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Hops untuk Gangguan Tidur Terkait Menopause

A Bukti Beberapa uji klinis besar secara konsisten menunjukkan manfaat yang signifikan.

Based on 8 studies (1 meta-analysis, 3 RCTs) with 2,688 total participants. 6/8 studies show positive effects.

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A

Kesimpulan

Based on 8 studies (1 meta-analysis, 3 RCTs) with 2,688 total participants. 6/8 studies show positive effects.

Key Study Findings

Randomized Controlled Trial n=40 3 weeks Double-blind
Effects of a Valerian-Hops Extract Combination (Ze 91019) on Sleep Duration and Daytime Cognitive and …
Dose: None vs: Placebo Outcome: Sleep duration (Fitbit tracker) Efek: Mean +21.7 min/night; shortest night +48.7 min 0.019

Populasi: Adults with occasional sleep problems

Observational Study n=2464
Young adults' knowledge, perceptions and use of cannabidiol products: a mixed-methods study.
Dose: None vs: None Outcome: CBD knowledge, perceptions, and use Efek: None None

Populasi: US young adults, mean age 24.67y

narrative review
Use of Plant-Derived Natural Products in Sleep Disturbances.
Dose: varies by product and study vs: Placebo Efek: None None
In Vitro
Effect of Valerian/Hop Mixture on Sleep-Related Behaviors in Drosophila melanogaster.
Dose: valerian/hops mixture (20 mg/mL valerian) vs: control diet Outcome: sleep duration and GABA receptor expression Efek: ~20% longer sleeping time None

Populasi: Drosophila melanogaster (fruit flies)

Systematic Review
Over-the-Counter Agents for the Treatment of Occasional Disturbed Sleep or Transient Insomnia: A Systematic Review …
Dose: None vs: placebo Outcome: None Efek: None None

Populasi: insomnia patients

Randomized Controlled Trial Double-blind
Treating primary insomnia - the efficacy of valerian and hops.
Dose: None vs: placebo Outcome: sleep quality Efek: None None

Populasi: None

Key Statistics

8

Studi

2688

Peserta

Positive

A

Peringkat

Referenced Papers

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

sleep:
300-500 mg extract, 30-60 min before bed; often combined with valerian

Batas atas: Not formally established

Dosis yang Diteliti dalam Penelitian

Dosis Durasi Efek N
None 3 weeks Positive 40
None -- Neutral 2464
varies by product and study -- Mixed --
valerian/hops mixture (20 mg/mL valerian) -- Positive --
None -- Positive --
None -- Positive --
None -- Positive --
Valerian 187mg + hops 41.9mg extract, 2 tablets nightly 4 weeks Positive 184

Waktu terbaik diminum: 30-60 minutes before bed; commonly used with valerian root for synergistic effects

Safety & Side Effects

Efek Samping yang Dilaporkan

  • Drowsiness (intended effect)
  • Mild estrogenic effects (theoretical from prenylated flavonoids)
  • Allergic reactions in hop-sensitive individuals

Interaksi yang Diketahui

  • Sedatives and CNS depressants — additive effects
  • Estrogen-sensitive conditions — hops contain phytoestrogens
  • CYP450 substrates — mild enzyme inhibition reported

Asupan atas yang dapat ditoleransi: Not formally established

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Hops help with Gangguan Tidur Terkait Menopause?
Based on 8 studies with 2,688 participants, there is strong evidence from multiple clinical trials that Hops may support Gangguan Tidur Terkait Menopause management. Our evidence grade is A (Strong Evidence).
How much Hops should I take for Gangguan Tidur Terkait Menopause?
Studies have used various dosages. A commonly studied range is 300-500 mg extract, 30-60 min before bed; often combined with valerian. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Hops?
Reported side effects may include Drowsiness (intended effect), Mild estrogenic effects (theoretical from prenylated flavonoids), Allergic reactions in hop-sensitive individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Hops and Gangguan Tidur Terkait Menopause?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 8 peer-reviewed studies with 2,688 total participants. The overall direction of effect is positive.

Bahan lain untuk Gangguan Tidur Terkait Menopause

References

  1. [1] Nathalie Schicktanz et al.. Brain Behav. 2025. Effects of a Valerian-Hops Extract Combination (Ze 91019) on Sleep Duration and Daytime Cognitive and Psychological Parameters in Occasional Insomnia: … doi:10.1002/brb3.70600 PubMed
  2. [2] Christina N Wysota et al.. Health Educ Res. 2022. Young adults' knowledge, perceptions and use of cannabidiol products: a mixed-methods study. doi:10.1093/her/cyac030 PubMed
  3. [3] Diana Lelli et al.. Adv Exp Med Biol. 2021. Use of Plant-Derived Natural Products in Sleep Disturbances. doi:10.1007/978-3-030-64872-5_15 PubMed
  4. [4] Hyeon-Son Choi et al.. Biol Pharm Bull. 2017. Effect of Valerian/Hop Mixture on Sleep-Related Behaviors in Drosophila melanogaster. doi:10.1248/bpb.b17-00262 PubMed
  5. [5] Larry Culpepper et al.. Prim Care Companion CNS Disord. 2015. Over-the-Counter Agents for the Treatment of Occasional Disturbed Sleep or Transient Insomnia: A Systematic Review of Efficacy and Safety. doi:10.4088/PCC.15r01798 PubMed
  6. [6] Shanah Salter et al.. Aust Fam Physician. 2010. Treating primary insomnia - the efficacy of valerian and hops. PubMed
  7. [7] Andrew D Krystal. J Clin Sleep Med. 2007. Treating the health, quality of life, and functional impairments in insomnia. PubMed
  8. [8] Charles M Morin et al.. Sleep. 2005. Valerian-hops combination and diphenhydramine for treating insomnia: a randomized placebo-controlled clinical trial. doi:10.1093/sleep/28.11.1465 PubMed

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