Hoa Cúc cho Mất Ngủ
ADựa trên 27 nghiên cứu (5 meta-analyses, 4 RCTs) với 3,612 người tham gia. 17/27 nghiên cứu cho thấy tác động tích cực.
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A
Kết luận
Chamomile is well-supported by research as a gentle, natural option that may help improve sleep quality for people with insomnia.
- 17 out of 27 studies show positive effects, with Grade A evidence rating
- Both oral chamomile supplements and chamomile aromatherapy have shown benefits
- The active compound apigenin works through GABA receptors to promote sleepiness
- Benefits have been demonstrated across diverse populations including elderly and cancer patients
Key Study Findings
review
Topical application of medicinal plant oils in pediatric-related disorders: A comparative review article based on …
Dose: various medicinal plant oils (topical application)
so với: Placebo
Hiệu quả: None
None
randomized_controlled_trial
n=80
2 weeks
Effects of chamomile oil inhalation on sleep quality in young adults with insomnia: A randomized …
Dose: chamomile oil inhalation for 10 minutes per day for 15 days
so với: Placebo
Hiệu quả: significant reduction in PSQI and ISI in aromatherapy group vs control (p<0.001 for both between-gro
<0.001 (between-group PSQI and
basic science
German Chamomile (Matricaria chamomilla) Induces Cytochrome P450 Expression Through Increased BMAL1 Protein Expression in Liver …
Dose: German chamomile (Matricaria chamomilla) extract
so với: Placebo
Hiệu quả: None
None
Review
Integrative sleep management: from molecular pathways to conventional and herbal treatments.
Dose: None
so với: Placebo
Hiệu quả: None
None
Review
A review on essential oils: A potential tonic for mental wellbeing in the aging population?
Dose: None
so với: Placebo
Hiệu quả: None
None
narrative review
Herbal and Natural Supplements for Improving Sleep: A Literature Review.
Dose: varies by supplement
so với: Placebo
Hiệu quả: None
None
Key Statistics
27
Nghiên cứu
3612
Người tham gia
↑
Positive
A
Xếp hạng
Referenced Papers
International journal of …
2025
6 trích dẫn
Naunyn-Schmiedeberg's archives of …
2025
4 trích dẫn
Maturitas
2025
4 trích dẫn
Avicenna journal of …
2025
Biochemical genetics
2025
Psychiatry investigation
2024
24 trích dẫn
Effects of chamomile (Matricaria chamomilla L.) on sleep: A systematic review and meta-analysis of clinical trials.
Meta-Analysis
Complementary therapies in …
2024
23 trích dẫn
Frontiers in public …
2023
13 trích dẫn
Biomolecules & therapeutics
2023
7 trích dẫn
Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
Meta-Analysis
Pharmacological research
2022
51 trích dẫn
Frontiers in pharmacology
2022
31 trích dẫn
Combinatorial chemistry & …
2021
16 trích dẫn
Advances in experimental …
2021
7 trích dẫn
Phytotherapy research : …
2019
62 trích dẫn
GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence.
Systematic Review
Phytotherapy research : …
2018
95 trích dẫn
Complementary therapies in …
2017
65 trích dẫn
The Effect of Aromatherapy on Insomnia and Other Common Symptoms Among Patients With Acute Leukemia.
Other
Oncology nursing forum
2017
58 trích dẫn
Sleep medicine reviews
2015
152 trích dẫn
The Australian and …
2014
32 trích dẫn
BMC complementary and …
2011
112 trích dẫn
Molecular medicine reports
2010
398 trích dẫn
Sleep medicine
2009
54 trích dẫn
Journal of psychopharmacology …
2005
176 trích dẫn
Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence.
Review
Journal of clinical …
2005
Integrative cancer therapies
2004
59 trích dẫn
Primary care
2002
43 trích dẫn
The Journal of …
2000
5 trích dẫn
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Liều lượng thường dùng
- sleep:
- 270-400 mg extract or 1-3 cups tea
Giới hạn trên: Not established
Liều lượng đã nghiên cứu
| Liều lượng | Thời gian | Hiệu quả | N |
|---|---|---|---|
| various medicinal plant oils (topical application) | -- | Positive | -- |
| chamomile oil inhalation for 10 minutes per day for 15 days | 2 weeks | Positive | 80 |
| German chamomile (Matricaria chamomilla) extract | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| varies by supplement | -- | Positive | -- |
| varies | -- | Positive | 772 |
| single essential oil or blended oil massage; specific volumes not reported in abstract | -- | Positive | -- |
Thời điểm dùng tốt nhất: 30-60 minutes before bed
Safety & Side Effects
Tác dụng phụ đã được báo cáo
- ⚠ Allergic reactions (ragweed family)
- ⚠ Nausea
- ⚠ Drowsiness
Tương tác đã biết
- ● Blood thinners (warfarin) — chamomile contains coumarin compounds
- ● CYP1A2 substrates — chamomile may inhibit this enzyme
- ● Sedatives — mild additive effects
Mức hấp thụ tối đa cho phép: Not established
Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.
Frequently Asked Questions
Does Hoa Cúc help with Mất Ngủ?
Based on 27 studies with 3,612 participants, there is strong evidence from multiple clinical trials that Hoa Cúc may support Mất Ngủ management. Our evidence grade is A (Strong Evidence).
How much Hoa Cúc should I take for Mất Ngủ?
Studies have used various dosages. A commonly studied range is 270-400 mg extract or 1-3 cups tea. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Hoa Cúc?
Reported side effects may include Allergic reactions (ragweed family), Nausea, Drowsiness. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Hoa Cúc and Mất Ngủ?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 27 peer-reviewed studies with 3,612 total participants. The overall direction of effect is positive.
Related Evidence
Các thành phần khác cho Mất Ngủ
Hoa Cúc cho các tình trạng khác
Tuyên bố miễn trừ FDA: Các tuyên bố này chưa được Cục Quản lý Thực phẩm và Dược phẩm (FDA) đánh giá. Các sản phẩm và thông tin trên trang web này không nhằm mục đích chẩn đoán, điều trị, chữa bệnh hoặc phòng ngừa bất kỳ bệnh nào. Xếp hạng bằng chứng được trình bày dựa trên phân tích của chúng tôi về nghiên cứu đã bình duyệt được công bố và không cấu thành tư vấn y khoa. Luôn tham khảo ý kiến chuyên gia y tế trước khi bắt đầu bất kỳ chế độ thực phẩm chức năng nào.