Passiflora para Insônia
A Evidências Vários grandes ensaios clínicos mostram de forma consistente benefícios significativos.Baseado em 20 estudos (5 meta-analyses, 1 RCT) com 2,820 participantes no total. 15/20 estudos mostram efeitos positivos.
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A
Conclusão
Passionflower is supported by good evidence as an herbal supplement that may help improve overall sleep quality for people with insomnia.
- 20 studies including 5 meta-analyses support passionflower for insomnia
- 75% of studies report positive effects on sleep
- Research suggests it works through GABA pathways to promote relaxation
- Generally considered safe and well-tolerated based on available evidence
Key Study Findings
Review
n=51
Over-the-counter products for insomnia in adults: A scoping review of randomised controlled trials.
Dose: None
vs: Placebo
Efeito: 41/51 studies demonstrated positive effects on insomnia symptoms
None
Review
The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, …
Dose: None
vs: Placebo
Efeito: None
None
Review
Integrative sleep management: from molecular pathways to conventional and herbal treatments.
Dose: None
vs: Placebo
Efeito: None
None
review
Plants with Potential Importance in Supporting the Treatment of Depression: Current Trends, and Research.
Dose: varies by plant and study
vs: Placebo
Efeito: promising results for saffron, turmeric, ginkgo, St. John's wort, passionflower
None
Meta-Analysis
Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
Dose: Various medicinal herbs: Silexan, Kava, Ginkgo biloba, Withania somnifera, Galphimia glauca, Passion
vs: Placebo
Efeito: Silexan MD -3.84 (95% CrI -6.31 to -1.34); Kava MD -2.46 (95% CrI -4.47 to -0.32); Ginkgo biloba MD
None
Review
Medicinal Plants for Insomnia Related to Anxiety: An Updated Review.
Dose: None
vs: Placebo
Efeito: None
None
Key Statistics
20
Estudos
2820
Participantes
↑
Positive
A
Nota
Referenced Papers
Pharmaceuticals (Basel, Switzerland)
2026
Over-the-counter products for insomnia in adults: A scoping review of randomised controlled trials.
Review
Sleep medicine
2025
4 citações
Naunyn-Schmiedeberg's archives of …
2025
4 citações
Molecules (Basel, Switzerland)
2025
2 citações
Pharmaceuticals (Basel, Switzerland)
2024
9 citações
Current neuropharmacology
2024
9 citações
Cureus
2024
Journal of traditional …
2023
24 citações
Systematic review on the anxiolytic and hypnotic effects of flower extracts in in vivo pre-clinical studies published from 2010 to …
Systematic Review
Phytotherapy research : …
2023
14 citações
Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
Meta-Analysis
Pharmacological research
2022
51 citações
Nutrients
2021
85 citações
Planta medica
2021
41 citações
Advances in experimental …
2021
7 citações
Neurochemical research
2021
4 citações
Zhongguo Zhong yao …
2021
3 citações
Passiflora incarnata in Neuropsychiatric Disorders-A Systematic Review.
Systematic Review
Nutrients
2020
56 citações
Archives of microbiology
2020
43 citações
International clinical psychopharmacology
2020
20 citações
Food science & …
2020
12 citações
Journal of chemical …
2019
34 citações
Complementary therapies in …
2019
26 citações
Laboratory animal research
2019
5 citações
GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence.
Systematic Review
Phytotherapy research : …
2018
95 citações
Electronic physician
2017
102 citações
Journal of menopausal …
2017
40 citações
Sleep science (Sao …
2017
32 citações
Phytotherapy research : …
2017
12 citações
Indian journal of …
2013
Journal of ethnopharmacology
2013
Phytotherapy research : …
2011
Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review.
Systematic Review
Nutrition journal
2010
187 citações
Medical science monitor …
2009
85 citações
BMC complementary and …
2007
Journal of psychopharmacology …
2005
176 citações
Prescrire international
2005
2 citações
Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence.
Review
Journal of clinical …
2005
Integrative cancer therapies
2004
59 citações
Addiction biology
2003
Journal of pharmacy …
2003
Primary care
2002
43 citações
Journal of ethnopharmacology
2001
[Nature medicine as intoxicant].
Case Report
Tidsskrift for den …
1997
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosagens Comumente Utilizadas
- sleep:
- 250-500 mg extract or 1-2 cups tea, before bed
Limite superior: Not established
Dosagens Estudadas em Pesquisas
| Dosagem | Duração | Efeito | N |
|---|---|---|---|
| None | -- | Positive | 51 |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| varies by plant and study | -- | Positive | -- |
| Various medicinal herbs: Silexan, Kava, Ginkgo biloba, Withania somnifera, Galphimia glauca, Passion | -- | Positive | -- |
| None | -- | Positive | -- |
| varies by product and study | -- | Mixed | -- |
| Various Passiflora incarnata preparations (doses not specified in abstract) | -- | Positive | -- |
Melhor horário: 30-60 minutes before bed
Safety & Side Effects
Efeitos Colaterais Relatados
- ⚠ Drowsiness
- ⚠ Dizziness
- ⚠ Confusion at high doses
- ⚠ Nausea
Interações Conhecidas
- ● Sedatives and benzodiazepines — additive CNS depression
- ● Blood thinners — passionflower may increase bleeding risk
- ● MAOIs — passionflower contains harmala alkaloids
Ingestão máxima tolerável: Not established
Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.
Frequently Asked Questions
Does Passiflora help with Insônia?
Based on 20 studies with 2,820 participants, there is strong evidence from multiple clinical trials that Passiflora may support Insônia management. Our evidence grade is A (Strong Evidence).
How much Passiflora should I take for Insônia?
Studies have used various dosages. A commonly studied range is 250-500 mg extract or 1-2 cups tea, before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Passiflora?
Reported side effects may include Drowsiness, Dizziness, Confusion at high doses, Nausea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Passiflora and Insônia?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 20 peer-reviewed studies with 2,820 total participants. The overall direction of effect is positive.
Related Evidence
Outros ingredientes para Insônia
Passiflora para outras condições
References
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Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.