المليسة لـ الأرق
Aبناءً على 21 دراسة (3 meta-analyses, 2 RCTs) بمشاركة 933 مشاركًا إجمالاً. 17/21 دراسة تُظهر تأثيرات إيجابية.
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A
الخلاصة
Lemon balm is well-supported by research as a gentle, natural supplement that may help improve sleep quality for people with insomnia.
- 17 out of 21 studies show positive effects, with Grade A evidence rating
- A 2023 double-blind RCT showed improved sleep and emotional well-being in adults
- Works through GABA-modulating properties confirmed in multiple systematic reviews
- Effective both alone and in combination with other herbs like valerian
Key Study Findings
systematic review
n=451
Double-blind
Effectiveness of Homoeopathic Treatments for Sleep Disorders in Children and Adolescents: A Systematic Review According …
Dose: various homoeopathic remedies (complex homoeopathy, Melissa officinalis 12C, individualised homoeopa
مقابل: Placebo
التأثير: bruxism: ΔVAS -2.36 vs -1.72; enuresis: median -2.4 nights/week
0.05 (bruxism); < 0.04 (enures
Review
Integrative sleep management: from molecular pathways to conventional and herbal treatments.
Dose: None
مقابل: Placebo
التأثير: None
None
Review
n=51
Over-the-counter products for insomnia in adults: A scoping review of randomised controlled trials.
Dose: None
مقابل: Placebo
التأثير: 41/51 studies demonstrated positive effects on insomnia symptoms
None
Review
The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, …
Dose: None
مقابل: Placebo
التأثير: None
None
Review
Therapeutic potential of hypnotic herbal medicines: A comprehensive review.
Dose: None
مقابل: None
Outcome: Sleep quality
التأثير: None
None
المجتمع المدروس: Insomnia patients
randomized controlled trial
n=100
3 weeks
Double-blind
The possible "calming effect" of subchronic supplementation of a standardised phospholipid carrier-based Melissa officinalis L. …
Dose: 200 mg twice daily (400 mg/day) for 3 weeks
مقابل: Placebo
التأثير: significant improvements in all scores (depression, anxiety, stress, positive/negative affect, menta
<0.001
Key Statistics
22
الدراسات
933
المشاركون
↑
Positive
A
التقييم
Referenced Papers
Naunyn-Schmiedeberg's archives of …
2025
4 اقتباسات
Over-the-counter products for insomnia in adults: A scoping review of randomised controlled trials.
Review
Sleep medicine
2025
4 اقتباسات
Molecules (Basel, Switzerland)
2025
2 اقتباسات
Children (Basel, Switzerland)
2025
Phytotherapy research : …
2024
14 اقتباسات
Nutrients
2024
6 اقتباسات
Frontiers in pharmacology
2023
11 اقتباسات
A Perspective on Missing Aspects in Ongoing Purification Research towards Melissa officinalis.
Review
Foods (Basel, Switzerland)
2023
7 اقتباسات
Molecules (Basel, Switzerland)
2022
90 اقتباسات
Nutrients
2021
85 اقتباسات
Combinatorial chemistry & …
2021
16 اقتباسات
Advances in experimental …
2021
7 اقتباسات
Journal of ethnopharmacology
2020
19 اقتباسات
Complementary therapies in …
2019
26 اقتباسات
Assessing insomnia management in community pharmacy setting in Jordan: A simulated patient approach.
Other
PloS one
2019
19 اقتباسات
GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence.
Systematic Review
Phytotherapy research : …
2018
95 اقتباسات
Clinical nutrition ESPEN
2018
78 اقتباسات
Integrative medicine research
2018
18 اقتباسات
Journal of alternative …
2018
15 اقتباسات
Journal of evidence-based …
2017
204 اقتباسات
Electronic physician
2017
102 اقتباسات
Saudi pharmaceutical journal …
2017
19 اقتباسات
Journal of ethnopharmacology
2015
68 اقتباسات
Research in pharmaceutical …
2015
14 اقتباسات
Phytomedicine : international …
2014
30 اقتباسات
Mediterranean journal of …
2011
Medical science monitor …
2009
85 اقتباسات
Revista medico-chirurgicala a …
2008
24 اقتباسات
Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence.
Review
Journal of clinical …
2005
Integrative cancer therapies
2004
59 اقتباسات
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
الجرعات الشائعة
- sleep:
- 300-600 mg extract, before bed
الحد الأعلى: Not established
الجرعات المدروسة في الأبحاث
| الجرعة | المدة | التأثير | ن |
|---|---|---|---|
| various homoeopathic remedies (complex homoeopathy, Melissa officinalis 12C, individualised homoeopa | -- | Positive | 451 |
| None | -- | Positive | -- |
| None | -- | Positive | 51 |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| 200 mg twice daily (400 mg/day) for 3 weeks | 3 weeks | Positive | 100 |
| varies by product and study | -- | Mixed | -- |
| not specified | -- | Positive | -- |
أفضل وقت للتناول: 30-60 minutes before bed
Safety & Side Effects
الآثار الجانبية المُبلّغ عنها
- ⚠ Nausea
- ⚠ Abdominal pain
- ⚠ Dizziness
- ⚠ Wheezing (rare allergic reaction)
التفاعلات المعروفة
- ● Thyroid medications — lemon balm may inhibit TSH binding
- ● Sedatives — additive calming effects
- ● Glaucoma medications — may affect intraocular pressure
الحد الأقصى المسموح به: Not established
استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.
Frequently Asked Questions
Does المليسة help with الأرق?
Based on 22 studies with 933 participants, there is strong evidence from multiple clinical trials that المليسة may support الأرق management. Our evidence grade is A (Strong Evidence).
How much المليسة should I take for الأرق?
Studies have used various dosages. A commonly studied range is 300-600 mg extract, before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of المليسة?
Reported side effects may include Nausea, Abdominal pain, Dizziness, Wheezing (rare allergic reaction). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for المليسة and الأرق?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 22 peer-reviewed studies with 933 total participants. The overall direction of effect is positive.
Related Evidence
مكونات أخرى لـ الأرق
المليسة لحالات أخرى
إخلاء مسؤولية FDA: لم تُقيَّم هذه البيانات من قبل إدارة الغذاء والدواء (FDA). لا تهدف المنتجات والمعلومات الواردة في هذا الموقع إلى تشخيص أو علاج أو شفاء أو الوقاية من أي مرض. تستند تقييمات الأدلة المعروضة إلى تحليلنا للأبحاث المحكّمة المنشورة ولا تُشكّل نصيحة طبية. استشر مقدم الرعاية الصحية دائماً قبل البدء بأي نظام مكملات.