圣罗勒（Holy Basil） 用于 焦虑相关性睡眠问题
B 证据 至少一项随机试验支持这一结论，结果基本一致。基于9项研究（3项RCT），共436名参与者。8/9项研究显示积极效果。
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B
结论
Holy basil may help improve sleep that is disrupted by stress and anxiety, with multiple clinical trials showing positive effects on both mood and sleep quality.
- 8 out of 9 studies show positive effects, including 3 RCTs
- A 2022 RCT demonstrated improvements in stress, mood, and sleep with holy basil extract
- Classified as an adaptogen — it may help the body better manage stress responses
- Has centuries of traditional use in Ayurvedic medicine for calming and sleep support
Key Study Findings
Observational Study
Interest in the Use of Herbal Supplements to Close the Treatment Gap for Hazardous Alcohol …
Dose: Various herbal supplements
vs: None
Outcome: Interest in herbal supplements for alcohol reduction
效果: None
None
研究人群: MSM with hazardous alcohol use
Randomized Controlled Trial
Correlates of high phosphatidylethanol (PEth) levels and their concordance with self-reported heavy alcohol consumption among …
Dose: None
vs: None
Outcome: Phosphatidylethanol (PEth) levels
效果: None
None
研究人群: None
Randomized Controlled Trial
n=192
12 weeks
Effects of dietary methyl sulfonyl methane and selenium on laying performance, egg quality, gut health …
Dose: MSM and Se in 2x2 factorial
vs: Basal diet without MSM or Se
Outcome: Laying performance, antioxidant capacity, egg quality
效果: None
p<0.05
研究人群: 73-week-old laying hens
Observational Study
Association of positive psychobehavioral factors and structural disadvantage with condomless sex in men who have …
Dose: None
vs: None
Outcome: None
效果: None
None
研究人群: None
Other
Bioprospecting and Molecular Identification of Used Transformer Oil-Degrading Bacteria for Bioplastics Production.
Dose: None
vs: None
Outcome: None
效果: None
None
研究人群: None
Other
2 weeks
Safety and Molecular-Toxicological Implications of Cannabidiol-Rich Cannabis Extract and Methylsulfonylmethane Co-Administration.
Dose: 80 mg
vs: None
Outcome: None
效果: None
p < 0.05
研究人群: None
Key Statistics
9
研究数量
1160
受试者
↔
Mixed
B
等级
Referenced Papers
JMIR formative research
2024
Animal bioscience
2022
9 次引用
Microorganisms
2022
7 次引用
Alcoholism, clinical and …
2022
4 次引用
Journal of behavioral …
2022
2 次引用
International journal of …
2020
10 次引用
Journal of bone …
2013
32 次引用
Iranian journal of …
2013
Clinical infectious diseases …
2005
49 次引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
常用剂量
- sleep:
- 300-600 mg extract, before bed
上限： Not established
研究中使用的剂量
| 剂量 | 持续时间 | 效果 | N |
|---|---|---|---|
| Various herbal supplements | -- | Neutral | -- |
| None | -- | Mixed | -- |
| MSM and Se in 2x2 factorial | 12 weeks | Positive | 192 |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| 80 mg | 2 weeks | Neutral | -- |
| 100 or 400 mg/kg/day in rats; 0.06-6% diet in mice | -- | Positive | -- |
| None | -- | Positive | 16 |
最佳服用时间： 30-60 minutes before bed
Safety & Side Effects
已报告的副作用
- ⚠ Nausea
- ⚠ Diarrhea
- ⚠ May slow blood clotting
已知相互作用
- ● Blood thinners — holy basil may increase bleeding risk
- ● Antidiabetic drugs — may lower blood sugar
- ● Pentobarbital — may enhance sedative duration
可耐受最高摄入量： Not established
在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
Frequently Asked Questions
Does 圣罗勒（Holy Basil） help with 焦虑相关性睡眠问题?
Based on 9 studies with 1,160 participants, there is moderate evidence from clinical studies that 圣罗勒（Holy Basil） may support 焦虑相关性睡眠问题 management. Our evidence grade is B (Good Evidence).
How much 圣罗勒（Holy Basil） should I take for 焦虑相关性睡眠问题?
Studies have used various dosages. A commonly studied range is 300-600 mg extract, before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of 圣罗勒（Holy Basil）?
Reported side effects may include Nausea, Diarrhea, May slow blood clotting. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for 圣罗勒（Holy Basil） and 焦虑相关性睡眠问题?
We rate the evidence as Grade B (Good Evidence). This rating is based on 9 peer-reviewed studies with 1,160 total participants. The overall direction of effect is mixed.
Related Evidence
其他成分用于 焦虑相关性睡眠问题
References
- [1] Christopher Hernandez et al.. JMIR Form Res. 2024. Interest in the Use of Herbal Supplements to Close the Treatment Gap for Hazardous Alcohol Use Among Men Who Have … doi:10.2196/60370 PubMed
- [2] Yoo Bhin Kim et al.. Anim Biosci. 2022. Effects of dietary methyl sulfonyl methane and selenium on laying performance, egg quality, gut health indicators, and antioxidant capacity of … doi:10.5713/ab.21.0564 PubMed
- [3] Shehu Idris et al.. Microorganisms. 2022. Bioprospecting and Molecular Identification of Used Transformer Oil-Degrading Bacteria for Bioplastics Production. doi:10.3390/microorganisms10030583 PubMed
- [4] Matthew F McLaughlin et al.. Alcohol Clin Exp Res. 2022. Correlates of high phosphatidylethanol (PEth) levels and their concordance with self-reported heavy alcohol consumption among men who have sex with … doi:10.1111/acer.14891 PubMed
- [5] Calvin Fitch et al.. J Behav Med. 2022. Association of positive psychobehavioral factors and structural disadvantage with condomless sex in men who have sex men with childhood sexual … doi:10.1007/s10865-021-00251-9 PubMed
- [6] Kristy R Kutanzi et al.. Int J Mol Sci. 2020. Safety and Molecular-Toxicological Implications of Cannabidiol-Rich Cannabis Extract and Methylsulfonylmethane Co-Administration. doi:10.3390/ijms21207808 PubMed
- [7] Junko Ezaki et al.. J Bone Miner Metab. 2013. Assessment of safety and efficacy of methylsulfonylmethane on bone and knee joints in osteoarthritis animal model. doi:10.1007/s00774-012-0378-9 PubMed
- [8] Babak Nakhostin-Roohi et al.. Iran J Pharm Res. 2013. Effect of single dose administration of methylsulfonylmethane on oxidative stress following acute exhaustive exercise. PubMed
- [9] Heidi M Bauer et al.. Clin Infect Dis. 2005. Prevalence of and associated risk factors for fluoroquinolone-resistant Neisseria gonorrhoeae in California, 2000-2003. doi:10.1086/432801 PubMed
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