카모마일 관련 불면증
A 근거 여러 대규모 임상 시험이 일관되게 유의미한 효과를 보여줍니다.총 3,612명의 참여자를 대상으로 한 27건의 연구(메타분석 5건, RCT 4건)에 근거합니다. 27건 중 17건의 연구에서 긍정적인 효과가 나타났습니다.
결론
Chamomile is well-supported by research as a gentle, natural option that may help improve sleep quality for people with insomnia.
- 17 out of 27 studies show positive effects, with Grade A evidence rating
- Both oral chamomile supplements and chamomile aromatherapy have shown benefits
- The active compound apigenin works through GABA receptors to promote sleepiness
- Benefits have been demonstrated across diverse populations including elderly and cancer patients
Key Study Findings
Key Statistics
27
연구
3612
참여자
Positive
등급
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- sleep:
- 270-400 mg extract or 1-3 cups tea
상한량: Not established
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| various medicinal plant oils (topical application) | -- | Positive | -- |
| chamomile oil inhalation for 10 minutes per day for 15 days | 2 weeks | Positive | 80 |
| German chamomile (Matricaria chamomilla) extract | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| varies by supplement | -- | Positive | -- |
| varies | -- | Positive | 772 |
| single essential oil or blended oil massage; specific volumes not reported in abstract | -- | Positive | -- |
권장 복용 시간: 30-60 minutes before bed
Safety & Side Effects
보고된 부작용
- ⚠ Allergic reactions (ragweed family)
- ⚠ Nausea
- ⚠ Drowsiness
알려진 상호작용
- ● Blood thinners (warfarin) — chamomile contains coumarin compounds
- ● CYP1A2 substrates — chamomile may inhibit this enzyme
- ● Sedatives — mild additive effects
일일 최대 섭취 허용량: Not established
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does 카모마일 help with 불면증?
How much 카모마일 should I take for 불면증?
Are there side effects of 카모마일?
How strong is the evidence for 카모마일 and 불면증?
Related Evidence
카모마일 다른 건강 상태에 대한 근거
References
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- [2] Yasmina M Ebrahim et al.. Naunyn Schmiedebergs Arch Pharmacol. 2025. Integrative sleep management: from molecular pathways to conventional and herbal treatments. doi:10.1007/s00210-025-04183-y PubMed
- [3] Vivek Chavda et al.. Maturitas. 2025. A review on essential oils: A potential tonic for mental wellbeing in the aging population? doi:10.1016/j.maturitas.2024.108158 PubMed
- [4] Maryam Mohammadian-Dameski et al.. Avicenna J Phytomed. 2025. Topical application of medicinal plant oils in pediatric-related disorders: A comparative review article based on traditional Persian medicine. doi:10.22038/AJP.2024.24303 PubMed
- [5] Moka Ikeda et al.. Biochem Genet. 2025. German Chamomile (Matricaria chamomilla) Induces Cytochrome P450 Expression Through Increased BMAL1 Protein Expression in Liver Nuclei. doi:10.1007/s10528-025-11260-7 PubMed
- [6] Ji Won Yeom et al.. Psychiatry Investig. 2024. Herbal and Natural Supplements for Improving Sleep: A Literature Review. doi:10.30773/pi.2024.0121 PubMed
- [7] Asma Kazemi et al.. Complement Ther Med. 2024. Effects of chamomile (Matricaria chamomilla L.) on sleep: A systematic review and meta-analysis of clinical trials. doi:10.1016/j.ctim.2024.103071 PubMed
- [8] Fei-Yi Zhao et al.. Front Public Health. 2023. Identifying complementary and alternative medicine recommendations for insomnia treatment and care: a systematic review and critical assessment of comprehensive clinical … doi:10.3389/fpubh.2023.1157419 PubMed
- [9] Kyung-Bok Lee et al.. Biomol Ther (Seoul). 2023. Differences in Neurotransmitters Level as Biomarker on Sleep Effects in Dementia Patients with Insomnia after Essential Oils Treatment. doi:10.4062/biomolther.2023.014 PubMed
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- [11] Sin Yee Lee et al.. Front Pharmacol. 2022. Effect of drying methods on yield, physicochemical properties, and total polyphenol content of chamomile extract powder. doi:10.3389/fphar.2022.1003209 PubMed
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- [13] Diana Lelli et al.. Adv Exp Med Biol. 2021. Use of Plant-Derived Natural Products in Sleep Disturbances. doi:10.1007/978-3-030-64872-5_15 PubMed
- [14] Truong Hong Hieu et al.. Phytother Res. 2019. Therapeutic efficacy and safety of chamomile for state anxiety, generalized anxiety disorder, insomnia, and sleep quality: A systematic review and … doi:10.1002/ptr.6349 PubMed
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- [16] Mohsen Adib-Hajbaghery et al.. Complement Ther Med. 2017. The effects of chamomile extract on sleep quality among elderly people: A clinical trial. doi:10.1016/j.ctim.2017.09.010 PubMed
- [17] Lisa Blackburn et al.. Oncol Nurs Forum. 2017. The Effect of Aromatherapy on Insomnia and Other Common Symptoms Among Patients With Acute Leukemia. doi:10.1188/17.ONF.E185-E193 PubMed
- [18] Matthew J Leach et al.. Sleep Med Rev. 2015. Herbal medicine for insomnia: A systematic review and meta-analysis. doi:10.1016/j.smrv.2014.12.003 PubMed
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- [20] Suzanna M Zick et al.. BMC Complement Altern Med. 2011. Preliminary examination of the efficacy and safety of a standardized chamomile extract for chronic primary insomnia: a randomized placebo-controlled pilot … doi:10.1186/1472-6882-11-78 PubMed
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- [23] David Wheatley. J Psychopharmacol. 2005. Medicinal plants for insomnia: a review of their pharmacology, efficacy and tolerability. doi:10.1177/0269881105053309 PubMed
- [24] Amy Lynn Meolie et al.. J Clin Sleep Med. 2005. Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence. PubMed
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