Toronjil para Insomnio
ABasado en 21 estudios (3 meta-analyses, 2 RCTs) con 933 participantes en total. 17/21 estudios muestran efectos positivos.
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A
Conclusión
Lemon balm is well-supported by research as a gentle, natural supplement that may help improve sleep quality for people with insomnia.
- 17 out of 21 studies show positive effects, with Grade A evidence rating
- A 2023 double-blind RCT showed improved sleep and emotional well-being in adults
- Works through GABA-modulating properties confirmed in multiple systematic reviews
- Effective both alone and in combination with other herbs like valerian
Key Study Findings
systematic review
n=451
Double-blind
Effectiveness of Homoeopathic Treatments for Sleep Disorders in Children and Adolescents: A Systematic Review According …
Dose: various homoeopathic remedies (complex homoeopathy, Melissa officinalis 12C, individualised homoeopa
vs: Placebo
Efecto: bruxism: ΔVAS -2.36 vs -1.72; enuresis: median -2.4 nights/week
0.05 (bruxism); < 0.04 (enures
Review
Integrative sleep management: from molecular pathways to conventional and herbal treatments.
Dose: None
vs: Placebo
Efecto: None
None
Review
n=51
Over-the-counter products for insomnia in adults: A scoping review of randomised controlled trials.
Dose: None
vs: Placebo
Efecto: 41/51 studies demonstrated positive effects on insomnia symptoms
None
Review
The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, …
Dose: None
vs: Placebo
Efecto: None
None
Review
Therapeutic potential of hypnotic herbal medicines: A comprehensive review.
Dose: None
vs: None
Outcome: Sleep quality
Efecto: None
None
Población: Insomnia patients
randomized controlled trial
n=100
3 weeks
Double-blind
The possible "calming effect" of subchronic supplementation of a standardised phospholipid carrier-based Melissa officinalis L. …
Dose: 200 mg twice daily (400 mg/day) for 3 weeks
vs: Placebo
Efecto: significant improvements in all scores (depression, anxiety, stress, positive/negative affect, menta
<0.001
Key Statistics
22
Estudios
933
Participantes
↑
Positive
A
Calificación
Referenced Papers
Naunyn-Schmiedeberg's archives of …
2025
4 citas
Over-the-counter products for insomnia in adults: A scoping review of randomised controlled trials.
Review
Sleep medicine
2025
4 citas
Molecules (Basel, Switzerland)
2025
2 citas
Children (Basel, Switzerland)
2025
Phytotherapy research : …
2024
14 citas
Nutrients
2024
6 citas
Frontiers in pharmacology
2023
11 citas
A Perspective on Missing Aspects in Ongoing Purification Research towards Melissa officinalis.
Review
Foods (Basel, Switzerland)
2023
7 citas
Molecules (Basel, Switzerland)
2022
90 citas
Nutrients
2021
85 citas
Combinatorial chemistry & …
2021
16 citas
Advances in experimental …
2021
7 citas
Journal of ethnopharmacology
2020
19 citas
Complementary therapies in …
2019
26 citas
Assessing insomnia management in community pharmacy setting in Jordan: A simulated patient approach.
Other
PloS one
2019
19 citas
GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence.
Systematic Review
Phytotherapy research : …
2018
95 citas
Clinical nutrition ESPEN
2018
78 citas
Integrative medicine research
2018
18 citas
Journal of alternative …
2018
15 citas
Journal of evidence-based …
2017
204 citas
Electronic physician
2017
102 citas
Saudi pharmaceutical journal …
2017
19 citas
Journal of ethnopharmacology
2015
68 citas
Research in pharmaceutical …
2015
14 citas
Phytomedicine : international …
2014
30 citas
Mediterranean journal of …
2011
Medical science monitor …
2009
85 citas
Revista medico-chirurgicala a …
2008
24 citas
Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence.
Review
Journal of clinical …
2005
Integrative cancer therapies
2004
59 citas
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosificaciones de uso común
- sleep:
- 300-600 mg extract, before bed
Límite superior: Not established
Dosificaciones estudiadas en la investigación
| Dosificación | Duración | Efecto | N |
|---|---|---|---|
| various homoeopathic remedies (complex homoeopathy, Melissa officinalis 12C, individualised homoeopa | -- | Positive | 451 |
| None | -- | Positive | -- |
| None | -- | Positive | 51 |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| 200 mg twice daily (400 mg/day) for 3 weeks | 3 weeks | Positive | 100 |
| varies by product and study | -- | Mixed | -- |
| not specified | -- | Positive | -- |
Mejor momento para tomar: 30-60 minutes before bed
Safety & Side Effects
Efectos secundarios reportados
- ⚠ Nausea
- ⚠ Abdominal pain
- ⚠ Dizziness
- ⚠ Wheezing (rare allergic reaction)
Interacciones conocidas
- ● Thyroid medications — lemon balm may inhibit TSH binding
- ● Sedatives — additive calming effects
- ● Glaucoma medications — may affect intraocular pressure
Ingesta máxima tolerable: Not established
Consulte siempre a su profesional de salud antes de comenzar cualquier suplemento.Siempre consulte a su profesional de salud antes de comenzar cualquier suplemento.
Frequently Asked Questions
Does Toronjil help with Insomnio?
Based on 22 studies with 933 participants, there is strong evidence from multiple clinical trials that Toronjil may support Insomnio management. Our evidence grade is A (Strong Evidence).
How much Toronjil should I take for Insomnio?
Studies have used various dosages. A commonly studied range is 300-600 mg extract, before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Toronjil?
Reported side effects may include Nausea, Abdominal pain, Dizziness, Wheezing (rare allergic reaction). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Toronjil and Insomnio?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 22 peer-reviewed studies with 933 total participants. The overall direction of effect is positive.
Related Evidence
Otros ingredientes para Insomnio
Toronjil para otras condiciones
Aviso legal FDA: Estas declaraciones no han sido evaluadas por la Food and Drug Administration. Los productos y la información en este sitio web no están destinados a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. Las calificaciones de evidencia presentadas se basan en nuestro análisis de investigación publicada revisada por pares y no constituyen consejo médico. Siempre consulte a su profesional de salud antes de comenzar cualquier régimen de suplementos.