Akar Valerian untuk Masalah Tidur Terkait Kecemasan

Berdasarkan 11 studi (4 meta-analyses). 9/11 studi menunjukkan efek positif.

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Kesimpulan

Valerian root may help improve sleep when anxiety is a contributing factor, supported by mostly positive findings from multiple meta-analyses and reviews.

9 out of 11 studies (including 4 meta-analyses) show positive effects
Research suggests valerian works through the GABA system to promote relaxation
Long history of traditional use for nervousness and sleep problems
Participant data not reported for this specific condition grouping

Key Study Findings

Review

The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, …

Dose: None vs: Placebo Efek: None None

Meta-Analysis

Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.

Dose: Various medicinal herbs: Silexan, Kava, Ginkgo biloba, Withania somnifera, Galphimia glauca, Passion vs: Placebo Efek: Silexan MD -3.84 (95% CrI -6.31 to -1.34); Kava MD -2.46 (95% CrI -4.47 to -0.32); Ginkgo biloba MD None

Review

Medicinal Plants for Insomnia Related to Anxiety: An Updated Review.

Dose: None vs: Placebo Efek: None None

in vitro / metabolic engineering study

Metabolic engineering of Escherichia coli for production of valerenadiene.

Dose: None vs: Placebo Efek: highest yield: 62.0 mg/L valerenadiene (19.4 mg/L/OD600) None

systematic review

[Use of valerian in anxiety and sleep disorders: what is the best evidence?].

Dose: variable valerian root extract doses vs: Placebo Efek: None None

In Vitro

Valeriana officinalis root extracts have potent anxiolytic effects in laboratory rats.

Dose: valerian root extract 3 ml/kg; valerenic acid 3 mg/kg; diazepam 1 mg/kg; ethanol 1 ml/kg vs: Placebo Efek: significant reduction in anxious behavior vs ethanol control

Key Statistics

Studi

Peserta

↑

Positive

Peringkat

Referenced Papers

The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, Ramelteon, Agomelatine, and Selected Herbs. Review

Molecules (Basel, Switzerland) 2025 2 sitasi

Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis. Meta-Analysis

Pharmacological research 2022 51 sitasi

Herbal Remedies and Their Possible Effect on the GABAergic System and Sleep. Systematic Review

Nutrients 2021 85 sitasi

Medicinal Plants for Insomnia Related to Anxiety: An Updated Review. Review

Planta medica 2021 41 sitasi

GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence. Systematic Review

Phytotherapy research : … 2018 95 sitasi

Metabolic engineering of Escherichia coli for production of valerenadiene. Other

Journal of biotechnology 2017 25 sitasi

[Use of valerian in anxiety and sleep disorders: what is the best evidence?]. Review

Acta medica portuguesa 2011 21 sitasi

Valeriana officinalis root extracts have potent anxiolytic effects in laboratory rats. Other

Phytomedicine : international … 2010 148 sitasi

Formulations of dietary supplements and herbal extracts for relaxation and anxiolytic action: Relarian. Review

Medical science monitor … 2009 85 sitasi

Medicinal plants for insomnia: a review of their pharmacology, efficacy and tolerability. Review

Journal of psychopharmacology … 2005 176 sitasi

Safety and efficacy of herbal sedatives in cancer care. Review

Integrative cancer therapies 2004 59 sitasi

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

sleep:: 300-600 mg standardized extract, 30 min before bed

Batas atas: Not established

Dosis yang Diteliti dalam Penelitian

Dosis	Durasi	Efek	N
None	--	Positive	--
Various medicinal herbs: Silexan, Kava, Ginkgo biloba, Withania somnifera, Galphimia glauca, Passion	--	Positive	--
None	--	Positive	--
None	--	Positive	--
variable valerian root extract doses	--	Mixed	--
valerian root extract 3 ml/kg; valerenic acid 3 mg/kg; diazepam 1 mg/kg; ethanol 1 ml/kg	--	Positive	--
None	--	Positive	--

Waktu terbaik diminum: 30-60 minutes before bed; may require 2-4 weeks for full effect

Safety & Side Effects

Efek Samping yang Dilaporkan

⚠ Headache
⚠ Dizziness
⚠ GI upset
⚠ Morning grogginess
⚠ Vivid dreams

Interaksi yang Diketahui

● Sedatives and alcohol — additive CNS depression
● CYP3A4-metabolized drugs — valerian may inhibit this enzyme
● Benzodiazepines — potential additive GABA effects

Asupan atas yang dapat ditoleransi: Not established

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Akar Valerian help with Masalah Tidur Terkait Kecemasan?

Based on 11 studies with 0 participants, there is moderate evidence from clinical studies that Akar Valerian may support Masalah Tidur Terkait Kecemasan management. Our evidence grade is B (Good Evidence).

How much Akar Valerian should I take for Masalah Tidur Terkait Kecemasan?

Studies have used various dosages. A commonly studied range is 300-600 mg standardized extract, 30 min before bed. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Akar Valerian?

Reported side effects may include Headache, Dizziness, GI upset, Morning grogginess. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Akar Valerian and Masalah Tidur Terkait Kecemasan?

We rate the evidence as Grade B (Good Evidence). This rating is based on 11 peer-reviewed studies with 0 total participants. The overall direction of effect is positive.

Related Evidence

Bahan lain untuk Masalah Tidur Terkait Kecemasan

CBD A Kava A Lavender A Passionflower A Kemangi Suci B GABA B

Akar Valerian untuk kondisi lain

Insomnia A Kesulitan Onset Tidur B

Kesimpulan Singkat

Berdasarkan 11 studi (4 meta-analyses). 9/11 studi menunjukkan efek positif.

Evidence Strength72%

High confidence

Rincian Studi

RCT (0)Meta (1)Other (10)

Bandingkan Alternatif

Lihat bagaimana bahan lain dibandingkan untuk kondisi ini.

Lihat semua bahan untuk Masalah Tidur Terkait Kecemasan

Pelajari Lebih Lanjut

Penafian FDA: Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.