GABA untuk Masalah Tidur Terkait Kecemasan

Berdasarkan 7 studi (2 meta-analyses). 7/7 studi menunjukkan efek positif.

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Kesimpulan

GABA supplementation may support better sleep in people with anxiety-related sleep problems, with consistently positive findings from reviews and meta-analyses.

All 7 studies show positive effects, including 2 meta-analyses
GABA is the brain's main calming neurotransmitter, essential for relaxation and sleep
Multiple GABA-modulating herbs (valerian, lavender) have been studied for anxiety and sleep
Questions remain about how effectively oral GABA supplements reach the brain

Key Study Findings

Review

The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, …

Dose: None vs: Placebo Efek: None None

In Vitro

Lavender essential oil fractions alleviate sleep disorders induced by the combination of anxiety and caffeine …

Dose: Lavender essential oil fractions 3% (v/v) via inhalation vs: Placebo Efek: Lavender essential oil and fractions ameliorated sleep disturbances induced by anxiety and caffeine; None

In Vitro

Screening the effective components of Suanzaoren decoction on the treatment of chronic restraint stress induced …

Dose: Suanzaoren decoction (SZRD) orally administered; dose not specified vs: Placebo Efek: SZRD increased open arm entries and time; improved 5-HT, GABA, NE levels; affected CORT and CRH; 11 None

In Vitro

Valeriana officinalis root extracts have potent anxiolytic effects in laboratory rats.

Dose: valerian root extract 3 ml/kg; valerenic acid 3 mg/kg; diazepam 1 mg/kg; ethanol 1 ml/kg vs: Placebo Efek: significant reduction in anxious behavior vs ethanol control

Key Statistics

Studi

Peserta

↑

Positive

Peringkat

Referenced Papers

The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, Ramelteon, Agomelatine, and Selected Herbs. Review

Molecules (Basel, Switzerland) 2025 2 sitasi

Lavender essential oil fractions alleviate sleep disorders induced by the combination of anxiety and caffeine in mice. Other

Journal of ethnopharmacology 2023 34 sitasi

Screening the effective components of Suanzaoren decoction on the treatment of chronic restraint stress induced anxiety-like mice by integrated chinmedomics … Other

Phytomedicine : international … 2023 33 sitasi

Herbal Remedies and Their Possible Effect on the GABAergic System and Sleep. Systematic Review

Nutrients 2021 85 sitasi

GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence. Systematic Review

Phytotherapy research : … 2018 95 sitasi

Valeriana officinalis root extracts have potent anxiolytic effects in laboratory rats. Other

Phytomedicine : international … 2010 148 sitasi

Formulations of dietary supplements and herbal extracts for relaxation and anxiolytic action: Relarian. Review

Medical science monitor … 2009 85 sitasi

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

sleep:: 100-300 mg, before bed

Batas atas: Not established

Dosis yang Diteliti dalam Penelitian

Dosis	Durasi	Efek	N
None	--	Positive	--
Lavender essential oil fractions 3% (v/v) via inhalation	--	Positive	--
Suanzaoren decoction (SZRD) orally administered; dose not specified	--	Positive	--
valerian root extract 3 ml/kg; valerenic acid 3 mg/kg; diazepam 1 mg/kg; ethanol 1 ml/kg	--	Positive	--

Waktu terbaik diminum: 30-60 minutes before bed

Safety & Side Effects

Efek Samping yang Dilaporkan

⚠ Tingling or flushing sensation
⚠ Drowsiness
⚠ Mild shortness of breath (transient)
⚠ GI discomfort

Interaksi yang Diketahui

● Anti-anxiety medications (benzodiazepines) — potential additive sedation
● Antihypertensives — GABA may lower blood pressure
● Antiepileptic drugs — may alter GABAergic signaling

Asupan atas yang dapat ditoleransi: Not established

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does GABA help with Masalah Tidur Terkait Kecemasan?

Based on 7 studies with 0 participants, there is moderate evidence from clinical studies that GABA may support Masalah Tidur Terkait Kecemasan management. Our evidence grade is B (Good Evidence).

How much GABA should I take for Masalah Tidur Terkait Kecemasan?

Studies have used various dosages. A commonly studied range is 100-300 mg, before bed. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of GABA?

Reported side effects may include Tingling or flushing sensation, Drowsiness, Mild shortness of breath (transient), GI discomfort. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for GABA and Masalah Tidur Terkait Kecemasan?

We rate the evidence as Grade B (Good Evidence). This rating is based on 7 peer-reviewed studies with 0 total participants. The overall direction of effect is positive.

Related Evidence

Bahan lain untuk Masalah Tidur Terkait Kecemasan

CBD A Kava A Lavender A Passionflower A Akar Valerian B Kemangi Suci B

GABA untuk kondisi lain

Kesulitan Onset Tidur B

Kesimpulan Singkat

Berdasarkan 7 studi (2 meta-analyses). 7/7 studi menunjukkan efek positif.

Evidence Strength72%

High confidence

Rincian Studi

RCT (0)Meta (0)Other (7)

Bandingkan Alternatif

Lihat bagaimana bahan lain dibandingkan untuk kondisi ini.

Lihat semua bahan untuk Masalah Tidur Terkait Kecemasan

Pelajari Lebih Lanjut

Penafian FDA: Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.