Melissenblatt für Insomnie
ABasierend auf 21 Studien (3 meta-analyses, 2 RCTs) mit 933 Teilnehmern insgesamt. 17/21 Studien zeigen positive Effekte.
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A
Fazit
Lemon balm is well-supported by research as a gentle, natural supplement that may help improve sleep quality for people with insomnia.
- 17 out of 21 studies show positive effects, with Grade A evidence rating
- A 2023 double-blind RCT showed improved sleep and emotional well-being in adults
- Works through GABA-modulating properties confirmed in multiple systematic reviews
- Effective both alone and in combination with other herbs like valerian
Key Study Findings
systematic review
n=451
Double-blind
Effectiveness of Homoeopathic Treatments for Sleep Disorders in Children and Adolescents: A Systematic Review According …
Dose: various homoeopathic remedies (complex homoeopathy, Melissa officinalis 12C, individualised homoeopa
vs.: Placebo
Wirkung: bruxism: ΔVAS -2.36 vs -1.72; enuresis: median -2.4 nights/week
0.05 (bruxism); < 0.04 (enures
Review
Integrative sleep management: from molecular pathways to conventional and herbal treatments.
Dose: None
vs.: Placebo
Wirkung: None
None
Review
n=51
Over-the-counter products for insomnia in adults: A scoping review of randomised controlled trials.
Dose: None
vs.: Placebo
Wirkung: 41/51 studies demonstrated positive effects on insomnia symptoms
None
Review
The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, …
Dose: None
vs.: Placebo
Wirkung: None
None
Review
Therapeutic potential of hypnotic herbal medicines: A comprehensive review.
Dose: None
vs.: None
Outcome: Sleep quality
Wirkung: None
None
Population: Insomnia patients
randomized controlled trial
n=100
3 weeks
Double-blind
The possible "calming effect" of subchronic supplementation of a standardised phospholipid carrier-based Melissa officinalis L. …
Dose: 200 mg twice daily (400 mg/day) for 3 weeks
vs.: Placebo
Wirkung: significant improvements in all scores (depression, anxiety, stress, positive/negative affect, menta
<0.001
Key Statistics
22
Studien
933
Teilnehmer
↑
Positive
A
Bewertung
Referenced Papers
Naunyn-Schmiedeberg's archives of …
2025
4 Zitierungen
Over-the-counter products for insomnia in adults: A scoping review of randomised controlled trials.
Review
Sleep medicine
2025
4 Zitierungen
Molecules (Basel, Switzerland)
2025
2 Zitierungen
Children (Basel, Switzerland)
2025
Phytotherapy research : …
2024
14 Zitierungen
Nutrients
2024
6 Zitierungen
Frontiers in pharmacology
2023
11 Zitierungen
A Perspective on Missing Aspects in Ongoing Purification Research towards Melissa officinalis.
Review
Foods (Basel, Switzerland)
2023
7 Zitierungen
Molecules (Basel, Switzerland)
2022
90 Zitierungen
Nutrients
2021
85 Zitierungen
Combinatorial chemistry & …
2021
16 Zitierungen
Advances in experimental …
2021
7 Zitierungen
Journal of ethnopharmacology
2020
19 Zitierungen
Complementary therapies in …
2019
26 Zitierungen
Assessing insomnia management in community pharmacy setting in Jordan: A simulated patient approach.
Other
PloS one
2019
19 Zitierungen
GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence.
Systematic Review
Phytotherapy research : …
2018
95 Zitierungen
Clinical nutrition ESPEN
2018
78 Zitierungen
Integrative medicine research
2018
18 Zitierungen
Journal of alternative …
2018
15 Zitierungen
Journal of evidence-based …
2017
204 Zitierungen
Electronic physician
2017
102 Zitierungen
Saudi pharmaceutical journal …
2017
19 Zitierungen
Journal of ethnopharmacology
2015
68 Zitierungen
Research in pharmaceutical …
2015
14 Zitierungen
Phytomedicine : international …
2014
30 Zitierungen
Mediterranean journal of …
2011
Medical science monitor …
2009
85 Zitierungen
Revista medico-chirurgicala a …
2008
24 Zitierungen
Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence.
Review
Journal of clinical …
2005
Integrative cancer therapies
2004
59 Zitierungen
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Übliche Dosierungen
- sleep:
- 300-600 mg extract, before bed
Obergrenze: Not established
In der Forschung untersuchte Dosierungen
| Dosierung | Dauer | Wirkung | N |
|---|---|---|---|
| various homoeopathic remedies (complex homoeopathy, Melissa officinalis 12C, individualised homoeopa | -- | Positive | 451 |
| None | -- | Positive | -- |
| None | -- | Positive | 51 |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| 200 mg twice daily (400 mg/day) for 3 weeks | 3 weeks | Positive | 100 |
| varies by product and study | -- | Mixed | -- |
| not specified | -- | Positive | -- |
Beste Einnahmezeit: 30-60 minutes before bed
Safety & Side Effects
Gemeldete Nebenwirkungen
- ⚠ Nausea
- ⚠ Abdominal pain
- ⚠ Dizziness
- ⚠ Wheezing (rare allergic reaction)
Bekannte Wechselwirkungen
- ● Thyroid medications — lemon balm may inhibit TSH binding
- ● Sedatives — additive calming effects
- ● Glaucoma medications — may affect intraocular pressure
Tolerierbare Höchstaufnahmemenge: Not established
Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.
Frequently Asked Questions
Does Melissenblatt help with Insomnie?
Based on 22 studies with 933 participants, there is strong evidence from multiple clinical trials that Melissenblatt may support Insomnie management. Our evidence grade is A (Strong Evidence).
How much Melissenblatt should I take for Insomnie?
Studies have used various dosages. A commonly studied range is 300-600 mg extract, before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Melissenblatt?
Reported side effects may include Nausea, Abdominal pain, Dizziness, Wheezing (rare allergic reaction). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Melissenblatt and Insomnie?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 22 peer-reviewed studies with 933 total participants. The overall direction of effect is positive.
Related Evidence
Andere Inhaltsstoffe für Insomnie
Melissenblatt für andere Beschwerden
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