Use of Plant-Derived Natural Products in Sleep Disturbances.

Diana Lelli, Livio Cortese, Claudio Pedone

Review Advances in experimental medicine and biology 2021 7 Zitierungen

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Study Design

Studientyp: narrative review

Intervention: Use of Plant-Derived Natural Products in Sleep Disturbances. varies by product and study
Vergleichsgruppe: Placebo
Wirkungsrichtung: Mixed
Verzerrungsrisiko: Unclear

Abstract

Sleep disorders have a high prevalence both in the general population and especially in specific populations such older adults and oncologic patients. Impacting on quality of life, they often translate in drug prescription, with consequent increased risk of drug-drug interactions and adverse drug reactions. In the last years several products derived from plants have been developed with the aim of treating insomnia with lower risk of side effects. Despite several studies have been performed with this aim, the available evidence is inconclusive, and reviews summarizing the most recent evidences on the effectiveness of plant-derived products in treating insomnia are lacking.This narrative review aims at summarizing the evidences of the mechanism of action, effectiveness and safety of the most commonly used plant-derived products for the treatment of sleep disorders (Valerian, Lemon balm, Passionflower, Chamomile, Hops, and Jujube).