Vitamin D für Insomnie

Basierend auf 53 Studien (3 meta-analyses, 1 RCT) mit 685,942 Teilnehmern insgesamt. Die Ergebnisse sind uneinheitlich zwischen den Studien.

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Fazit

The evidence on vitamin D for insomnia is mixed — low vitamin D levels are associated with poor sleep, but taking vitamin D supplements does not consistently improve insomnia symptoms.

53 studies with 685,942 participants, though mostly from observational research
Low vitamin D levels are associated with poor sleep in population studies
Supplementation results are inconsistent — not a reliable standalone sleep aid
May be most relevant for people who are vitamin D deficient

Key Study Findings

review

Vitamin D and Sleep Disorders.

Dose: None vs.: Placebo Wirkung: None None

review

Top studies of 2024 relevant to primary care: From the PEER team.

Dose: None vs.: Placebo Wirkung: None None

review

Nutritional Supplements for Healthy Aging: A Critical Analysis Review.

Dose: None vs.: Placebo Wirkung: None None

Mendelian randomization

Genetically Supported Causality Between Micronutrients and Sleep Behaviors: A Two-Sample Mendelian Randomization Study.

Dose: None vs.: Placebo Wirkung: Folate vs chronotype OR 1.09 (95% CI 1.01-1.17); Vitamin B6 vs chronotype OR 0.91 (95% CI 0.86-0.96) Folate p=0.02; Vitamin B6 p=1.

review

[Nutrition in improving sleep quality and fighting insomnia].

Dose: tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral vs.: Placebo Wirkung: None None

systematic review and meta-analysis

Causal factors for migraine in Mendelian randomization studies: a systematic review and meta-analysis.

Dose: None vs.: Placebo Wirkung: None None

Key Statistics

Studien

685966

Teilnehmer

↔

Mixed

Bewertung

Referenced Papers

Coffee consumption and its association with vitamin D level, lifestyle factors, and mental health symptoms among adults in Saudi Arabia. Other

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Vitamin D and Sleep Disorders. Review

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Novel Insights into Somatic Comorbidities in Children and Adolescents Across Psychiatric Diagnoses: An Explorative Study. Other

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Nutritional Supplements for Healthy Aging: A Critical Analysis Review. Review

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Vitamin D deficiency and its potential associations on the health status of older patients with chronic obstructive pulmonary disease in … Other

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Loneliness, insomnia symptoms, social jetlag, and vitamin D deficiency in relation to mental health problems in Japanese female university students: … Other

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Causal factors for migraine in Mendelian randomization studies: a systematic review and meta-analysis. Systematic Review

Frontiers in neurology 2025 1 Zitierungen

The synergistic interaction of vitamin D deficiency and insomnia on dizziness-related handicap in patients with benign paroxysmal positional vertigo. Other

Frontiers in neurology 2025 1 Zitierungen

Causal relations of trace elements and nutrients with insomnia: A Mendelian randomization study. Other

Medicine 2025

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Corrigendum: The roles of serum vitamin D and tobacco smoke exposure in insomnia: a cross-sectional study of adults in the … Other

Frontiers in nutrition 2025

Beyond bone health: mental and sleep health consequences of vitamin D deficiency in emerging adulthood-findings from a large-scale university study. Other

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Genetically Supported Causality Between Micronutrients and Sleep Behaviors: A Two-Sample Mendelian Randomization Study. Other

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Diffuse Large B-Cell Lymphoma Presenting With Hypercalcemia. Case Report

Cureus 2024 2 Zitierungen

A History of Psycho-Neuro-Endocrine Immune Interactions in Rheumatic Diseases. Review

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Clinical and genetic associations for night eating syndrome in a patient biobank. Other

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Highly prevalent geriatric medications and their effect on β-amyloid fibril formation. Other

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Causal Relationship Between Micronutrient and Sleep Disorder: A Mendelian Randomization Study. Other

Nature and science … 2024 1 Zitierungen

[Advances in Mendelian randomization studies on autism spectrum disorder]. Review

Zhongguo dang dai … 2024

Commentary: The roles of serum vitamin D and tobacco smoke exposure in insomnia: a cross-sectional study of adults in the … Other

Frontiers in nutrition 2024

Depression and lifestyle: Focusing on nutrition, exercise, and their possible relevance to molecular mechanisms. Meta-Analysis

Psychiatry and clinical … 2023 67 Zitierungen

Sleep Disturbances in Generalized Anxiety Disorder: The Role of Calcium Homeostasis Imbalance. Other

International journal of … 2023 19 Zitierungen

Sleep Patterns Modify the Association between Vitamin D Status and Coronary Heart Disease: Results from NHANES 2005-2008. Other

The Journal of … 2023 9 Zitierungen

Integrative Approaches in the Treatment of Patients Affected by Lymphoma. Review

Current oncology reports 2023 5 Zitierungen

Complementary and Integrative Approaches to Sleep Disorders in Children. Review

Child and adolescent … 2023 5 Zitierungen

Vitamin D deficiency promoting non-24 h sleep-wake disorder: a case report. Case Report

Frontiers in neurology 2023 3 Zitierungen

The roles of serum vitamin D and tobacco smoke exposure in insomnia: a cross-sectional study of adults in the United … Other

Frontiers in nutrition 2023 3 Zitierungen

Early risk assessment and prediction model for osteoporosis based on traditional Chinese medicine syndromes. Other

Heliyon 2023 3 Zitierungen

The Prevalence of Restless Legs Syndrome Among Pregnant Women in Saudi Arabia. Other

Cureus 2023 3 Zitierungen

Top 20 Research Studies of 2022 for Primary Care Physicians. Other

American family physician 2023

Assessing the interaction effects of brain structure longitudinal changes and life environmental factors on depression and anxiety. Other

Human brain mapping 2023

Digital Addiction and Sleep. Review

International journal of … 2022 107 Zitierungen

The Role of Vitamin D in Sleep Disorders of Children and Adolescents: A Systematic Review. Systematic Review

International journal of … 2022 36 Zitierungen

Observational and Genetic Associations of Modifiable Risk Factors with Aortic Valve Stenosis: A Prospective Cohort Study of 0.5 Million Participants. Observational

Nutrients 2022 14 Zitierungen

Sleep status in multiple sclerosis: Role of vitamin D and body mass index. Other

Current journal of … 2022 11 Zitierungen

Tantali fibromyalgic supplicium: Is there any relief with the antidepressant employment? A systematic review. Systematic Review

Pharmacological research 2022 9 Zitierungen

Behavioral sleep medicine-The need for harmonization of clinical best practice outcome measures in children and adolescents with intellectual or developmental … Review

Frontiers in psychiatry 2022 8 Zitierungen

Sleep patterns modify the association of 25(OH)D with poor cardiovascular health in pregnant women. Other

Frontiers in nutrition 2022 4 Zitierungen

The use of dietary supplements for mental health among the Saudi population: A cross-sectional survey. Other

Saudi pharmaceutical journal … 2022 4 Zitierungen

Vitamin D levels in primary care patients: correlations with clinical, seasonal, and quality-of-life parameters. Other

Family practice 2022 2 Zitierungen

Associations of serum 25-hydroxyvitamin D and subjective sleep measures in an arctic population: Insights from the population-based Tromsø Study. Other

Sleep medicine: X 2022 2 Zitierungen

Dietary Intake and Mental Health among Saudi Adults during COVID-19 Lockdown. Other

International journal of … 2021 25 Zitierungen

Excessive Daytime Sleepiness is Associated With Malnutrition, Dysphagia, and Vitamin D Deficiency in Older Adults. Other

Journal of the … 2021 22 Zitierungen

Nutraceuticals for Sleep Disorders. Review

Combinatorial chemistry & … 2021 16 Zitierungen

No improvement of sleep from vitamin D supplementation: insights from a randomized controlled trial. Other

Sleep medicine: X 2021 9 Zitierungen

High-dose Vitamin D Supplementation and Improvement in Cognitive Abilities, Insomnia, and Daytime Sleepiness in Adolescent Girls. Other

Basic and clinical … 2021 2 Zitierungen

Sleep and pain: recent insights, mechanisms, and future directions in the investigation of this relationship. Review

Journal of neural … 2020 194 Zitierungen

Baseline Vitamin D Status, Sleep Patterns, and the Risk of Incident Type 2 Diabetes in Data From the UK Biobank … Other

Diabetes care 2020 110 Zitierungen

Quality of life of patients more than 1 year after surgery for thyroid cancer. Other

Hormones (Athens, Greece) 2020 20 Zitierungen

Efficacy of low-fat milk and yogurt fortified with encapsulated vitamin D3 on improvement in symptoms of insomnia and quality of … Other

Food science & … 2020 17 Zitierungen

The relationship between neuropsychological function and responsiveness to vitamin D supplementation using artificial neural networks. Other

Nutrition and health 2020 4 Zitierungen

Relationship Between Nutritional Status and Insomnia Severity in Older Adults. Other

Journal of the … 2019 58 Zitierungen

Pharmacotherapeutic management of sleep disorders in children with neurodevelopmental disorders. Review

Expert opinion on … 2019 49 Zitierungen

Relationship between 25-Hydroxyvitamin D, bone density, and Parkinson's disease symptoms. Other

Acta neurologica Scandinavica 2019 36 Zitierungen

Association between Vitamin D Status and Premenstrual Symptoms. Other

Journal of the … 2019 16 Zitierungen

Sleep and biological parameters in professional burnout: A psychophysiological characterization. Other

PloS one 2018 69 Zitierungen

Complement systems C4, C3 and CH50 not subject to a circadian rhythm. Other

Diagnosis (Berlin, Germany) 2018 4 Zitierungen

Low serum 25-hydroxyvitamin D concentrations in chronic insomnia patients and the association with poor treatment outcome at 2months. Other

Clinica chimica acta; … 2017 14 Zitierungen

Vitamin D deficiency changes the intestinal microbiome reducing B vitamin production in the gut. The resulting lack of pantothenic acid … Other

Medical hypotheses 2016 105 Zitierungen

Iron Deficiency, Zinc, Magnesium, Vitamin Deficiencies in Crohn's Disease: Substitute or Not? Review

Digestive diseases (Basel, … 2016 41 Zitierungen

Association between Sleep Duration, Insomnia Symptoms and Bone Mineral Density in Older Boston Puerto Rican Adults. Other

PloS one 2015 35 Zitierungen

Effects of a phyto complex on well-being of climacteric women. Observational

The journal of … 2015 13 Zitierungen

Viscum album (mistletoe) for pancreatic cancer, electromagnetic field therapy for osteoarthritis, homeopathy for multidrug-resistant tuberculosis, vitamin D for depression, acupuncture … Other

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Arthralgia among women taking aromatase inhibitors: is there a shared inflammatory mechanism with co-morbid fatigue and insomnia? Other

Breast cancer research … 2015

Sleep symptoms associated with intake of specific dietary nutrients. Other

Journal of sleep … 2014 236 Zitierungen

Serum nutritional biomarkers and their associations with sleep among US adults in recent national surveys. Other

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Effect of monthly vitamin D3 supplementation in healthy adults on adverse effects of earthquakes: randomised controlled trial. RCT

BMJ (Clinical research … 2014 8 Zitierungen

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Somatostatin, retinoids, melatonin, vitamin D, bromocriptine, and cyclophosphamide in advanced non-small-cell lung cancer patients with low performance status. Other

Cancer biotherapy & … 2006 29 Zitierungen

Soy isoflavones, lactobacilli, Magnolia bark extract, vitamin D3 and calcium. Controlled clinical study in menopause. RCT

Minerva ginecologica 2006

Sleep behavior disorders in a large cohort of chinese (Taiwanese) patients maintained by long-term hemodialysis. Other

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Exercise effects on menopausal risk factors of early postmenopausal women: 3-yr Erlangen fitness osteoporosis prevention study results. Other

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Endometrial effects during hormone replacement therapy with a sequential oestradiol valerate/cyproterone acetate preparation. RCT

Maturitas 1993

Depression or asthenia related to metabolic disturbances in obese patients after intestinal bypass surgery. Other

Acta psychiatrica Scandinavica 1979 22 Zitierungen

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Übliche Dosierungen

general:: 600-800 IU/day
deficiency:: 1,000-5,000 IU/day

Obergrenze: 4,000 IU/day

In der Forschung untersuchte Dosierungen

Dosierung	Dauer	Wirkung	N
None	--	Positive	--
None	--	Mixed	--
None	--	Mixed	--
None	--	Mixed	--
tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral	--	Positive	--
None	--	Mixed	--
None	--	Positive	--
None	--	Positive	--

Beste Einnahmezeit: Morning with a meal containing fat; avoid evening dosing

Safety & Side Effects

Gemeldete Nebenwirkungen

⚠ Hypercalcemia at high doses
⚠ Nausea
⚠ Constipation
⚠ Kidney stones (rare, with excessive intake)

Bekannte Wechselwirkungen

● Corticosteroids — reduce calcium absorption, affecting vitamin D metabolism
● Weight-loss drugs (orlistat) — may reduce vitamin D absorption
● Statins — vitamin D may affect statin metabolism

Tolerierbare Höchstaufnahmemenge: 4,000 IU/day

Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.

Frequently Asked Questions

Does Vitamin D help with Insomnie?

Based on 56 studies with 685,966 participants, there is strong evidence from multiple clinical trials that Vitamin D may support Insomnie management. Our evidence grade is A (Strong Evidence).

How much Vitamin D should I take for Insomnie?

Studies have used various dosages. A commonly studied range is 600-800 IU/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Vitamin D?

Reported side effects may include Hypercalcemia at high doses, Nausea, Constipation, Kidney stones (rare, with excessive intake). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Vitamin D and Insomnie?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 56 peer-reviewed studies with 685,966 total participants. The overall direction of effect is mixed.

Related Evidence

Andere Inhaltsstoffe für Insomnie

Melatonin A Baldrianwurzel A CBD A Omega-3-Fettsäuren A Tryptophan A Lavendel A

Vitamin D für andere Beschwerden

Durchschlafstörung D

Kurzfazit

Basierend auf 53 Studien (3 meta-analyses, 1 RCT) mit 685,942 Teilnehmern insgesamt. Die Ergebnisse sind uneinheitlich zwischen den Studien.

Evidence Strength92%

High confidence

Studienübersicht

RCT (5)Meta (1)Other (50)

Alternativen vergleichen

Sehen Sie, wie andere Inhaltsstoffe bei dieser Beschwerde abschneiden.

Alle Inhaltsstoffe ansehen für Insomnie

Mehr erfahren

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