Lavender untuk Masalah Tidur Terkait Kecemasan
A Bukti Beberapa uji klinis besar secara konsisten menunjukkan manfaat yang signifikan.Berdasarkan 11 studi (2 meta-analyses, 2 RCTs) dengan 390 peserta secara total. 9/11 studi menunjukkan efek positif.
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A
Kesimpulan
Lavender, especially in oral supplement form (Silexan), is well-supported by research as a natural option that may improve sleep by easing anxiety.
- 9 out of 11 studies show positive effects, earning a Grade A evidence rating
- Silexan (oral lavender oil) has been tested in multiple RCTs for anxiety-related sleep problems
- Works through both GABAergic brain pathways and calming aromatherapy effects
- A 2022 meta-analysis confirmed that Silexan's sleep benefits are mediated by anxiety reduction
Key Study Findings
Review
The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, …
Dose: None
vs: Placebo
Efek: None
None
In Vitro
Lavender essential oil fractions alleviate sleep disorders induced by the combination of anxiety and caffeine …
Dose: Lavender essential oil fractions 3% (v/v) via inhalation
vs: Placebo
Efek: Lavender essential oil and fractions ameliorated sleep disturbances induced by anxiety and caffeine;
None
narrative review with meta-analysis element
Effect of anxiolytic drug silexan on sleep - a narrative review.
Dose: 80 mg/day (standard dose in reviewed trials)
vs: Placebo
Efek: significant improvement in insomnia item of HAM-A; mediation analysis: >98% of sleep effect mediated
statistically significant (exa
animal study
Characterization of pharmaco-EEG fingerprint and sleep-wake profiles of Lavandula angustifolia Mill. essential oil inhalation and …
Dose: Lavandula angustifolia essential oil 200 μL continuous inhalation; diazepam 10 mg/kg i.p. (comparato
vs: Placebo
Efek: Lavender EO significantly decreased wake episodes and REM sleep latency; diazepam more strongly redu
None
Randomized Controlled Trial
n=212
10 weeks
Double-blind
Beneficial effects of Silexan on sleep are mediated by its anxiolytic effect.
Dose: Silexan 80 mg/day
vs: Placebo
Efek: 98.4% of Silexan's total effect on disturbed sleep mediated by anxiolytic effect; indirect effect ra
HAMA: p < 0.001; PSQI: p = 0.0
systematic review
Effectiveness of Silexan oral lavender essential oil compared to inhaled lavender essential oil aromatherapy for …
Dose: any dose or duration
vs: Placebo
Efek: no studies met inclusion criteria
None
Key Statistics
11
Studi
390
Peserta
↑
Positive
A
Peringkat
Referenced Papers
Molecules (Basel, Switzerland)
2025
2 sitasi
Journal of ethnopharmacology
2023
34 sitasi
The world journal …
2022
9 sitasi
Nutrients
2021
85 sitasi
Journal of ethnopharmacology
2021
16 sitasi
Journal of psychiatric …
2019
32 sitasi
Effectiveness of Silexan oral lavender essential oil compared to inhaled lavender essential oil aromatherapy for sleep in adults: a systematic …
Systematic Review
JBI database of …
2018
8 sitasi
European neuropsychopharmacology : …
2015
84 sitasi
Complementary therapies in …
2014
40 sitasi
Journal of psychopharmacology …
2005
176 sitasi
Integrative cancer therapies
2004
59 sitasi
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosis yang Umum Digunakan
- sleep:
- 80-160 mg Silexan (oral) or aromatherapy
Batas atas: Not established for oral; external use generally safe
Dosis yang Diteliti dalam Penelitian
| Dosis | Durasi | Efek | N |
|---|---|---|---|
| None | -- | Positive | -- |
| Lavender essential oil fractions 3% (v/v) via inhalation | -- | Positive | -- |
| 80 mg/day (standard dose in reviewed trials) | -- | Positive | -- |
| Lavandula angustifolia essential oil 200 μL continuous inhalation; diazepam 10 mg/kg i.p. (comparato | -- | Positive | -- |
| Silexan 80 mg/day | 10 weeks | Positive | 212 |
| any dose or duration | -- | Neutral | -- |
| 80 mg/day | 10 weeks | Positive | 170 |
| Lasea (lavender oil capsules) 80 mg; dosage details not specified | -- | Positive | 8 |
Waktu terbaik diminum: 30-60 minutes before bed (oral); at bedtime (aromatherapy)
Safety & Side Effects
Efek Samping yang Dilaporkan
- ⚠ GI upset (oral form)
- ⚠ Headache
- ⚠ Constipation
- ⚠ Increased appetite
Interaksi yang Diketahui
- ● Sedatives — additive drowsiness with oral lavender
- ● Blood pressure medications — lavender may lower blood pressure
Asupan atas yang dapat ditoleransi: Not established for oral; external use generally safe
Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.
Frequently Asked Questions
Does Lavender help with Masalah Tidur Terkait Kecemasan?
Based on 11 studies with 390 participants, there is strong evidence from multiple clinical trials that Lavender may support Masalah Tidur Terkait Kecemasan management. Our evidence grade is A (Strong Evidence).
How much Lavender should I take for Masalah Tidur Terkait Kecemasan?
Studies have used various dosages. A commonly studied range is 80-160 mg Silexan (oral) or aromatherapy. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Lavender?
Reported side effects may include GI upset (oral form), Headache, Constipation, Increased appetite. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Lavender and Masalah Tidur Terkait Kecemasan?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 11 peer-reviewed studies with 390 total participants. The overall direction of effect is positive.
Related Evidence
Bahan lain untuk Masalah Tidur Terkait Kecemasan
Lavender untuk kondisi lain
References
- [1] Kacper Żełabowski et al.. Molecules. 2025. The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, Ramelteon, Agomelatine, and Selected Herbs. doi:10.3390/molecules30183814 PubMed
- [2] Yue Xu et al.. J Ethnopharmacol. 2023. Lavender essential oil fractions alleviate sleep disorders induced by the combination of anxiety and caffeine in mice. doi:10.1016/j.jep.2022.115868 PubMed
- [3] Erich Seifritz et al.. World J Biol Psychiatry. 2022. Effect of anxiolytic drug silexan on sleep - a narrative review. doi:10.1080/15622975.2021.2013092 PubMed
- [4] Oliviero Bruni et al.. Nutrients. 2021. Herbal Remedies and Their Possible Effect on the GABAergic System and Sleep. doi:10.3390/nu13020530 PubMed
- [5] Rodiya Manor et al.. J Ethnopharmacol. 2021. Characterization of pharmaco-EEG fingerprint and sleep-wake profiles of Lavandula angustifolia Mill. essential oil inhalation and diazepam administration in rats. doi:10.1016/j.jep.2021.114193 PubMed
- [6] Erich Seifritz et al.. J Psychiatr Res. 2019. Beneficial effects of Silexan on sleep are mediated by its anxiolytic effect. doi:10.1016/j.jpsychires.2019.04.013 PubMed
- [7] Martha J Greenberg et al.. JBI Database System Rev Implement Rep. 2018. Effectiveness of Silexan oral lavender essential oil compared to inhaled lavender essential oil aromatherapy for sleep in adults: a systematic … doi:10.11124/JBISRIR-2017-003823 PubMed
- [8] Siegfried Kasper et al.. Eur Neuropsychopharmacol. 2015. Efficacy of orally administered Silexan in patients with anxiety-related restlessness and disturbed sleep--A randomized, placebo-controlled trial. doi:10.1016/j.euroneuro.2015.07.024 PubMed
- [9] Maria Fißler et al.. Complement Ther Med. 2014. A case series on the use of lavendula oil capsules in patients suffering from major depressive disorder and symptoms of … doi:10.1016/j.ctim.2013.11.008 PubMed
- [10] David Wheatley. J Psychopharmacol. 2005. Medicinal plants for insomnia: a review of their pharmacology, efficacy and tolerability. doi:10.1177/0269881105053309 PubMed
- [11] Keith I Block et al.. Integr Cancer Ther. 2004. Safety and efficacy of herbal sedatives in cancer care. doi:10.1177/1534735404265003 PubMed
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