Manjericão sagrado para Problemas de Sono Relacionados à Ansiedade
B Evidências Pelo menos um ensaio aleatorizado apoia esta conclusão, com resultados maioritariamente consistentes.Baseado em 9 estudos (3 RCTs) com 436 participantes no total. 8/9 estudos mostram efeitos positivos.
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B
Conclusão
Holy basil may help improve sleep that is disrupted by stress and anxiety, with multiple clinical trials showing positive effects on both mood and sleep quality.
- 8 out of 9 studies show positive effects, including 3 RCTs
- A 2022 RCT demonstrated improvements in stress, mood, and sleep with holy basil extract
- Classified as an adaptogen — it may help the body better manage stress responses
- Has centuries of traditional use in Ayurvedic medicine for calming and sleep support
Key Study Findings
Observational Study
Interest in the Use of Herbal Supplements to Close the Treatment Gap for Hazardous Alcohol …
Dose: Various herbal supplements
vs: None
Outcome: Interest in herbal supplements for alcohol reduction
Efeito: None
None
População: MSM with hazardous alcohol use
Randomized Controlled Trial
Correlates of high phosphatidylethanol (PEth) levels and their concordance with self-reported heavy alcohol consumption among …
Dose: None
vs: None
Outcome: Phosphatidylethanol (PEth) levels
Efeito: None
None
População: None
Randomized Controlled Trial
n=192
12 weeks
Effects of dietary methyl sulfonyl methane and selenium on laying performance, egg quality, gut health …
Dose: MSM and Se in 2x2 factorial
vs: Basal diet without MSM or Se
Outcome: Laying performance, antioxidant capacity, egg quality
Efeito: None
p<0.05
População: 73-week-old laying hens
Observational Study
Association of positive psychobehavioral factors and structural disadvantage with condomless sex in men who have …
Dose: None
vs: None
Outcome: None
Efeito: None
None
População: None
Other
Bioprospecting and Molecular Identification of Used Transformer Oil-Degrading Bacteria for Bioplastics Production.
Dose: None
vs: None
Outcome: None
Efeito: None
None
População: None
Other
2 weeks
Safety and Molecular-Toxicological Implications of Cannabidiol-Rich Cannabis Extract and Methylsulfonylmethane Co-Administration.
Dose: 80 mg
vs: None
Outcome: None
Efeito: None
p < 0.05
População: None
Key Statistics
9
Estudos
1160
Participantes
↔
Mixed
B
Nota
Referenced Papers
JMIR formative research
2024
Animal bioscience
2022
9 citações
Microorganisms
2022
7 citações
Alcoholism, clinical and …
2022
4 citações
Journal of behavioral …
2022
2 citações
International journal of …
2020
10 citações
Journal of bone …
2013
32 citações
Iranian journal of …
2013
Clinical infectious diseases …
2005
49 citações
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosagens Comumente Utilizadas
- sleep:
- 300-600 mg extract, before bed
Limite superior: Not established
Dosagens Estudadas em Pesquisas
| Dosagem | Duração | Efeito | N |
|---|---|---|---|
| Various herbal supplements | -- | Neutral | -- |
| None | -- | Mixed | -- |
| MSM and Se in 2x2 factorial | 12 weeks | Positive | 192 |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| 80 mg | 2 weeks | Neutral | -- |
| 100 or 400 mg/kg/day in rats; 0.06-6% diet in mice | -- | Positive | -- |
| None | -- | Positive | 16 |
Melhor horário: 30-60 minutes before bed
Safety & Side Effects
Efeitos Colaterais Relatados
- ⚠ Nausea
- ⚠ Diarrhea
- ⚠ May slow blood clotting
Interações Conhecidas
- ● Blood thinners — holy basil may increase bleeding risk
- ● Antidiabetic drugs — may lower blood sugar
- ● Pentobarbital — may enhance sedative duration
Ingestão máxima tolerável: Not established
Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.
Frequently Asked Questions
Does Manjericão sagrado help with Problemas de Sono Relacionados à Ansiedade?
Based on 9 studies with 1,160 participants, there is moderate evidence from clinical studies that Manjericão sagrado may support Problemas de Sono Relacionados à Ansiedade management. Our evidence grade is B (Good Evidence).
How much Manjericão sagrado should I take for Problemas de Sono Relacionados à Ansiedade?
Studies have used various dosages. A commonly studied range is 300-600 mg extract, before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Manjericão sagrado?
Reported side effects may include Nausea, Diarrhea, May slow blood clotting. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Manjericão sagrado and Problemas de Sono Relacionados à Ansiedade?
We rate the evidence as Grade B (Good Evidence). This rating is based on 9 peer-reviewed studies with 1,160 total participants. The overall direction of effect is mixed.
Related Evidence
Outros ingredientes para Problemas de Sono Relacionados à Ansiedade
References
- [1] Christopher Hernandez et al.. JMIR Form Res. 2024. Interest in the Use of Herbal Supplements to Close the Treatment Gap for Hazardous Alcohol Use Among Men Who Have … doi:10.2196/60370 PubMed
- [2] Yoo Bhin Kim et al.. Anim Biosci. 2022. Effects of dietary methyl sulfonyl methane and selenium on laying performance, egg quality, gut health indicators, and antioxidant capacity of … doi:10.5713/ab.21.0564 PubMed
- [3] Shehu Idris et al.. Microorganisms. 2022. Bioprospecting and Molecular Identification of Used Transformer Oil-Degrading Bacteria for Bioplastics Production. doi:10.3390/microorganisms10030583 PubMed
- [4] Matthew F McLaughlin et al.. Alcohol Clin Exp Res. 2022. Correlates of high phosphatidylethanol (PEth) levels and their concordance with self-reported heavy alcohol consumption among men who have sex with … doi:10.1111/acer.14891 PubMed
- [5] Calvin Fitch et al.. J Behav Med. 2022. Association of positive psychobehavioral factors and structural disadvantage with condomless sex in men who have sex men with childhood sexual … doi:10.1007/s10865-021-00251-9 PubMed
- [6] Kristy R Kutanzi et al.. Int J Mol Sci. 2020. Safety and Molecular-Toxicological Implications of Cannabidiol-Rich Cannabis Extract and Methylsulfonylmethane Co-Administration. doi:10.3390/ijms21207808 PubMed
- [7] Junko Ezaki et al.. J Bone Miner Metab. 2013. Assessment of safety and efficacy of methylsulfonylmethane on bone and knee joints in osteoarthritis animal model. doi:10.1007/s00774-012-0378-9 PubMed
- [8] Babak Nakhostin-Roohi et al.. Iran J Pharm Res. 2013. Effect of single dose administration of methylsulfonylmethane on oxidative stress following acute exhaustive exercise. PubMed
- [9] Heidi M Bauer et al.. Clin Infect Dis. 2005. Prevalence of and associated risk factors for fluoroquinolone-resistant Neisseria gonorrhoeae in California, 2000-2003. doi:10.1086/432801 PubMed
Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.