西番莲 用于 失眠
A 证据 多项大型临床试验一致显示出显著的益处。基于20项研究（5项荟萃分析、1项RCT），共2,820名参与者。15/20项研究显示积极效果。
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A
结论
Passionflower is supported by good evidence as an herbal supplement that may help improve overall sleep quality for people with insomnia.
- 20 studies including 5 meta-analyses support passionflower for insomnia
- 75% of studies report positive effects on sleep
- Research suggests it works through GABA pathways to promote relaxation
- Generally considered safe and well-tolerated based on available evidence
Key Study Findings
Review
n=51
Over-the-counter products for insomnia in adults: A scoping review of randomised controlled trials.
Dose: None
vs: Placebo
效果: 41/51 studies demonstrated positive effects on insomnia symptoms
None
Review
The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, …
Dose: None
vs: Placebo
效果: None
None
Review
Integrative sleep management: from molecular pathways to conventional and herbal treatments.
Dose: None
vs: Placebo
效果: None
None
review
Plants with Potential Importance in Supporting the Treatment of Depression: Current Trends, and Research.
Dose: varies by plant and study
vs: Placebo
效果: promising results for saffron, turmeric, ginkgo, St. John's wort, passionflower
None
Meta-Analysis
Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
Dose: Various medicinal herbs: Silexan, Kava, Ginkgo biloba, Withania somnifera, Galphimia glauca, Passion
vs: Placebo
效果: Silexan MD -3.84 (95% CrI -6.31 to -1.34); Kava MD -2.46 (95% CrI -4.47 to -0.32); Ginkgo biloba MD
None
Review
Medicinal Plants for Insomnia Related to Anxiety: An Updated Review.
Dose: None
vs: Placebo
效果: None
None
Key Statistics
20
研究数量
2820
受试者
↑
Positive
A
等级
Referenced Papers
Pharmaceuticals (Basel, Switzerland)
2026
Over-the-counter products for insomnia in adults: A scoping review of randomised controlled trials.
Review
Sleep medicine
2025
4 次引用
Naunyn-Schmiedeberg's archives of …
2025
4 次引用
Molecules (Basel, Switzerland)
2025
2 次引用
Pharmaceuticals (Basel, Switzerland)
2024
9 次引用
Current neuropharmacology
2024
9 次引用
Cureus
2024
Journal of traditional …
2023
24 次引用
Systematic review on the anxiolytic and hypnotic effects of flower extracts in in vivo pre-clinical studies published from 2010 to …
Systematic Review
Phytotherapy research : …
2023
14 次引用
Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
Meta-Analysis
Pharmacological research
2022
51 次引用
Nutrients
2021
85 次引用
Planta medica
2021
41 次引用
Advances in experimental …
2021
7 次引用
Neurochemical research
2021
4 次引用
Zhongguo Zhong yao …
2021
3 次引用
Passiflora incarnata in Neuropsychiatric Disorders-A Systematic Review.
Systematic Review
Nutrients
2020
56 次引用
Archives of microbiology
2020
43 次引用
International clinical psychopharmacology
2020
20 次引用
Food science & …
2020
12 次引用
Journal of chemical …
2019
34 次引用
Complementary therapies in …
2019
26 次引用
Laboratory animal research
2019
5 次引用
GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence.
Systematic Review
Phytotherapy research : …
2018
95 次引用
Electronic physician
2017
102 次引用
Journal of menopausal …
2017
40 次引用
Sleep science (Sao …
2017
32 次引用
Phytotherapy research : …
2017
12 次引用
Indian journal of …
2013
Journal of ethnopharmacology
2013
Phytotherapy research : …
2011
Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review.
Systematic Review
Nutrition journal
2010
187 次引用
Medical science monitor …
2009
85 次引用
BMC complementary and …
2007
Journal of psychopharmacology …
2005
176 次引用
Prescrire international
2005
2 次引用
Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence.
Review
Journal of clinical …
2005
Integrative cancer therapies
2004
59 次引用
Addiction biology
2003
Journal of pharmacy …
2003
Primary care
2002
43 次引用
Journal of ethnopharmacology
2001
[Nature medicine as intoxicant].
Case Report
Tidsskrift for den …
1997
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
常用剂量
- sleep:
- 250-500 mg extract or 1-2 cups tea, before bed
上限： Not established
研究中使用的剂量
| 剂量 | 持续时间 | 效果 | N |
|---|---|---|---|
| None | -- | Positive | 51 |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| varies by plant and study | -- | Positive | -- |
| Various medicinal herbs: Silexan, Kava, Ginkgo biloba, Withania somnifera, Galphimia glauca, Passion | -- | Positive | -- |
| None | -- | Positive | -- |
| varies by product and study | -- | Mixed | -- |
| Various Passiflora incarnata preparations (doses not specified in abstract) | -- | Positive | -- |
最佳服用时间： 30-60 minutes before bed
Safety & Side Effects
已报告的副作用
- ⚠ Drowsiness
- ⚠ Dizziness
- ⚠ Confusion at high doses
- ⚠ Nausea
已知相互作用
- ● Sedatives and benzodiazepines — additive CNS depression
- ● Blood thinners — passionflower may increase bleeding risk
- ● MAOIs — passionflower contains harmala alkaloids
可耐受最高摄入量： Not established
在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
Frequently Asked Questions
Does 西番莲 help with 失眠?
Based on 20 studies with 2,820 participants, there is strong evidence from multiple clinical trials that 西番莲 may support 失眠 management. Our evidence grade is A (Strong Evidence).
How much 西番莲 should I take for 失眠?
Studies have used various dosages. A commonly studied range is 250-500 mg extract or 1-2 cups tea, before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of 西番莲?
Reported side effects may include Drowsiness, Dizziness, Confusion at high doses, Nausea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for 西番莲 and 失眠?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 20 peer-reviewed studies with 2,820 total participants. The overall direction of effect is positive.
Related Evidence
西番莲 用于其他健康状况
References
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