Passiflora para Problemas de Sono Relacionados à Ansiedade
A Evidências Vários grandes ensaios clínicos mostram de forma consistente benefícios significativos.Baseado em 9 estudos (4 meta-analyses) com 2,619 participantes no total. 8/9 estudos mostram efeitos positivos.
<\/script>\n`;
},
get iframeSnippet() {
const domain = 'sleepcited.com';
const params = 'ingredient\u003Dpassionflower\u0026condition\u003Danxiety\u002Drelated\u002Dsleep';
return ``;
},
get activeSnippet() {
return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet;
},
copySnippet() {
navigator.clipboard.writeText(this.activeSnippet).then(() => {
this.copied = true;
setTimeout(() => { this.copied = false; }, 2000);
});
}
}"
@keydown.escape.window="open = false"
@click.outside="open = false">
A
Conclusão
Passionflower is well-supported by research as a natural option that may help improve sleep when anxiety is keeping you awake.
- 8 out of 9 studies (including 4 meta-analyses) show positive effects
- Works through the GABA system — the same brain pathway targeted by anti-anxiety medications
- 2,619 participants across the available research
- Especially relevant for sleep problems driven by anxiety or nervous tension
Key Study Findings
Review
The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, …
Dose: None
vs: Placebo
Efeito: None
None
Meta-Analysis
Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
Dose: Various medicinal herbs: Silexan, Kava, Ginkgo biloba, Withania somnifera, Galphimia glauca, Passion
vs: Placebo
Efeito: Silexan MD -3.84 (95% CrI -6.31 to -1.34); Kava MD -2.46 (95% CrI -4.47 to -0.32); Ginkgo biloba MD
None
Review
Medicinal Plants for Insomnia Related to Anxiety: An Updated Review.
Dose: None
vs: Placebo
Efeito: None
None
Review
Safety and efficacy of herbal sedatives in cancer care.
Dose: None
vs: Placebo
Efeito: None
None
Key Statistics
9
Estudos
2619
Participantes
↑
Positive
A
Nota
Referenced Papers
Molecules (Basel, Switzerland)
2025
2 citações
Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
Meta-Analysis
Pharmacological research
2022
51 citações
Nutrients
2021
85 citações
Planta medica
2021
41 citações
GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence.
Systematic Review
Phytotherapy research : …
2018
95 citações
Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review.
Systematic Review
Nutrition journal
2010
187 citações
Medical science monitor …
2009
85 citações
Journal of psychopharmacology …
2005
176 citações
Integrative cancer therapies
2004
59 citações
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosagens Comumente Utilizadas
- sleep:
- 250-500 mg extract or 1-2 cups tea, before bed
Limite superior: Not established
Dosagens Estudadas em Pesquisas
| Dosagem | Duração | Efeito | N |
|---|---|---|---|
| None | -- | Positive | -- |
| Various medicinal herbs: Silexan, Kava, Ginkgo biloba, Withania somnifera, Galphimia glauca, Passion | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
Melhor horário: 30-60 minutes before bed
Safety & Side Effects
Efeitos Colaterais Relatados
- ⚠ Drowsiness
- ⚠ Dizziness
- ⚠ Confusion at high doses
- ⚠ Nausea
Interações Conhecidas
- ● Sedatives and benzodiazepines — additive CNS depression
- ● Blood thinners — passionflower may increase bleeding risk
- ● MAOIs — passionflower contains harmala alkaloids
Ingestão máxima tolerável: Not established
Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.
Frequently Asked Questions
Does Passiflora help with Problemas de Sono Relacionados à Ansiedade?
Based on 9 studies with 2,619 participants, there is strong evidence from multiple clinical trials that Passiflora may support Problemas de Sono Relacionados à Ansiedade management. Our evidence grade is A (Strong Evidence).
How much Passiflora should I take for Problemas de Sono Relacionados à Ansiedade?
Studies have used various dosages. A commonly studied range is 250-500 mg extract or 1-2 cups tea, before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Passiflora?
Reported side effects may include Drowsiness, Dizziness, Confusion at high doses, Nausea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Passiflora and Problemas de Sono Relacionados à Ansiedade?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 9 peer-reviewed studies with 2,619 total participants. The overall direction of effect is positive.
Related Evidence
Outros ingredientes para Problemas de Sono Relacionados à Ansiedade
Passiflora para outras condições
References
- [1] Kacper Żełabowski et al.. Molecules. 2025. The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, Ramelteon, Agomelatine, and Selected Herbs. doi:10.3390/molecules30183814 PubMed
- [2] Wenting Zhang et al.. Pharmacol Res. 2022. Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis. doi:10.1016/j.phrs.2022.106204 PubMed
- [3] Oliviero Bruni et al.. Nutrients. 2021. Herbal Remedies and Their Possible Effect on the GABAergic System and Sleep. doi:10.3390/nu13020530 PubMed
- [4] Silvia Borrás et al.. Planta Med. 2021. Medicinal Plants for Insomnia Related to Anxiety: An Updated Review. doi:10.1055/a-1510-9826 PubMed
- [5] Karen Savage et al.. Phytother Res. 2018. GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence. doi:10.1002/ptr.5940 PubMed
- [6] Shaheen E Lakhan et al.. Nutr J. 2010. Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review. doi:10.1186/1475-2891-9-42 PubMed
- [7] Benjamin S Weeks. Med Sci Monit. 2009. Formulations of dietary supplements and herbal extracts for relaxation and anxiolytic action: Relarian. PubMed
- [8] David Wheatley. J Psychopharmacol. 2005. Medicinal plants for insomnia: a review of their pharmacology, efficacy and tolerability. doi:10.1177/0269881105053309 PubMed
- [9] Keith I Block et al.. Integr Cancer Ther. 2004. Safety and efficacy of herbal sedatives in cancer care. doi:10.1177/1534735404265003 PubMed
Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.