Skip to main content
SleepCited

Мелисса для Бессонница

A Доказательства Несколько крупных клинических испытаний стабильно демонстрируют значительные преимущества.

На основе 21 исследований (3 meta-analyses, 2 RCTs) с участием 933 участников. 17/21 исследований показывают положительные эффекты.

<\/script>\n
`; }, get iframeSnippet() { const domain = 'sleepcited.com'; const params = 'ingredient\u003Dlemon\u002Dbalm\u0026condition\u003Dinsomnia'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style



      
      
    

Widget powered by . Free, no account required.

A

Итог

Lemon balm is well-supported by research as a gentle, natural supplement that may help improve sleep quality for people with insomnia.

  • 17 out of 21 studies show positive effects, with Grade A evidence rating
  • A 2023 double-blind RCT showed improved sleep and emotional well-being in adults
  • Works through GABA-modulating properties confirmed in multiple systematic reviews
  • Effective both alone and in combination with other herbs like valerian

Key Study Findings

systematic review n=451 Double-blind
Effectiveness of Homoeopathic Treatments for Sleep Disorders in Children and Adolescents: A Systematic Review According …
Dose: various homoeopathic remedies (complex homoeopathy, Melissa officinalis 12C, individualised homoeopa или: Placebo Эффект: bruxism: ΔVAS -2.36 vs -1.72; enuresis: median -2.4 nights/week 0.05 (bruxism); < 0.04 (enures
Review n=51
Over-the-counter products for insomnia in adults: A scoping review of randomised controlled trials.
Dose: None или: Placebo Эффект: 41/51 studies demonstrated positive effects on insomnia symptoms None
Review
Therapeutic potential of hypnotic herbal medicines: A comprehensive review.
Dose: None или: None Outcome: Sleep quality Эффект: None None

Популяция: Insomnia patients

randomized controlled trial n=100 3 weeks Double-blind
The possible "calming effect" of subchronic supplementation of a standardised phospholipid carrier-based Melissa officinalis L. …
Dose: 200 mg twice daily (400 mg/day) for 3 weeks или: Placebo Эффект: significant improvements in all scores (depression, anxiety, stress, positive/negative affect, menta <0.001

Key Statistics

22

Исследования

933

Участники

Positive

A

Оценка

Referenced Papers

Naunyn-Schmiedeberg's archives of … 2025 4 цитирований
Phytotherapy research : … 2024 14 цитирований
Foods (Basel, Switzerland) 2023 7 цитирований
Molecules (Basel, Switzerland) 2022 90 цитирований
Nutrients 2021 85 цитирований
Combinatorial chemistry & … 2021 16 цитирований
Advances in experimental … 2021 7 цитирований
Phytotherapy research : … 2018 95 цитирований
Journal of evidence-based … 2017 204 цитирований
Electronic physician 2017 102 цитирований
Integrative cancer therapies 2004 59 цитирований

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

sleep:
300-600 mg extract, before bed

Верхний предел: Not established

Дозировки, изученные в исследованиях

Дозировка Длительность Эффект N
various homoeopathic remedies (complex homoeopathy, Melissa officinalis 12C, individualised homoeopa -- Positive 451
None -- Positive --
None -- Positive 51
None -- Positive --
None -- Positive --
200 mg twice daily (400 mg/day) for 3 weeks 3 weeks Positive 100
varies by product and study -- Mixed --
not specified -- Positive --

Лучшее время приёма: 30-60 minutes before bed

Safety & Side Effects

Зарегистрированные побочные эффекты

  • Nausea
  • Abdominal pain
  • Dizziness
  • Wheezing (rare allergic reaction)

Известные взаимодействия

  • Thyroid medications — lemon balm may inhibit TSH binding
  • Sedatives — additive calming effects
  • Glaucoma medications — may affect intraocular pressure

Допустимый верхний уровень потребления: Not established

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Мелисса help with Бессонница?
Based on 22 studies with 933 participants, there is strong evidence from multiple clinical trials that Мелисса may support Бессонница management. Our evidence grade is A (Strong Evidence).
How much Мелисса should I take for Бессонница?
Studies have used various dosages. A commonly studied range is 300-600 mg extract, before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Мелисса?
Reported side effects may include Nausea, Abdominal pain, Dizziness, Wheezing (rare allergic reaction). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Мелисса and Бессонница?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 22 peer-reviewed studies with 933 total participants. The overall direction of effect is positive.

References

  1. [1] Yasmina M Ebrahim et al.. Naunyn Schmiedebergs Arch Pharmacol. 2025. Integrative sleep management: from molecular pathways to conventional and herbal treatments. doi:10.1007/s00210-025-04183-y PubMed
  2. [2] Adriana Salame et al.. Sleep Med. 2025. Over-the-counter products for insomnia in adults: A scoping review of randomised controlled trials. doi:10.1016/j.sleep.2025.02.027 PubMed
  3. [3] Kacper Żełabowski et al.. Molecules. 2025. The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, Ramelteon, Agomelatine, and Selected Herbs. doi:10.3390/molecules30183814 PubMed
  4. [4] Kanchan Upreti et al.. Children (Basel). 2025. Effectiveness of Homoeopathic Treatments for Sleep Disorders in Children and Adolescents: A Systematic Review According to the Principles of Evidence-Based … doi:10.3390/children13010045 PubMed
  5. [5] Mahboobeh Ghasemzadeh Rahbardar et al.. Phytother Res. 2024. Therapeutic potential of hypnotic herbal medicines: A comprehensive review. doi:10.1002/ptr.8201 PubMed
  6. [6] Francesco Di Pierro et al.. Nutrients. 2024. Effects of Melissa officinalis Phytosome on Sleep Quality: Results of a Prospective, Double-Blind, Placebo-Controlled, and Cross-Over Study. doi:10.3390/nu16234199 PubMed
  7. [7] Aasiya Bano et al.. Front Pharmacol. 2023. The possible "calming effect" of subchronic supplementation of a standardised phospholipid carrier-based Melissa officinalis L. extract in healthy adults with … doi:10.3389/fphar.2023.1250560 PubMed
  8. [8] Roberto Castro-Muñoz et al.. Foods. 2023. A Perspective on Missing Aspects in Ongoing Purification Research towards Melissa officinalis. doi:10.3390/foods12091916 PubMed
  9. [9] Maša Kenda et al.. Molecules. 2022. Medicinal Plants Used for Anxiety, Depression, or Stress Treatment: An Update. doi:10.3390/molecules27186021 PubMed
  10. [10] Oliviero Bruni et al.. Nutrients. 2021. Herbal Remedies and Their Possible Effect on the GABAergic System and Sleep. doi:10.3390/nu13020530 PubMed
  11. [11] Ruhi Ali et al.. Comb Chem High Throughput Screen. 2021. Nutraceuticals for Sleep Disorders. doi:10.2174/1386207324666210121111446 PubMed
  12. [12] Diana Lelli et al.. Adv Exp Med Biol. 2021. Use of Plant-Derived Natural Products in Sleep Disturbances. doi:10.1007/978-3-030-64872-5_15 PubMed
  13. [13] Dongju Lee et al.. J Ethnopharmacol. 2020. The herbal extract ALS-L1023 from Melissa officinalis alleviates visceral obesity and insulin resistance in obese female C57BL/6J mice. doi:10.1016/j.jep.2020.112646 PubMed
  14. [14] Patrick Lemoine et al.. Complement Ther Med. 2019. A combination of melatonin, vitamin B6 and medicinal plants in the treatment of mild-to-moderate insomnia: A prospective pilot study. doi:10.1016/j.ctim.2019.05.024 PubMed
  15. [15] Mayyada Wazaify et al.. PLoS One. 2019. Assessing insomnia management in community pharmacy setting in Jordan: A simulated patient approach. doi:10.1371/journal.pone.0226076 PubMed
  16. [16] Karen Savage et al.. Phytother Res. 2018. GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence. doi:10.1002/ptr.5940 PubMed
  17. [17] Habib Haybar et al.. Clin Nutr ESPEN. 2018. The effects of Melissa officinalis supplementation on depression, anxiety, stress, and sleep disorder in patients with chronic stable angina. doi:10.1016/j.clnesp.2018.04.015 PubMed
  18. [18] Maryam Ranjbar et al.. Integr Med Res. 2018. Effects of Herbal combination (Melissa officinalis L. and Nepeta menthoides Boiss. & Buhse) on insomnia severity, anxiety and depression in … doi:10.1016/j.imr.2018.08.001 PubMed
  19. [19] Maryam Ranjbar et al.. J Altern Complement Med. 2018. Efficacy of a Combination of Melissa officinalis L. and Nepeta Menthoides Boiss. & Buhse on Insomnia: A Triple-Blind, Randomized Placebo-Controlled … doi:10.1089/acm.2017.0153 PubMed
  20. [20] Sepide Miraj et al.. J Evid Based Complementary Altern Med. 2017. Melissa officinalis L: A Review Study With an Antioxidant Prospective. doi:10.1177/2156587216663433 PubMed
  21. [21] Rahele Kargozar et al.. Electron Physician. 2017. A review of effective herbal medicines in controlling menopausal symptoms. doi:10.19082/5826 PubMed
  22. [22] Nikola M Stojanović et al.. Saudi Pharm J. 2017. Prevalence of self-medication practice with herbal products among non-psychotic psychiatric patients from southeastern Serbia: A cross-sectional study. doi:10.1016/j.jsps.2017.02.002 PubMed
  23. [23] Fatemeh Alijaniha et al.. J Ethnopharmacol. 2015. Heart palpitation relief with Melissa officinalis leaf extract: double blind, randomized, placebo controlled trial of efficacy and safety. doi:10.1016/j.jep.2015.02.007 PubMed
  24. [24] Valiollah Hajhashemi et al.. Res Pharm Sci. 2015. Hypnotic effect of Coriandrum sativum, Ziziphus jujuba, Lavandula angustifolia and Melissa officinalis extracts in mice. PubMed
  25. [25] Jürgen Gromball et al.. Phytomedicine. 2014. Hyperactivity, concentration difficulties and impulsiveness improve during seven weeks' treatment with valerian root and lemon balm extracts in primary school … doi:10.1016/j.phymed.2014.04.004 PubMed
  26. [26] Julien Cases et al.. Med J Nutrition Metab. 2011. Pilot trial of Melissa officinalis L. leaf extract in the treatment of volunteers suffering from mild-to-moderate anxiety disorders and sleep … doi:10.1007/s12349-010-0045-4 PubMed
  27. [27] Benjamin S Weeks. Med Sci Monit. 2009. Formulations of dietary supplements and herbal extracts for relaxation and anxiolytic action: Relarian. PubMed
  28. [28] Monica Hăncianu et al.. Rev Med Chir Soc Med Nat Iasi. 2008. Chemical composition and in vitro antimicrobial activity of essential oil of Melissa officinalis L. from Romania. PubMed
  29. [29] Amy Lynn Meolie et al.. J Clin Sleep Med. 2005. Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence. PubMed
  30. [30] Keith I Block et al.. Integr Cancer Ther. 2004. Safety and efficacy of herbal sedatives in cancer care. doi:10.1177/1534735404265003 PubMed

Отказ от ответственности FDA: Данные утверждения не были оценены Управлением по санитарному надзору за качеством пищевых продуктов и медикаментов (FDA). Продукты и информация на этом сайте не предназначены для диагностики, лечения, излечения или профилактики каких-либо заболеваний. Представленные оценки доказательности основаны на нашем анализе опубликованных рецензируемых исследований и не являются медицинской консультацией. Всегда консультируйтесь с лечащим врачом перед началом приёма любых добавок.