西番莲用于失眠

基于20项研究（5项荟萃分析、1项RCT），共2,820名参与者。15/20项研究显示积极效果。

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结论

Passionflower is supported by good evidence as an herbal supplement that may help improve overall sleep quality for people with insomnia.

20 studies including 5 meta-analyses support passionflower for insomnia
75% of studies report positive effects on sleep
Research suggests it works through GABA pathways to promote relaxation
Generally considered safe and well-tolerated based on available evidence

Key Study Findings

Review n=51

Over-the-counter products for insomnia in adults: A scoping review of randomised controlled trials.

Dose: None vs: Placebo 效果: 41/51 studies demonstrated positive effects on insomnia symptoms None

Review

The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, …

Dose: None vs: Placebo 效果: None None

Review

Integrative sleep management: from molecular pathways to conventional and herbal treatments.

Dose: None vs: Placebo 效果: None None

review

Plants with Potential Importance in Supporting the Treatment of Depression: Current Trends, and Research.

Dose: varies by plant and study vs: Placebo 效果: promising results for saffron, turmeric, ginkgo, St. John's wort, passionflower None

Meta-Analysis

Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.

Dose: Various medicinal herbs: Silexan, Kava, Ginkgo biloba, Withania somnifera, Galphimia glauca, Passion vs: Placebo 效果: Silexan MD -3.84 (95% CrI -6.31 to -1.34); Kava MD -2.46 (95% CrI -4.47 to -0.32); Ginkgo biloba MD None

Review

Medicinal Plants for Insomnia Related to Anxiety: An Updated Review.

Dose: None vs: Placebo 效果: None None

Key Statistics

研究数量

2820

受试者

↑

Positive

等级

Referenced Papers

Efficacy and Safety of Herbal Supplements with Anxiolytic, Antidepressant, and Sedative Action: A Review of Clinical Data and Toxicological Risks. Review

Pharmaceuticals (Basel, Switzerland) 2026

Over-the-counter products for insomnia in adults: A scoping review of randomised controlled trials. Review

Sleep medicine 2025 4 次引用

Integrative sleep management: from molecular pathways to conventional and herbal treatments. Review

Naunyn-Schmiedeberg's archives of … 2025 4 次引用

The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, Ramelteon, Agomelatine, and Selected Herbs. Review

Molecules (Basel, Switzerland) 2025 2 次引用

Plants with Potential Importance in Supporting the Treatment of Depression: Current Trends, and Research. Review

Pharmaceuticals (Basel, Switzerland) 2024 9 次引用

Edible Herbal Medicines as an Alternative to Common Medication for Sleep Disorders: A Review Article. Review

Current neuropharmacology 2024 9 次引用

Randomized, Double-Blind, Placebo-Controlled, Clinical Study of Passiflora incarnata in Participants With Stress and Sleep Problems. Other

Cureus 2024

Hydroalcoholic extract of Passiflora incarnata improves the autistic-like behavior and neuronal damage in a valproic acid-induced rat model of autism. Other

Journal of traditional … 2023 24 次引用

Systematic review on the anxiolytic and hypnotic effects of flower extracts in in vivo pre-clinical studies published from 2010 to … Systematic Review

Phytotherapy research : … 2023 14 次引用

Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis. Meta-Analysis

Pharmacological research 2022 51 次引用

Herbal Remedies and Their Possible Effect on the GABAergic System and Sleep. Systematic Review

Nutrients 2021 85 次引用

Medicinal Plants for Insomnia Related to Anxiety: An Updated Review. Review

Planta medica 2021 41 次引用

Use of Plant-Derived Natural Products in Sleep Disturbances. Review

Advances in experimental … 2021 7 次引用

Sintocalmy, a Passiflora incarnata Based Herbal, Attenuates Morphine Withdrawal in Mice. Other

Neurochemical research 2021 4 次引用

[Literature research of Passiflora incarnata and discussion of its traditional Chinese medicine properties]. Other

Zhongguo Zhong yao … 2021 3 次引用

Passiflora incarnata in Neuropsychiatric Disorders-A Systematic Review. Systematic Review

Nutrients 2020 56 次引用

Endophytic fungi from Passiflora incarnata: an antioxidant compound source. Other

Archives of microbiology 2020 43 次引用

Effects of Passiflora incarnata Linnaeus on polysomnographic sleep parameters in subjects with insomnia disorder: a double-blind randomized placebo-controlled study. RCT

International clinical psychopharmacology 2020 20 次引用

Sleep-inducing effect of Passiflora incarnata L. extract by single and repeated oral administration in rodent animals. Other

Food science & … 2020 12 次引用

Improvement in neurogenesis and memory function by administration of Passiflora incarnata L. extract applied to sleep disorder in rodent models. Other

Journal of chemical … 2019 34 次引用

A combination of melatonin, vitamin B6 and medicinal plants in the treatment of mild-to-moderate insomnia: A prospective pilot study. Other

Complementary therapies in … 2019 26 次引用

Chronic oral administration of Passiflora incarnata extract has no abnormal effects on metabolic and behavioral parameters in mice, except to … Other

Laboratory animal research 2019 5 次引用

GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence. Systematic Review

Phytotherapy research : … 2018 95 次引用

A review of effective herbal medicines in controlling menopausal symptoms. Review

Electronic physician 2017 102 次引用

Role Identification of Passiflora Incarnata Linnaeus: A Mini Review. Review

Journal of menopausal … 2017 40 次引用

Effect of a medicinal plant (Passiflora incarnata L) on sleep. Other

Sleep science (Sao … 2017 32 次引用

Standardized Passiflora incarnata L. Extract Reverts the Analgesia Induced by Alcohol Withdrawal in Rats. Other

Phytotherapy research : … 2017 12 次引用

Efficacy and safety of a polyherbal sedative-hypnotic formulation NSF-3 in primary insomnia in comparison to zolpidem: a randomized controlled trial. RCT

Indian journal of … 2013

Passiflora incarnata L.: ethnopharmacology, clinical application, safety and evaluation of clinical trials. Review

Journal of ethnopharmacology 2013

Modulation of the γ-aminobutyric acid (GABA) system by Passiflora incarnata L. Other

Phytotherapy research : … 2011

Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review. Systematic Review

Nutrition journal 2010 187 次引用

Formulations of dietary supplements and herbal extracts for relaxation and anxiolytic action: Relarian. Review

Medical science monitor … 2009 85 次引用

Anticonvulsant effects of aerial parts of Passiflora incarnata extract in mice: involvement of benzodiazepine and opioid receptors. Other

BMC complementary and … 2007

Medicinal plants for insomnia: a review of their pharmacology, efficacy and tolerability. Review

Journal of psychopharmacology … 2005 176 次引用

Management of insomnia: a place for traditional herbal remedies. Other

Prescrire international 2005 2 次引用

Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence. Review

Journal of clinical … 2005

Safety and efficacy of herbal sedatives in cancer care. Review

Integrative cancer therapies 2004 59 次引用

Drug/substance reversal effects of a novel tri-substituted benzoflavone moiety (BZF) isolated from Passiflora incarnata Linn.--a brief perspective. Review

Addiction biology 2003

Attenuation of benzodiazepine dependence in mice by a tri-substituted benzoflavone moiety of Passiflora incarnata Linneaus: a non-habit forming anxiolytic. Other

Journal of pharmacy … 2003

Anxiety, depression, and insomnia. Review

Primary care 2002 43 次引用

Anti-anxiety studies on extracts of Passiflora incarnata Linneaus. Other

Journal of ethnopharmacology 2001

[Nature medicine as intoxicant]. Case Report

Tidsskrift for den … 1997

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

常用剂量

sleep:: 250-500 mg extract or 1-2 cups tea, before bed

上限： Not established

研究中使用的剂量

剂量	持续时间	效果	N
None	--	Positive	51
None	--	Positive	--
None	--	Positive	--
varies by plant and study	--	Positive	--
Various medicinal herbs: Silexan, Kava, Ginkgo biloba, Withania somnifera, Galphimia glauca, Passion	--	Positive	--
None	--	Positive	--
varies by product and study	--	Mixed	--
Various Passiflora incarnata preparations (doses not specified in abstract)	--	Positive	--

最佳服用时间： 30-60 minutes before bed

Safety & Side Effects

已报告的副作用

⚠ Drowsiness
⚠ Dizziness
⚠ Confusion at high doses
⚠ Nausea

已知相互作用

● Sedatives and benzodiazepines — additive CNS depression
● Blood thinners — passionflower may increase bleeding risk
● MAOIs — passionflower contains harmala alkaloids

可耐受最高摄入量： Not established

在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。

Frequently Asked Questions

Does 西番莲 help with 失眠?

Based on 20 studies with 2,820 participants, there is strong evidence from multiple clinical trials that 西番莲 may support 失眠 management. Our evidence grade is A (Strong Evidence).

How much 西番莲 should I take for 失眠?

Studies have used various dosages. A commonly studied range is 250-500 mg extract or 1-2 cups tea, before bed. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of 西番莲?

Reported side effects may include Drowsiness, Dizziness, Confusion at high doses, Nausea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for 西番莲 and 失眠?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 20 peer-reviewed studies with 2,820 total participants. The overall direction of effect is positive.

Related Evidence

其他成分用于失眠

褪黑素（Melatonin） A 缬草根 A CBD（大麻二酚） A Omega-3 脂肪酸 A 色氨酸（Tryptophan） A 维生素 D A

西番莲用于其他健康状况

焦虑相关性睡眠问题 A

快速结论

基于20项研究（5项荟萃分析、1项RCT），共2,820名参与者。15/20项研究显示积极效果。

Evidence Strength92%

High confidence

研究分析

RCT (2)Meta (1)Other (17)

对比替代方案

查看其他成分针对该健康状况的对比结果。

查看所有成分用于失眠

了解更多

FDA 免责声明: 这些声明未经美国食品药品监督管理局（FDA）评估。本网站上的产品和信息无意用于诊断、治疗、治愈或预防任何疾病。所展示的证据等级基于我们对已发表的同行评审研究的分析，不构成医疗建议。在开始任何补充剂方案之前，请务必咨询您的医疗保健提供者。

西番莲 用于 失眠

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结论

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

常用剂量

研究中使用的剂量

Safety & Side Effects

已报告的副作用

已知相互作用

Frequently Asked Questions

Related Evidence

其他成分用于 失眠

西番莲 用于其他健康状况

西番莲用于失眠

其他成分用于失眠

西番莲用于其他健康状况