カモミール ： 不安に伴う睡眠障害
B エビデンス 少なくとも1件のランダム化試験がこれを支持しており、おおむね一貫した結果が得られています。4件の研究（メタアナリシス2件を含む）に基づく。4件中3件の研究で肯定的な効果が示されている。
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B
結論
Chamomile may help improve sleep when anxiety is keeping you awake, with most studies showing positive effects through its calming GABA-related activity.
- 3 out of 4 studies show positive effects, including 2 meta-analyses
- Works through GABA-modulating pathways that promote relaxation
- Has a long traditional history of use as a calming bedtime tea
- Grade B evidence — promising but would benefit from additional clinical trials
Key Study Findings
Meta-Analysis
Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
Dose: Various medicinal herbs: Silexan, Kava, Ginkgo biloba, Withania somnifera, Galphimia glauca, Passion
vs: Placebo
効果: Silexan MD -3.84 (95% CrI -6.31 to -1.34); Kava MD -2.46 (95% CrI -4.47 to -0.32); Ginkgo biloba MD
None
Key Statistics
4
研究数
--
参加者数
↑
Positive
B
グレード
Referenced Papers
Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
Meta-Analysis
Pharmacological research
2022
51 件の引用
GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence.
Systematic Review
Phytotherapy research : …
2018
95 件の引用
Journal of psychopharmacology …
2005
176 件の引用
Integrative cancer therapies
2004
59 件の引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
一般的な使用量
- sleep:
- 270-400 mg extract or 1-3 cups tea
上限量： Not established
研究で検討された用量
| 用量 | 期間 | 効果 | N |
|---|---|---|---|
| Various medicinal herbs: Silexan, Kava, Ginkgo biloba, Withania somnifera, Galphimia glauca, Passion | -- | Positive | -- |
| None | -- | Positive | -- |
推奨摂取タイミング： 30-60 minutes before bed
Safety & Side Effects
報告されている副作用
- ⚠ Allergic reactions (ragweed family)
- ⚠ Nausea
- ⚠ Drowsiness
既知の相互作用
- ● Blood thinners (warfarin) — chamomile contains coumarin compounds
- ● CYP1A2 substrates — chamomile may inhibit this enzyme
- ● Sedatives — mild additive effects
耐容上限摂取量： Not established
サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
Frequently Asked Questions
Does カモミール help with 不安に伴う睡眠障害?
Based on 4 studies with 0 participants, there is moderate evidence from clinical studies that カモミール may support 不安に伴う睡眠障害 management. Our evidence grade is B (Good Evidence).
How much カモミール should I take for 不安に伴う睡眠障害?
Studies have used various dosages. A commonly studied range is 270-400 mg extract or 1-3 cups tea. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of カモミール?
Reported side effects may include Allergic reactions (ragweed family), Nausea, Drowsiness. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for カモミール and 不安に伴う睡眠障害?
We rate the evidence as Grade B (Good Evidence). This rating is based on 4 peer-reviewed studies with 0 total participants. The overall direction of effect is positive.
Related Evidence
に関する他の成分： 不安に伴う睡眠障害
カモミール 他の症状・状態について
References
- [1] Wenting Zhang et al.. Pharmacol Res. 2022. Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis. doi:10.1016/j.phrs.2022.106204 PubMed
- [2] Karen Savage et al.. Phytother Res. 2018. GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence. doi:10.1002/ptr.5940 PubMed
- [3] David Wheatley. J Psychopharmacol. 2005. Medicinal plants for insomnia: a review of their pharmacology, efficacy and tolerability. doi:10.1177/0269881105053309 PubMed
- [4] Keith I Block et al.. Integr Cancer Ther. 2004. Safety and efficacy of herbal sedatives in cancer care. doi:10.1177/1534735404265003 PubMed
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