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Fosfatidilserina para Problemas de Sono Relacionados à Ansiedade

D

Baseado em 2 estudos. 2/2 estudos mostram efeitos positivos.

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            D

        

        

            
Conclusão

            
            
There is not enough evidence to determine whether phosphatidylserine helps with anxiety-related sleep problems — the research is too early-stage to draw conclusions.

            
            
            
    
                
                
  • 
                    
                    Only 2 studies available with no reported participant data
                
    • 
                
                
  • 
                    
                    No human clinical trials or RCTs specifically on this use
                
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  • 
                    
                    Theoretical basis exists through stress hormone regulation pathways
                
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                    Much more research is needed before making any recommendations
                
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Key Study Findings





    

        
        

            

                
                    In Vitro
                
                
                
                
            

            
                Laboratory domestication of Lactiplantibacillus plantarum alters some phenotypic traits but causes non-novel genomic impact.
            
            

                
                Dose: L. plantarum JGR2 serial passages
                
                
                vs: Ancestral strain
                
                
                Outcome: Phenotypic and genomic changes
                
                
                Efeito: None
                
                
                None
                
            

            
            
População: In vitro bacterial culture study

            
        

        
        

            

                
                    In Vitro
                
                
                
                
            

            
                Genomic analysis of Burkholderia sp. ISTR5 for biofunneling of lignin-derived compounds.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: None
                
                
                Efeito: None
                
                
                None
                
            

            
            
População: None

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
2

        
Estudos

    

    

        
--

        
Participantes

    

    

        
            
            ↔
            
        
        
Mixed

    

    

        D

        
Nota

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Laboratory domestication of Lactiplantibacillus plantarum alters some phenotypic traits but causes non-novel genomic impact.
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Journal of applied …
                        2024
                        
                        1 citações
                        
                    

                

                
                

                    

                        
                            Genomic analysis of Burkholderia sp. ISTR5 for biofunneling of lignin-derived compounds.
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Biotechnology for biofuels
                        2019
                        
                        57 citações
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Dosagens Comumente Utilizadas

                

                    
                    

                        
sleep:

                        
100-300 mg, evening

                    

                    
                

                
                

                    Limite superior: Not established; studied up to 600 mg/day
                

                
            

            

            
            

                
Dosagens Estudadas em Pesquisas

                

                    

                        
                            

                                Dosagem
                                Duração
                                Efeito
                                N
                            

                        
                        
                            
                            

                                L. plantarum JGR2 serial passages
                                --
                                
                                    
                                    Neutral
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                Melhor horário: With dinner or 1-2 hours before bed
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Efeitos Colaterais Relatados

                    
    
                        
                        
  • 
                            ⚠
                            Insomnia at high doses (paradoxical)
                        
    • 
                        
                        
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                            ⚠
                            GI upset
                        
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  • 
                            ⚠
                            Nausea
                        
    • 
                        
                    

                

                

                
                

                    
Interações Conhecidas

                    
    
                        
                        
  • 
                            ●
                            Blood thinners — phosphatidylserine may have mild anticoagulant effects
                        
    • 
                        
                        
  • 
                            ●
                            Anticholinergic drugs — may affect cholinergic signaling
                        
    • 
                        
                        
  • 
                            ●
                            Alzheimer's medications (cholinesterase inhibitors) — potential interaction
                        
    • 
                        
                    

                

                

                
                

                    

                        Ingestão máxima tolerável: Not established; studied up to 600 mg/day
                    

                

                
            

            

                Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Fosfatidilserina help with Problemas de Sono Relacionados à Ansiedade?
            
        
        

            Based on 2 studies with 0 participants, there is preliminary evidence that needs more research that Fosfatidilserina may support Problemas de Sono Relacionados à Ansiedade management. Our evidence grade is D (Very Early Research).
        

    

    
    

        
            How much Fosfatidilserina should I take for Problemas de Sono Relacionados à Ansiedade?
            
        
        

            Studies have used various dosages. A commonly studied range is 100-300 mg, evening. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Fosfatidilserina?
            
        
        

            Reported side effects may include Insomnia at high doses (paradoxical), GI upset, Nausea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Fosfatidilserina and Problemas de Sono Relacionados à Ansiedade?
            
        
        

            We rate the evidence as Grade D (Very Early Research). This rating is based on 2 peer-reviewed studies with 0 total participants. The overall direction of effect is mixed.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                

                    
Outros ingredientes para Problemas de Sono Relacionados à Ansiedade

                    

                        
                        
                            CBD
                            A

                        
                        
                        
                            Kava
                            A

                        
                        
                        
                            Lavanda
                            A

                        
                        
                        
                            Passiflora
                            A

                        
                        
                        
                            Raiz de valeriana
                            B

                        
                        
                        
                            Manjericão sagrado
                            B

                        
                        
                    

                

                

                
            

        

        

    


    
    












    

        Aviso Legal da FDA:
        Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.