Valerian Root के लिए चिंता-संबंधी नींद की समस्याएं
B संबंधित साक्ष्य कम से कम एक यादृच्छिक परीक्षण इसका समर्थन करता है, जिसके परिणाम अधिकतर सुसंगत हैं।11 अध्ययनों (4 meta-analyses) पर आधारित। 9/11 अध्ययन सकारात्मक प्रभाव दिखाते हैं।
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B
निष्कर्ष
Valerian root may help improve sleep when anxiety is a contributing factor, supported by mostly positive findings from multiple meta-analyses and reviews.
- 9 out of 11 studies (including 4 meta-analyses) show positive effects
- Research suggests valerian works through the GABA system to promote relaxation
- Long history of traditional use for nervousness and sleep problems
- Participant data not reported for this specific condition grouping
Key Study Findings
Review
The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, …
Dose: None
बनाम: Placebo
प्रभाव: None
None
Meta-Analysis
Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
Dose: Various medicinal herbs: Silexan, Kava, Ginkgo biloba, Withania somnifera, Galphimia glauca, Passion
बनाम: Placebo
प्रभाव: Silexan MD -3.84 (95% CrI -6.31 to -1.34); Kava MD -2.46 (95% CrI -4.47 to -0.32); Ginkgo biloba MD
None
Review
Medicinal Plants for Insomnia Related to Anxiety: An Updated Review.
Dose: None
बनाम: Placebo
प्रभाव: None
None
in vitro / metabolic engineering study
Metabolic engineering of Escherichia coli for production of valerenadiene.
Dose: None
बनाम: Placebo
प्रभाव: highest yield: 62.0 mg/L valerenadiene (19.4 mg/L/OD600)
None
systematic review
[Use of valerian in anxiety and sleep disorders: what is the best evidence?].
Dose: variable valerian root extract doses
बनाम: Placebo
प्रभाव: None
None
In Vitro
Valeriana officinalis root extracts have potent anxiolytic effects in laboratory rats.
Dose: valerian root extract 3 ml/kg; valerenic acid 3 mg/kg; diazepam 1 mg/kg; ethanol 1 ml/kg
बनाम: Placebo
प्रभाव: significant reduction in anxious behavior vs ethanol control
Key Statistics
11
अध्ययन
--
प्रतिभागी
↑
Positive
B
ग्रेड
Referenced Papers
Molecules (Basel, Switzerland)
2025
2 उद्धरण
Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
Meta-Analysis
Pharmacological research
2022
51 उद्धरण
Nutrients
2021
85 उद्धरण
Planta medica
2021
41 उद्धरण
GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence.
Systematic Review
Phytotherapy research : …
2018
95 उद्धरण
Journal of biotechnology
2017
25 उद्धरण
Acta medica portuguesa
2011
21 उद्धरण
Phytomedicine : international …
2010
148 उद्धरण
Medical science monitor …
2009
85 उद्धरण
Journal of psychopharmacology …
2005
176 उद्धरण
Integrative cancer therapies
2004
59 उद्धरण
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
सामान्य रूप से उपयोग की जाने वाली खुराकें
- sleep:
- 300-600 mg standardized extract, 30 min before bed
अधिकतम सीमा: Not established
अनुसंधान में अध्ययन की गई खुराकें
| खुराक | अवधि | प्रभाव | N |
|---|---|---|---|
| None | -- | Positive | -- |
| Various medicinal herbs: Silexan, Kava, Ginkgo biloba, Withania somnifera, Galphimia glauca, Passion | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| variable valerian root extract doses | -- | Mixed | -- |
| valerian root extract 3 ml/kg; valerenic acid 3 mg/kg; diazepam 1 mg/kg; ethanol 1 ml/kg | -- | Positive | -- |
| None | -- | Positive | -- |
सेवन का सर्वोत्तम समय: 30-60 minutes before bed; may require 2-4 weeks for full effect
Safety & Side Effects
रिपोर्ट किए गए दुष्प्रभाव
- ⚠ Headache
- ⚠ Dizziness
- ⚠ GI upset
- ⚠ Morning grogginess
- ⚠ Vivid dreams
ज्ञात अंतःक्रियाएँ
- ● Sedatives and alcohol — additive CNS depression
- ● CYP3A4-metabolized drugs — valerian may inhibit this enzyme
- ● Benzodiazepines — potential additive GABA effects
सहनीय अधिकतम सेवन: Not established
कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।
Frequently Asked Questions
Does Valerian Root help with चिंता-संबंधी नींद की समस्याएं?
Based on 11 studies with 0 participants, there is moderate evidence from clinical studies that Valerian Root may support चिंता-संबंधी नींद की समस्याएं management. Our evidence grade is B (Good Evidence).
How much Valerian Root should I take for चिंता-संबंधी नींद की समस्याएं?
Studies have used various dosages. A commonly studied range is 300-600 mg standardized extract, 30 min before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Valerian Root?
Reported side effects may include Headache, Dizziness, GI upset, Morning grogginess. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Valerian Root and चिंता-संबंधी नींद की समस्याएं?
We rate the evidence as Grade B (Good Evidence). This rating is based on 11 peer-reviewed studies with 0 total participants. The overall direction of effect is positive.
Related Evidence
इसके लिए अन्य सामग्री चिंता-संबंधी नींद की समस्याएं
Valerian Root अन्य स्वास्थ्य स्थितियों के लिए
References
- [1] Kacper Żełabowski et al.. Molecules. 2025. The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, Ramelteon, Agomelatine, and Selected Herbs. doi:10.3390/molecules30183814 PubMed
- [2] Wenting Zhang et al.. Pharmacol Res. 2022. Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis. doi:10.1016/j.phrs.2022.106204 PubMed
- [3] Oliviero Bruni et al.. Nutrients. 2021. Herbal Remedies and Their Possible Effect on the GABAergic System and Sleep. doi:10.3390/nu13020530 PubMed
- [4] Silvia Borrás et al.. Planta Med. 2021. Medicinal Plants for Insomnia Related to Anxiety: An Updated Review. doi:10.1055/a-1510-9826 PubMed
- [5] Karen Savage et al.. Phytother Res. 2018. GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence. doi:10.1002/ptr.5940 PubMed
- [6] S Eric Nybo et al.. J Biotechnol. 2017. Metabolic engineering of Escherichia coli for production of valerenadiene. doi:10.1016/j.jbiotec.2017.10.004 PubMed
- [7] Ana Nunes et al.. Acta Med Port. 2011. [Use of valerian in anxiety and sleep disorders: what is the best evidence?]. PubMed
- [8] K Murphy et al.. Phytomedicine. 2010. Valeriana officinalis root extracts have potent anxiolytic effects in laboratory rats. doi:10.1016/j.phymed.2009.10.020 PubMed
- [9] Benjamin S Weeks. Med Sci Monit. 2009. Formulations of dietary supplements and herbal extracts for relaxation and anxiolytic action: Relarian. PubMed
- [10] David Wheatley. J Psychopharmacol. 2005. Medicinal plants for insomnia: a review of their pharmacology, efficacy and tolerability. doi:10.1177/0269881105053309 PubMed
- [11] Keith I Block et al.. Integr Cancer Ther. 2004. Safety and efficacy of herbal sedatives in cancer care. doi:10.1177/1534735404265003 PubMed
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