カモミール ： 不眠症
A合計3,612名の参加者を対象とした27件の研究（メタアナリシス5件、RCT 4件を含む）に基づく。27件中17件の研究で肯定的な効果が示されている。
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A
結論
Chamomile is well-supported by research as a gentle, natural option that may help improve sleep quality for people with insomnia.
- 17 out of 27 studies show positive effects, with Grade A evidence rating
- Both oral chamomile supplements and chamomile aromatherapy have shown benefits
- The active compound apigenin works through GABA receptors to promote sleepiness
- Benefits have been demonstrated across diverse populations including elderly and cancer patients
Key Study Findings
review
Topical application of medicinal plant oils in pediatric-related disorders: A comparative review article based on …
Dose: various medicinal plant oils (topical application)
vs: Placebo
効果: None
None
randomized_controlled_trial
n=80
2 weeks
Effects of chamomile oil inhalation on sleep quality in young adults with insomnia: A randomized …
Dose: chamomile oil inhalation for 10 minutes per day for 15 days
vs: Placebo
効果: significant reduction in PSQI and ISI in aromatherapy group vs control (p<0.001 for both between-gro
<0.001 (between-group PSQI and
basic science
German Chamomile (Matricaria chamomilla) Induces Cytochrome P450 Expression Through Increased BMAL1 Protein Expression in Liver …
Dose: German chamomile (Matricaria chamomilla) extract
vs: Placebo
効果: None
None
Review
Integrative sleep management: from molecular pathways to conventional and herbal treatments.
Dose: None
vs: Placebo
効果: None
None
Review
A review on essential oils: A potential tonic for mental wellbeing in the aging population?
Dose: None
vs: Placebo
効果: None
None
narrative review
Herbal and Natural Supplements for Improving Sleep: A Literature Review.
Dose: varies by supplement
vs: Placebo
効果: None
None
Key Statistics
27
研究数
3612
参加者数
↑
Positive
A
グレード
Referenced Papers
International journal of …
2025
6 件の引用
Naunyn-Schmiedeberg's archives of …
2025
4 件の引用
Maturitas
2025
4 件の引用
Avicenna journal of …
2025
Biochemical genetics
2025
Psychiatry investigation
2024
24 件の引用
Effects of chamomile (Matricaria chamomilla L.) on sleep: A systematic review and meta-analysis of clinical trials.
Meta-Analysis
Complementary therapies in …
2024
23 件の引用
Frontiers in public …
2023
13 件の引用
Biomolecules & therapeutics
2023
7 件の引用
Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
Meta-Analysis
Pharmacological research
2022
51 件の引用
Frontiers in pharmacology
2022
31 件の引用
Combinatorial chemistry & …
2021
16 件の引用
Advances in experimental …
2021
7 件の引用
Phytotherapy research : …
2019
62 件の引用
GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence.
Systematic Review
Phytotherapy research : …
2018
95 件の引用
Complementary therapies in …
2017
65 件の引用
The Effect of Aromatherapy on Insomnia and Other Common Symptoms Among Patients With Acute Leukemia.
Other
Oncology nursing forum
2017
58 件の引用
Sleep medicine reviews
2015
152 件の引用
The Australian and …
2014
32 件の引用
BMC complementary and …
2011
112 件の引用
Molecular medicine reports
2010
398 件の引用
Sleep medicine
2009
54 件の引用
Journal of psychopharmacology …
2005
176 件の引用
Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence.
Review
Journal of clinical …
2005
Integrative cancer therapies
2004
59 件の引用
Primary care
2002
43 件の引用
The Journal of …
2000
5 件の引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
一般的な使用量
- sleep:
- 270-400 mg extract or 1-3 cups tea
上限量： Not established
研究で検討された用量
| 用量 | 期間 | 効果 | N |
|---|---|---|---|
| various medicinal plant oils (topical application) | -- | Positive | -- |
| chamomile oil inhalation for 10 minutes per day for 15 days | 2 weeks | Positive | 80 |
| German chamomile (Matricaria chamomilla) extract | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| varies by supplement | -- | Positive | -- |
| varies | -- | Positive | 772 |
| single essential oil or blended oil massage; specific volumes not reported in abstract | -- | Positive | -- |
推奨摂取タイミング： 30-60 minutes before bed
Safety & Side Effects
報告されている副作用
- ⚠ Allergic reactions (ragweed family)
- ⚠ Nausea
- ⚠ Drowsiness
既知の相互作用
- ● Blood thinners (warfarin) — chamomile contains coumarin compounds
- ● CYP1A2 substrates — chamomile may inhibit this enzyme
- ● Sedatives — mild additive effects
耐容上限摂取量： Not established
サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
Frequently Asked Questions
Does カモミール help with 不眠症?
Based on 27 studies with 3,612 participants, there is strong evidence from multiple clinical trials that カモミール may support 不眠症 management. Our evidence grade is A (Strong Evidence).
How much カモミール should I take for 不眠症?
Studies have used various dosages. A commonly studied range is 270-400 mg extract or 1-3 cups tea. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of カモミール?
Reported side effects may include Allergic reactions (ragweed family), Nausea, Drowsiness. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for カモミール and 不眠症?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 27 peer-reviewed studies with 3,612 total participants. The overall direction of effect is positive.
Related Evidence
カモミール 他の症状・状態について
FDAに関する免責事項: これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。