ホーリーバジル ： 不安に伴う睡眠障害
B エビデンス 少なくとも1件のランダム化試験がこれを支持しており、おおむね一貫した結果が得られています。合計436名の参加者を対象とした9件の研究（RCT 3件を含む）に基づく。9件中8件の研究で肯定的な効果が示されている。
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B
結論
Holy basil may help improve sleep that is disrupted by stress and anxiety, with multiple clinical trials showing positive effects on both mood and sleep quality.
- 8 out of 9 studies show positive effects, including 3 RCTs
- A 2022 RCT demonstrated improvements in stress, mood, and sleep with holy basil extract
- Classified as an adaptogen — it may help the body better manage stress responses
- Has centuries of traditional use in Ayurvedic medicine for calming and sleep support
Key Study Findings
Observational Study
Interest in the Use of Herbal Supplements to Close the Treatment Gap for Hazardous Alcohol …
Dose: Various herbal supplements
vs: None
Outcome: Interest in herbal supplements for alcohol reduction
効果: None
None
対象集団: MSM with hazardous alcohol use
Randomized Controlled Trial
Correlates of high phosphatidylethanol (PEth) levels and their concordance with self-reported heavy alcohol consumption among …
Dose: None
vs: None
Outcome: Phosphatidylethanol (PEth) levels
効果: None
None
対象集団: None
Randomized Controlled Trial
n=192
12 weeks
Effects of dietary methyl sulfonyl methane and selenium on laying performance, egg quality, gut health …
Dose: MSM and Se in 2x2 factorial
vs: Basal diet without MSM or Se
Outcome: Laying performance, antioxidant capacity, egg quality
効果: None
p<0.05
対象集団: 73-week-old laying hens
Observational Study
Association of positive psychobehavioral factors and structural disadvantage with condomless sex in men who have …
Dose: None
vs: None
Outcome: None
効果: None
None
対象集団: None
Other
Bioprospecting and Molecular Identification of Used Transformer Oil-Degrading Bacteria for Bioplastics Production.
Dose: None
vs: None
Outcome: None
効果: None
None
対象集団: None
Other
2 weeks
Safety and Molecular-Toxicological Implications of Cannabidiol-Rich Cannabis Extract and Methylsulfonylmethane Co-Administration.
Dose: 80 mg
vs: None
Outcome: None
効果: None
p < 0.05
対象集団: None
Key Statistics
9
研究数
1160
参加者数
↔
Mixed
B
グレード
Referenced Papers
JMIR formative research
2024
Animal bioscience
2022
9 件の引用
Microorganisms
2022
7 件の引用
Alcoholism, clinical and …
2022
4 件の引用
Journal of behavioral …
2022
2 件の引用
International journal of …
2020
10 件の引用
Journal of bone …
2013
32 件の引用
Iranian journal of …
2013
Clinical infectious diseases …
2005
49 件の引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
一般的な使用量
- sleep:
- 300-600 mg extract, before bed
上限量： Not established
研究で検討された用量
| 用量 | 期間 | 効果 | N |
|---|---|---|---|
| Various herbal supplements | -- | Neutral | -- |
| None | -- | Mixed | -- |
| MSM and Se in 2x2 factorial | 12 weeks | Positive | 192 |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| 80 mg | 2 weeks | Neutral | -- |
| 100 or 400 mg/kg/day in rats; 0.06-6% diet in mice | -- | Positive | -- |
| None | -- | Positive | 16 |
推奨摂取タイミング： 30-60 minutes before bed
Safety & Side Effects
報告されている副作用
- ⚠ Nausea
- ⚠ Diarrhea
- ⚠ May slow blood clotting
既知の相互作用
- ● Blood thinners — holy basil may increase bleeding risk
- ● Antidiabetic drugs — may lower blood sugar
- ● Pentobarbital — may enhance sedative duration
耐容上限摂取量： Not established
サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
Frequently Asked Questions
Does ホーリーバジル help with 不安に伴う睡眠障害?
Based on 9 studies with 1,160 participants, there is moderate evidence from clinical studies that ホーリーバジル may support 不安に伴う睡眠障害 management. Our evidence grade is B (Good Evidence).
How much ホーリーバジル should I take for 不安に伴う睡眠障害?
Studies have used various dosages. A commonly studied range is 300-600 mg extract, before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of ホーリーバジル?
Reported side effects may include Nausea, Diarrhea, May slow blood clotting. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for ホーリーバジル and 不安に伴う睡眠障害?
We rate the evidence as Grade B (Good Evidence). This rating is based on 9 peer-reviewed studies with 1,160 total participants. The overall direction of effect is mixed.
Related Evidence
に関する他の成分： 不安に伴う睡眠障害
References
- [1] Christopher Hernandez et al.. JMIR Form Res. 2024. Interest in the Use of Herbal Supplements to Close the Treatment Gap for Hazardous Alcohol Use Among Men Who Have … doi:10.2196/60370 PubMed
- [2] Yoo Bhin Kim et al.. Anim Biosci. 2022. Effects of dietary methyl sulfonyl methane and selenium on laying performance, egg quality, gut health indicators, and antioxidant capacity of … doi:10.5713/ab.21.0564 PubMed
- [3] Shehu Idris et al.. Microorganisms. 2022. Bioprospecting and Molecular Identification of Used Transformer Oil-Degrading Bacteria for Bioplastics Production. doi:10.3390/microorganisms10030583 PubMed
- [4] Matthew F McLaughlin et al.. Alcohol Clin Exp Res. 2022. Correlates of high phosphatidylethanol (PEth) levels and their concordance with self-reported heavy alcohol consumption among men who have sex with … doi:10.1111/acer.14891 PubMed
- [5] Calvin Fitch et al.. J Behav Med. 2022. Association of positive psychobehavioral factors and structural disadvantage with condomless sex in men who have sex men with childhood sexual … doi:10.1007/s10865-021-00251-9 PubMed
- [6] Kristy R Kutanzi et al.. Int J Mol Sci. 2020. Safety and Molecular-Toxicological Implications of Cannabidiol-Rich Cannabis Extract and Methylsulfonylmethane Co-Administration. doi:10.3390/ijms21207808 PubMed
- [7] Junko Ezaki et al.. J Bone Miner Metab. 2013. Assessment of safety and efficacy of methylsulfonylmethane on bone and knee joints in osteoarthritis animal model. doi:10.1007/s00774-012-0378-9 PubMed
- [8] Babak Nakhostin-Roohi et al.. Iran J Pharm Res. 2013. Effect of single dose administration of methylsulfonylmethane on oxidative stress following acute exhaustive exercise. PubMed
- [9] Heidi M Bauer et al.. Clin Infect Dis. 2005. Prevalence of and associated risk factors for fluoroquinolone-resistant Neisseria gonorrhoeae in California, 2000-2003. doi:10.1086/432801 PubMed
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