Passionflower for Anxiety-Related Sleep Problems
ABased on 9 studies (4 meta-analyses) with 2,619 total participants. 8/9 studies show positive effects.
The Bottom Line
Passionflower is well-supported by research as a natural option that may help improve sleep when anxiety is keeping you awake.
- 8 out of 9 studies (including 4 meta-analyses) show positive effects
- Works through the GABA system — the same brain pathway targeted by anti-anxiety medications
- 2,619 participants across the available research
- Especially relevant for sleep problems driven by anxiety or nervous tension
Key Study Findings
Key Statistics
9
Studies
2619
Participants
Positive
Grade
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Commonly Used Dosages
- sleep:
- 250-500 mg extract or 1-2 cups tea, before bed
Upper limit: Not established
Dosages Studied in Research
| Dosage | Duration | Effect | N |
|---|---|---|---|
| None | -- | Positive | -- |
| Various medicinal herbs: Silexan, Kava, Ginkgo biloba, Withania somnifera, Galphimia glauca, Passion | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
Best taken: 30-60 minutes before bed
Safety & Side Effects
Reported Side Effects
- ⚠ Drowsiness
- ⚠ Dizziness
- ⚠ Confusion at high doses
- ⚠ Nausea
Known Interactions
- ● Sedatives and benzodiazepines — additive CNS depression
- ● Blood thinners — passionflower may increase bleeding risk
- ● MAOIs — passionflower contains harmala alkaloids
Tolerable upper intake: Not established
Always consult your healthcare provider before starting any supplement.
Frequently Asked Questions
Does Passionflower help with Anxiety-Related Sleep Problems?
How much Passionflower should I take for Anxiety-Related Sleep Problems?
Are there side effects of Passionflower?
How strong is the evidence for Passionflower and Anxiety-Related Sleep Problems?
Related Evidence
Other ingredients for Anxiety-Related Sleep Problems
Passionflower for other conditions
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.