Vitamina D para Insônia

Baseado em 53 estudos (3 meta-analyses, 1 RCT) com 685,942 participantes no total. Os resultados são variados entre os estudos.

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Conclusão

The evidence on vitamin D for insomnia is mixed — low vitamin D levels are associated with poor sleep, but taking vitamin D supplements does not consistently improve insomnia symptoms.

53 studies with 685,942 participants, though mostly from observational research
Low vitamin D levels are associated with poor sleep in population studies
Supplementation results are inconsistent — not a reliable standalone sleep aid
May be most relevant for people who are vitamin D deficient

Key Study Findings

review

Vitamin D and Sleep Disorders.

Dose: None vs: Placebo Efeito: None None

review

Top studies of 2024 relevant to primary care: From the PEER team.

Dose: None vs: Placebo Efeito: None None

review

Nutritional Supplements for Healthy Aging: A Critical Analysis Review.

Dose: None vs: Placebo Efeito: None None

Mendelian randomization

Genetically Supported Causality Between Micronutrients and Sleep Behaviors: A Two-Sample Mendelian Randomization Study.

Dose: None vs: Placebo Efeito: Folate vs chronotype OR 1.09 (95% CI 1.01-1.17); Vitamin B6 vs chronotype OR 0.91 (95% CI 0.86-0.96) Folate p=0.02; Vitamin B6 p=1.

review

[Nutrition in improving sleep quality and fighting insomnia].

Dose: tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral vs: Placebo Efeito: None None

systematic review and meta-analysis

Causal factors for migraine in Mendelian randomization studies: a systematic review and meta-analysis.

Dose: None vs: Placebo Efeito: None None

Key Statistics

Estudos

685966

Participantes

↔

Mixed

Nota

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Depression and lifestyle: Focusing on nutrition, exercise, and their possible relevance to molecular mechanisms. Meta-Analysis

Psychiatry and clinical … 2023 67 citações

Sleep Disturbances in Generalized Anxiety Disorder: The Role of Calcium Homeostasis Imbalance. Other

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Sleep Patterns Modify the Association between Vitamin D Status and Coronary Heart Disease: Results from NHANES 2005-2008. Other

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Integrative Approaches in the Treatment of Patients Affected by Lymphoma. Review

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Complementary and Integrative Approaches to Sleep Disorders in Children. Review

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Vitamin D deficiency promoting non-24 h sleep-wake disorder: a case report. Case Report

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The roles of serum vitamin D and tobacco smoke exposure in insomnia: a cross-sectional study of adults in the United … Other

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Early risk assessment and prediction model for osteoporosis based on traditional Chinese medicine syndromes. Other

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The Prevalence of Restless Legs Syndrome Among Pregnant Women in Saudi Arabia. Other

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Assessing the interaction effects of brain structure longitudinal changes and life environmental factors on depression and anxiety. Other

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The Role of Vitamin D in Sleep Disorders of Children and Adolescents: A Systematic Review. Systematic Review

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Observational and Genetic Associations of Modifiable Risk Factors with Aortic Valve Stenosis: A Prospective Cohort Study of 0.5 Million Participants. Observational

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Behavioral sleep medicine-The need for harmonization of clinical best practice outcome measures in children and adolescents with intellectual or developmental … Review

Frontiers in psychiatry 2022 8 citações

Sleep patterns modify the association of 25(OH)D with poor cardiovascular health in pregnant women. Other

Frontiers in nutrition 2022 4 citações

The use of dietary supplements for mental health among the Saudi population: A cross-sectional survey. Other

Saudi pharmaceutical journal … 2022 4 citações

Vitamin D levels in primary care patients: correlations with clinical, seasonal, and quality-of-life parameters. Other

Family practice 2022 2 citações

Associations of serum 25-hydroxyvitamin D and subjective sleep measures in an arctic population: Insights from the population-based Tromsø Study. Other

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Dietary Intake and Mental Health among Saudi Adults during COVID-19 Lockdown. Other

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Excessive Daytime Sleepiness is Associated With Malnutrition, Dysphagia, and Vitamin D Deficiency in Older Adults. Other

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High-dose Vitamin D Supplementation and Improvement in Cognitive Abilities, Insomnia, and Daytime Sleepiness in Adolescent Girls. Other

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Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosagens Comumente Utilizadas

general:: 600-800 IU/day
deficiency:: 1,000-5,000 IU/day

Limite superior: 4,000 IU/day

Dosagens Estudadas em Pesquisas

Dosagem	Duração	Efeito	N
None	--	Positive	--
None	--	Mixed	--
None	--	Mixed	--
None	--	Mixed	--
tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral	--	Positive	--
None	--	Mixed	--
None	--	Positive	--
None	--	Positive	--

Melhor horário: Morning with a meal containing fat; avoid evening dosing

Safety & Side Effects

Efeitos Colaterais Relatados

⚠ Hypercalcemia at high doses
⚠ Nausea
⚠ Constipation
⚠ Kidney stones (rare, with excessive intake)

Interações Conhecidas

● Corticosteroids — reduce calcium absorption, affecting vitamin D metabolism
● Weight-loss drugs (orlistat) — may reduce vitamin D absorption
● Statins — vitamin D may affect statin metabolism

Ingestão máxima tolerável: 4,000 IU/day

Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.

Frequently Asked Questions

Does Vitamina D help with Insônia?

Based on 56 studies with 685,966 participants, there is strong evidence from multiple clinical trials that Vitamina D may support Insônia management. Our evidence grade is A (Strong Evidence).

How much Vitamina D should I take for Insônia?

Studies have used various dosages. A commonly studied range is 600-800 IU/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Vitamina D?

Reported side effects may include Hypercalcemia at high doses, Nausea, Constipation, Kidney stones (rare, with excessive intake). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Vitamina D and Insônia?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 56 peer-reviewed studies with 685,966 total participants. The overall direction of effect is mixed.

Related Evidence

Outros ingredientes para Insônia

Melatonina A Raiz de valeriana A CBD A Ácidos graxos ômega-3 A Triptófano A Lavanda A

Vitamina D para outras condições

Insônia de Manutenção do Sono D

Veredito Rápido

Baseado em 53 estudos (3 meta-analyses, 1 RCT) com 685,942 participantes no total. Os resultados são variados entre os estudos.

Evidence Strength92%

High confidence

Detalhamento dos Estudos

RCT (5)Meta (1)Other (50)

Comparar Alternativas

Veja como outros ingredientes se comparam para esta condição.

Ver todos os ingredientes para Insônia

Saiba Mais

Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.