yogurt fortified with encapsulated vitamin D3 on improvement in symptoms of insomnia and quality of … doi:10.1002/fsn3.1750 PubMed
- [57] Elahe Allahyari et al.. Nutr Health. 2020. The relationship between neuropsychological function and responsiveness to vitamin D supplementation using artificial neural networks. doi:10.1177/0260106020937190 PubMed
- [58] Pinar Soysal et al.. J Am Med Dir Assoc. 2019. Relationship Between Nutritional Status and Insomnia Severity in Older Adults. doi:10.1016/j.jamda.2019.03.030 PubMed
- [59] Oliviero Bruni et al.. Expert Opin Pharmacother. 2019. Pharmacotherapeutic management of sleep disorders in children with neurodevelopmental disorders. doi:10.1080/14656566.2019.1674283 PubMed
- [60] Hui-Jun Zhang et al.. Acta Neurol Scand. 2019. Relationship between 25-Hydroxyvitamin D, bone density, and Parkinson's disease symptoms. doi:10.1111/ane.13141 PubMed
- [61] Alicia C Jarosz et al.. J Acad Nutr Diet. 2019. Association between Vitamin D Status and Premenstrual Symptoms. doi:10.1016/j.jand.2018.06.014 PubMed
- [62] Arnaud Metlaine et al.. PLoS One. 2018. Sleep and biological parameters in professional burnout: A psychophysiological characterization. doi:10.1371/journal.pone.0190607 PubMed
- [63] Thomas Lung et al.. Diagnosis (Berl). 2018. Complement systems C4, C3 and CH50 not subject to a circadian rhythm. doi:10.1515/dx-2018-0003 PubMed
- [64] Kai Zhao et al.. Clin Chim Acta. 2017. Low serum 25-hydroxyvitamin D concentrations in chronic insomnia patients and the association with poor treatment outcome at 2months. doi:10.1016/j.cca.2017.10.024 PubMed
- [65] S C Gominak. Med Hypotheses. 2016. Vitamin D deficiency changes the intestinal microbiome reducing B vitamin production in the gut. The resulting lack of pantothenic acid … doi:10.1016/j.mehy.2016.07.007 PubMed
- [66] Wolfgang Kruis et al.. Dig Dis. 2016. Iron Deficiency, Zinc, Magnesium, Vitamin Deficiencies in Crohn's Disease: Substitute or Not? doi:10.1159/000443012 PubMed
- [67] Jinya Niu et al.. PLoS One. 2015. Association between Sleep Duration, Insomnia Symptoms and Bone Mineral Density in Older Boston Puerto Rican Adults. doi:10.1371/journal.pone.0132342 PubMed
- [68] Tomasella Quattrocchi et al.. J Obstet Gynaecol Res. 2015. Effects of a phyto complex on well-being of climacteric women. doi:10.1111/jog.12659 PubMed
- [69] Richard Glickman-Simon et al.. Explore (NY). 2015. Viscum album (mistletoe) for pancreatic cancer, electromagnetic field therapy for osteoarthritis, homeopathy for multidrug-resistant tuberculosis, vitamin D for depression, acupuncture … doi:10.1016/j.explore.2015.02.013 PubMed
- [70] Joshua Bauml et al.. Breast Cancer Res. 2015. Arthralgia among women taking aromatase inhibitors: is there a shared inflammatory mechanism with co-morbid fatigue and insomnia? doi:10.1186/s13058-015-0599-7 PubMed
- [71] Michael A Grandner et al.. J Sleep Res. 2014. Sleep symptoms associated with intake of specific dietary nutrients. doi:10.1111/jsr.12084 PubMed
- [72] May A Beydoun et al.. PLoS One. 2014. Serum nutritional biomarkers and their associations with sleep among US adults in recent national surveys. doi:10.1371/journal.pone.0103490 PubMed
- [73] Sandy Slow et al.. BMJ. 2014. Effect of monthly vitamin D3 supplementation in healthy adults on adverse effects of earthquakes: randomised controlled trial. doi:10.1136/bmj.g7260 PubMed
- [74] S El Hechmi et al.. Encephale. 2014. [Psychotic disorder induced by Fahr's syndrome: a case report]. doi:10.1016/j.encep.2013.04.012 PubMed
- [75] Elisabeth A Frazier et al.. J Child Adolesc Psychopharmacol. 2013. Nutritional and safety outcomes from an open-label micronutrient intervention for pediatric bipolar spectrum disorders. doi:10.1089/cap.2012.0098 PubMed
- [76] Amanda M Huskey et al.. Ann Pharmacother. 2013. Occurrence of milnacipran-associated morbilliform rash and serotonin toxicity. doi:10.1345/aph.1R474 PubMed
- [77] Robert Ryan et al.. Curr HIV Res. 2013. Outcomes in older versus younger patients over 96 weeks in HIV-1- infected patients treated with rilpivirine or efavirenz in ECHO … doi:10.2174/1570162x12666140128121900 PubMed
- [78] C Agosta et al.. Minerva Ginecol. 2011. Randomized controlled study on clinical efficacy of isoflavones plus Lactobacillus sporogenes, associated or not with a natural anxiolytic agent in … PubMed
- [79] Barbara J Messinger-Rapport et al.. J Am Med Dir Assoc. 2007. Intensive session: New approaches to medical issues in long-term care. doi:10.1016/j.jamda.2007.07.002 PubMed
- [80] Achille Norsa et al.. Cancer Biother Radiopharm. 2006. Somatostatin, retinoids, melatonin, vitamin D, bromocriptine, and cyclophosphamide in advanced non-small-cell lung cancer patients with low performance status. doi:10.1089/cbr.2006.21.68 PubMed
- [81] M Mucci et al.. Minerva Ginecol. 2006. Soy isoflavones, lactobacilli, Magnolia bark extract, vitamin D3 and calcium. Controlled clinical study in menopause. PubMed
- [82] Wen-Ching Chen et al.. Am J Kidney Dis. 2006. Sleep behavior disorders in a large cohort of chinese (Taiwanese) patients maintained by long-term hemodialysis. doi:10.1053/j.ajkd.2006.04.079 PubMed
- [83] H Hassikou et al.. Ann Endocrinol (Paris). 2006. [Hypoparathyroidism associated with systemic lupus erythematosus: a case]. doi:10.1016/s0003-4266(06)73016-5 PubMed
- [84] Wolfgang Kemmler et al.. Med Sci Sports Exerc. 2005. Exercise effects on menopausal risk factors of early postmenopausal women: 3-yr Erlangen fitness osteoporosis prevention study results. doi:10.1249/01.mss.0000152678.20239.76 PubMed
- [85] P R Koninckx et al.. Maturitas. 1993. Endometrial effects during hormone replacement therapy with a sequential oestradiol valerate/cyproterone acetate preparation. doi:10.1016/0378-5122(93)90054-l PubMed
- [86] P Bech et al.. Acta Psychiatr Scand. 1979. Depression or asthenia related to metabolic disturbances in obese patients after intestinal bypass surgery. doi:10.1111/j.1600-0447.1979.tb00245.x PubMed
FDA-Haftungsausschluss: Diese Aussagen wurden nicht von der Food and Drug Administration bewertet. Die Produkte und Informationen auf dieser Website sind nicht dazu bestimmt, Krankheiten zu diagnostizieren, zu behandeln, zu heilen oder zu verhindern. Die dargestellten Evidenzbewertungen basieren auf unserer Analyse veröffentlichter begutachteter Forschung und stellen keine medizinische Beratung dar. Konsultieren Sie immer Ihren Arzt, bevor Sie mit der Einnahme von Nahrungsergänzungsmitteln beginnen.