Manzanilla para Insomnio
ABasado en 27 estudios (5 meta-analyses, 4 RCTs) con 3,612 participantes en total. 17/27 estudios muestran efectos positivos.
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A
Conclusión
Chamomile is well-supported by research as a gentle, natural option that may help improve sleep quality for people with insomnia.
- 17 out of 27 studies show positive effects, with Grade A evidence rating
- Both oral chamomile supplements and chamomile aromatherapy have shown benefits
- The active compound apigenin works through GABA receptors to promote sleepiness
- Benefits have been demonstrated across diverse populations including elderly and cancer patients
Key Study Findings
review
Topical application of medicinal plant oils in pediatric-related disorders: A comparative review article based on …
Dose: various medicinal plant oils (topical application)
vs: Placebo
Efecto: None
None
randomized_controlled_trial
n=80
2 weeks
Effects of chamomile oil inhalation on sleep quality in young adults with insomnia: A randomized …
Dose: chamomile oil inhalation for 10 minutes per day for 15 days
vs: Placebo
Efecto: significant reduction in PSQI and ISI in aromatherapy group vs control (p<0.001 for both between-gro
<0.001 (between-group PSQI and
basic science
German Chamomile (Matricaria chamomilla) Induces Cytochrome P450 Expression Through Increased BMAL1 Protein Expression in Liver …
Dose: German chamomile (Matricaria chamomilla) extract
vs: Placebo
Efecto: None
None
Review
Integrative sleep management: from molecular pathways to conventional and herbal treatments.
Dose: None
vs: Placebo
Efecto: None
None
Review
A review on essential oils: A potential tonic for mental wellbeing in the aging population?
Dose: None
vs: Placebo
Efecto: None
None
narrative review
Herbal and Natural Supplements for Improving Sleep: A Literature Review.
Dose: varies by supplement
vs: Placebo
Efecto: None
None
Key Statistics
27
Estudios
3612
Participantes
↑
Positive
A
Calificación
Referenced Papers
International journal of …
2025
6 citas
Naunyn-Schmiedeberg's archives of …
2025
4 citas
Maturitas
2025
4 citas
Avicenna journal of …
2025
Biochemical genetics
2025
Psychiatry investigation
2024
24 citas
Effects of chamomile (Matricaria chamomilla L.) on sleep: A systematic review and meta-analysis of clinical trials.
Meta-Analysis
Complementary therapies in …
2024
23 citas
Frontiers in public …
2023
13 citas
Biomolecules & therapeutics
2023
7 citas
Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
Meta-Analysis
Pharmacological research
2022
51 citas
Frontiers in pharmacology
2022
31 citas
Combinatorial chemistry & …
2021
16 citas
Advances in experimental …
2021
7 citas
Phytotherapy research : …
2019
62 citas
GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence.
Systematic Review
Phytotherapy research : …
2018
95 citas
Complementary therapies in …
2017
65 citas
The Effect of Aromatherapy on Insomnia and Other Common Symptoms Among Patients With Acute Leukemia.
Other
Oncology nursing forum
2017
58 citas
Sleep medicine reviews
2015
152 citas
The Australian and …
2014
32 citas
BMC complementary and …
2011
112 citas
Molecular medicine reports
2010
398 citas
Sleep medicine
2009
54 citas
Journal of psychopharmacology …
2005
176 citas
Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence.
Review
Journal of clinical …
2005
Integrative cancer therapies
2004
59 citas
Primary care
2002
43 citas
The Journal of …
2000
5 citas
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosificaciones de uso común
- sleep:
- 270-400 mg extract or 1-3 cups tea
Límite superior: Not established
Dosificaciones estudiadas en la investigación
| Dosificación | Duración | Efecto | N |
|---|---|---|---|
| various medicinal plant oils (topical application) | -- | Positive | -- |
| chamomile oil inhalation for 10 minutes per day for 15 days | 2 weeks | Positive | 80 |
| German chamomile (Matricaria chamomilla) extract | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| varies by supplement | -- | Positive | -- |
| varies | -- | Positive | 772 |
| single essential oil or blended oil massage; specific volumes not reported in abstract | -- | Positive | -- |
Mejor momento para tomar: 30-60 minutes before bed
Safety & Side Effects
Efectos secundarios reportados
- ⚠ Allergic reactions (ragweed family)
- ⚠ Nausea
- ⚠ Drowsiness
Interacciones conocidas
- ● Blood thinners (warfarin) — chamomile contains coumarin compounds
- ● CYP1A2 substrates — chamomile may inhibit this enzyme
- ● Sedatives — mild additive effects
Ingesta máxima tolerable: Not established
Consulte siempre a su profesional de salud antes de comenzar cualquier suplemento.Siempre consulte a su profesional de salud antes de comenzar cualquier suplemento.
Frequently Asked Questions
Does Manzanilla help with Insomnio?
Based on 27 studies with 3,612 participants, there is strong evidence from multiple clinical trials that Manzanilla may support Insomnio management. Our evidence grade is A (Strong Evidence).
How much Manzanilla should I take for Insomnio?
Studies have used various dosages. A commonly studied range is 270-400 mg extract or 1-3 cups tea. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Manzanilla?
Reported side effects may include Allergic reactions (ragweed family), Nausea, Drowsiness. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Manzanilla and Insomnio?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 27 peer-reviewed studies with 3,612 total participants. The overall direction of effect is positive.
Related Evidence
Otros ingredientes para Insomnio
Manzanilla para otras condiciones
Aviso legal FDA: Estas declaraciones no han sido evaluadas por la Food and Drug Administration. Los productos y la información en este sitio web no están destinados a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. Las calificaciones de evidencia presentadas se basan en nuestro análisis de investigación publicada revisada por pares y no constituyen consejo médico. Siempre consulte a su profesional de salud antes de comenzar cualquier régimen de suplementos.