Hops für Menopause-Related Sleep Disturbance

A Evidenz Mehrere große klinische Studien zeigen übereinstimmend signifikante Vorteile.

Based on 8 studies (1 meta-analysis, 3 RCTs) with 2,688 total participants. 6/8 studies show positive effects.

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Fazit

Based on 8 studies (1 meta-analysis, 3 RCTs) with 2,688 total participants. 6/8 studies show positive effects.

Key Study Findings

Randomized Controlled Trial n=40 3 weeks Double-blind

Effects of a Valerian-Hops Extract Combination (Ze 91019) on Sleep Duration and Daytime Cognitive and …

Dose: None vs.: Placebo Outcome: Sleep duration (Fitbit tracker) Wirkung: Mean +21.7 min/night; shortest night +48.7 min 0.019

Population: Adults with occasional sleep problems

Observational Study n=2464

Young adults' knowledge, perceptions and use of cannabidiol products: a mixed-methods study.

Dose: None vs.: None Outcome: CBD knowledge, perceptions, and use Wirkung: None None

Population: US young adults, mean age 24.67y

narrative review

Use of Plant-Derived Natural Products in Sleep Disturbances.

Dose: varies by product and study vs.: Placebo Wirkung: None None

In Vitro

Effect of Valerian/Hop Mixture on Sleep-Related Behaviors in Drosophila melanogaster.

Dose: valerian/hops mixture (20 mg/mL valerian) vs.: control diet Outcome: sleep duration and GABA receptor expression Wirkung: ~20% longer sleeping time None

Population: Drosophila melanogaster (fruit flies)

Systematic Review

Over-the-Counter Agents for the Treatment of Occasional Disturbed Sleep or Transient Insomnia: A Systematic Review …

Dose: None vs.: placebo Outcome: None Wirkung: None None

Population: insomnia patients

Randomized Controlled Trial Double-blind

Treating primary insomnia - the efficacy of valerian and hops.

Dose: None vs.: placebo Outcome: sleep quality Wirkung: None None

Population: None

Key Statistics

Studien

2688

Teilnehmer

↑

Positive

Bewertung

Referenced Papers

Effects of a Valerian-Hops Extract Combination (Ze 91019) on Sleep Duration and Daytime Cognitive and Psychological Parameters in Occasional Insomnia: … RCT

Brain and behavior 2025 1 Zitierungen

Young adults' knowledge, perceptions and use of cannabidiol products: a mixed-methods study. Other

Health education research 2022 14 Zitierungen

Use of Plant-Derived Natural Products in Sleep Disturbances. Review

Advances in experimental … 2021 7 Zitierungen

Effect of Valerian/Hop Mixture on Sleep-Related Behaviors in Drosophila melanogaster. Other

Biological & pharmaceutical … 2017 20 Zitierungen

Over-the-Counter Agents for the Treatment of Occasional Disturbed Sleep or Transient Insomnia: A Systematic Review of Efficacy and Safety. Other

The primary care … 2015 51 Zitierungen

Treating primary insomnia - the efficacy of valerian and hops. Review

Australian family physician 2010 58 Zitierungen

Treating the health, quality of life, and functional impairments in insomnia. Review

Journal of clinical … 2007

Valerian-hops combination and diphenhydramine for treating insomnia: a randomized placebo-controlled clinical trial. RCT

Sleep 2005 187 Zitierungen

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Übliche Dosierungen

sleep:: 300-500 mg extract, 30-60 min before bed; often combined with valerian

Obergrenze: Not formally established

In der Forschung untersuchte Dosierungen

Dosierung	Dauer	Wirkung	N
None	3 weeks	Positive	40
None	--	Neutral	2464
varies by product and study	--	Mixed	--
valerian/hops mixture (20 mg/mL valerian)	--	Positive	--
None	--	Positive	--
None	--	Positive	--
None	--	Positive	--
Valerian 187mg + hops 41.9mg extract, 2 tablets nightly	4 weeks	Positive	184

Beste Einnahmezeit: 30-60 minutes before bed; commonly used with valerian root for synergistic effects

Safety & Side Effects

Gemeldete Nebenwirkungen

⚠ Drowsiness (intended effect)
⚠ Mild estrogenic effects (theoretical from prenylated flavonoids)
⚠ Allergic reactions in hop-sensitive individuals

Bekannte Wechselwirkungen

● Sedatives and CNS depressants — additive effects
● Estrogen-sensitive conditions — hops contain phytoestrogens
● CYP450 substrates — mild enzyme inhibition reported

Tolerierbare Höchstaufnahmemenge: Not formally established

Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.

Frequently Asked Questions

Does Hops help with Menopause-Related Sleep Disturbance?

Based on 8 studies with 2,688 participants, there is strong evidence from multiple clinical trials that Hops may support Menopause-Related Sleep Disturbance management. Our evidence grade is A (Strong Evidence).

How much Hops should I take for Menopause-Related Sleep Disturbance?

Studies have used various dosages. A commonly studied range is 300-500 mg extract, 30-60 min before bed; often combined with valerian. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Hops?

Reported side effects may include Drowsiness (intended effect), Mild estrogenic effects (theoretical from prenylated flavonoids), Allergic reactions in hop-sensitive individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Hops and Menopause-Related Sleep Disturbance?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 8 peer-reviewed studies with 2,688 total participants. The overall direction of effect is positive.

Andere Inhaltsstoffe für Menopause-Related Sleep Disturbance

Saffron (Crocus sativus) D

Hops für andere Beschwerden

Insomnie A Einschlafschwierigkeiten A

Kurzfazit

Based on 8 studies (1 meta-analysis, 3 RCTs) with 2,688 total participants. 6/8 studies show positive effects.

Evidence Strength92%

High confidence

Studienübersicht

RCT (2)Meta (0)Other (6)

Alternativen vergleichen

Sehen Sie, wie andere Inhaltsstoffe bei dieser Beschwerde abschneiden.

Alle Inhaltsstoffe ansehen für Menopause-Related Sleep Disturbance

Mehr erfahren

References

[1] Nathalie Schicktanz et al.. Brain Behav. 2025. Effects of a Valerian-Hops Extract Combination (Ze 91019) on Sleep Duration and Daytime Cognitive and Psychological Parameters in Occasional Insomnia: … doi:10.1002/brb3.70600 PubMed
[2] Christina N Wysota et al.. Health Educ Res. 2022. Young adults' knowledge, perceptions and use of cannabidiol products: a mixed-methods study. doi:10.1093/her/cyac030 PubMed
[3] Diana Lelli et al.. Adv Exp Med Biol. 2021. Use of Plant-Derived Natural Products in Sleep Disturbances. doi:10.1007/978-3-030-64872-5_15 PubMed
[4] Hyeon-Son Choi et al.. Biol Pharm Bull. 2017. Effect of Valerian/Hop Mixture on Sleep-Related Behaviors in Drosophila melanogaster. doi:10.1248/bpb.b17-00262 PubMed
[5] Larry Culpepper et al.. Prim Care Companion CNS Disord. 2015. Over-the-Counter Agents for the Treatment of Occasional Disturbed Sleep or Transient Insomnia: A Systematic Review of Efficacy and Safety. doi:10.4088/PCC.15r01798 PubMed
[6] Shanah Salter et al.. Aust Fam Physician. 2010. Treating primary insomnia - the efficacy of valerian and hops. PubMed
[7] Andrew D Krystal. J Clin Sleep Med. 2007. Treating the health, quality of life, and functional impairments in insomnia. PubMed
[8] Charles M Morin et al.. Sleep. 2005. Valerian-hops combination and diphenhydramine for treating insomnia: a randomized placebo-controlled clinical trial. doi:10.1093/sleep/28.11.1465 PubMed

FDA-Haftungsausschluss: Diese Aussagen wurden nicht von der Food and Drug Administration bewertet. Die Produkte und Informationen auf dieser Website sind nicht dazu bestimmt, Krankheiten zu diagnostizieren, zu behandeln, zu heilen oder zu verhindern. Die dargestellten Evidenzbewertungen basieren auf unserer Analyse veröffentlichter begutachteter Forschung und stellen keine medizinische Beratung dar. Konsultieren Sie immer Ihren Arzt, bevor Sie mit der Einnahme von Nahrungsergänzungsmitteln beginnen.

Hops für Menopause-Related Sleep Disturbance

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Fazit

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

Übliche Dosierungen

In der Forschung untersuchte Dosierungen

Safety & Side Effects

Gemeldete Nebenwirkungen

Bekannte Wechselwirkungen

Frequently Asked Questions

Related Evidence

Andere Inhaltsstoffe für Menopause-Related Sleep Disturbance

Hops für andere Beschwerden

References