Erva-cidreira para Insônia
ABaseado em 21 estudos (3 meta-analyses, 2 RCTs) com 933 participantes no total. 17/21 estudos mostram efeitos positivos.
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A
Conclusão
Lemon balm is well-supported by research as a gentle, natural supplement that may help improve sleep quality for people with insomnia.
- 17 out of 21 studies show positive effects, with Grade A evidence rating
- A 2023 double-blind RCT showed improved sleep and emotional well-being in adults
- Works through GABA-modulating properties confirmed in multiple systematic reviews
- Effective both alone and in combination with other herbs like valerian
Key Study Findings
systematic review
n=451
Double-blind
Effectiveness of Homoeopathic Treatments for Sleep Disorders in Children and Adolescents: A Systematic Review According …
Dose: various homoeopathic remedies (complex homoeopathy, Melissa officinalis 12C, individualised homoeopa
vs: Placebo
Efeito: bruxism: ΔVAS -2.36 vs -1.72; enuresis: median -2.4 nights/week
0.05 (bruxism); < 0.04 (enures
Review
Integrative sleep management: from molecular pathways to conventional and herbal treatments.
Dose: None
vs: Placebo
Efeito: None
None
Review
n=51
Over-the-counter products for insomnia in adults: A scoping review of randomised controlled trials.
Dose: None
vs: Placebo
Efeito: 41/51 studies demonstrated positive effects on insomnia symptoms
None
Review
The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, …
Dose: None
vs: Placebo
Efeito: None
None
Review
Therapeutic potential of hypnotic herbal medicines: A comprehensive review.
Dose: None
vs: None
Outcome: Sleep quality
Efeito: None
None
População: Insomnia patients
randomized controlled trial
n=100
3 weeks
Double-blind
The possible "calming effect" of subchronic supplementation of a standardised phospholipid carrier-based Melissa officinalis L. …
Dose: 200 mg twice daily (400 mg/day) for 3 weeks
vs: Placebo
Efeito: significant improvements in all scores (depression, anxiety, stress, positive/negative affect, menta
<0.001
Key Statistics
22
Estudos
933
Participantes
↑
Positive
A
Nota
Referenced Papers
Naunyn-Schmiedeberg's archives of …
2025
4 citações
Over-the-counter products for insomnia in adults: A scoping review of randomised controlled trials.
Review
Sleep medicine
2025
4 citações
Molecules (Basel, Switzerland)
2025
2 citações
Children (Basel, Switzerland)
2025
Phytotherapy research : …
2024
14 citações
Nutrients
2024
6 citações
Frontiers in pharmacology
2023
11 citações
A Perspective on Missing Aspects in Ongoing Purification Research towards Melissa officinalis.
Review
Foods (Basel, Switzerland)
2023
7 citações
Molecules (Basel, Switzerland)
2022
90 citações
Nutrients
2021
85 citações
Combinatorial chemistry & …
2021
16 citações
Advances in experimental …
2021
7 citações
Journal of ethnopharmacology
2020
19 citações
Complementary therapies in …
2019
26 citações
Assessing insomnia management in community pharmacy setting in Jordan: A simulated patient approach.
Other
PloS one
2019
19 citações
GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence.
Systematic Review
Phytotherapy research : …
2018
95 citações
Clinical nutrition ESPEN
2018
78 citações
Integrative medicine research
2018
18 citações
Journal of alternative …
2018
15 citações
Journal of evidence-based …
2017
204 citações
Electronic physician
2017
102 citações
Saudi pharmaceutical journal …
2017
19 citações
Journal of ethnopharmacology
2015
68 citações
Research in pharmaceutical …
2015
14 citações
Phytomedicine : international …
2014
30 citações
Mediterranean journal of …
2011
Medical science monitor …
2009
85 citações
Revista medico-chirurgicala a …
2008
24 citações
Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence.
Review
Journal of clinical …
2005
Integrative cancer therapies
2004
59 citações
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosagens Comumente Utilizadas
- sleep:
- 300-600 mg extract, before bed
Limite superior: Not established
Dosagens Estudadas em Pesquisas
| Dosagem | Duração | Efeito | N |
|---|---|---|---|
| various homoeopathic remedies (complex homoeopathy, Melissa officinalis 12C, individualised homoeopa | -- | Positive | 451 |
| None | -- | Positive | -- |
| None | -- | Positive | 51 |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| 200 mg twice daily (400 mg/day) for 3 weeks | 3 weeks | Positive | 100 |
| varies by product and study | -- | Mixed | -- |
| not specified | -- | Positive | -- |
Melhor horário: 30-60 minutes before bed
Safety & Side Effects
Efeitos Colaterais Relatados
- ⚠ Nausea
- ⚠ Abdominal pain
- ⚠ Dizziness
- ⚠ Wheezing (rare allergic reaction)
Interações Conhecidas
- ● Thyroid medications — lemon balm may inhibit TSH binding
- ● Sedatives — additive calming effects
- ● Glaucoma medications — may affect intraocular pressure
Ingestão máxima tolerável: Not established
Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.
Frequently Asked Questions
Does Erva-cidreira help with Insônia?
Based on 22 studies with 933 participants, there is strong evidence from multiple clinical trials that Erva-cidreira may support Insônia management. Our evidence grade is A (Strong Evidence).
How much Erva-cidreira should I take for Insônia?
Studies have used various dosages. A commonly studied range is 300-600 mg extract, before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Erva-cidreira?
Reported side effects may include Nausea, Abdominal pain, Dizziness, Wheezing (rare allergic reaction). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Erva-cidreira and Insônia?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 22 peer-reviewed studies with 933 total participants. The overall direction of effect is positive.
Related Evidence
Outros ingredientes para Insônia
Erva-cidreira para outras condições
Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.