CBD untuk Masalah Tidur Terkait Kecemasan
A Bukti Beberapa uji klinis besar secara konsisten menunjukkan manfaat yang signifikan.Berdasarkan 35 studi (5 meta-analyses, 11 RCTs) dengan 17,358 peserta secara total. 19/35 studi menunjukkan efek positif.
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A
Kesimpulan
CBD may support better sleep in people whose rest is disrupted by anxiety, though results are mixed and the best dose and formulation are still being studied.
- 35 studies with 17,358 participants — the largest evidence base among anxiety-sleep supplements
- Roughly 54% of studies show positive effects, with others showing mixed results
- May work through 5-HT1A serotonin receptors to reduce anxiety and promote sleep
- Dosing varies widely across studies (25 mg to 300+ mg), making direct comparisons difficult
Key Study Findings
Other
Development of a novel Δ9-THC-specific color test reagent.
Dose: None
vs: None
Outcome: None
Efek: None
None
Populasi: Lab study: novel THC-specific color test reagent
Observational Study
Trends in burden and mortality of congenital birth defects in G20 countries (1990-2021) and predictions …
Dose: None
vs: None
Outcome: DALYs and mortality rates of congenital birth defects
Efek: DALYs decreased 59.77%, deaths decreased 63.81%
None
Populasi: G20 countries population, 1990-2021
Other
Policy reform and the international future of Moroccan Cannabis production.
Dose: None
vs: None
Outcome: None
Efek: None
None
Populasi: None
Observational Study
n=126
The use of complementary and alternative medicine among cancer patients in Hawaii.
Dose: None
vs: None
Outcome: CAM therapy use patterns among cancer patients
Efek: 57.1% used at least one CAM therapy
None
Populasi: Cancer patients in Hawaii
Systematic Review
The Effect of Cannabidiol on Performance and Post-Load Recovery among Healthy and Physically Active Individuals: …
Dose: None
vs: None
Outcome: None
Efek: None
None
Populasi: Healthy adults
Other
5 weeks
Dietary Cannabidiol Activates PKA/AMPK Signaling and Attenuates Chronic Inflammation and Leaky Gut in DSS-Induced Colitis …
Dose: 200 mg
vs: None
Outcome: Colitis severity
Efek: None
None
Populasi: Mouse model
Key Statistics
35
Studi
1794
Peserta
↔
Mixed
A
Peringkat
Referenced Papers
BMC pregnancy and …
2025
6 sitasi
Forensic toxicology
2025
1 sitasi
The International journal …
2025
1 sitasi
BMC complementary medicine …
2025
Medical cannabis and …
2024
26 sitasi
Molecular nutrition & …
2024
15 sitasi
Neurochemical research
2024
14 sitasi
Cannabis and cannabinoid …
2024
10 sitasi
A systematic review and meta-analysis of functional vitamin B12 status among adult vegans.
Meta-Analysis
Nutrition bulletin
2024
9 sitasi
International journal of …
2024
7 sitasi
Effects of Dietary Supplementation in Patients with Restless Legs Syndrome: A Systematic Review.
Systematic Review
Nutrients
2024
5 sitasi
The Effect of Cannabidiol on Performance and Post-Load Recovery among Healthy and Physically Active Individuals: A Systematic Review.
Systematic Review
Nutrients
2024
4 sitasi
Pharmaceutics
2024
4 sitasi
Journal of sleep …
2023
40 sitasi
Mechanisms of ageing …
2023
8 sitasi
A Systematic Review of the Benefit of B-Vitamins as a Complementary Treatment in Cancer Patients.
Systematic Review
Nutrition and cancer
2023
5 sitasi
Food & nutrition …
2023
5 sitasi
Journal of personalized …
2023
3 sitasi
American family physician
2023
The Journal of …
2022
35 sitasi
Proceedings. IEEE International …
2021
29 sitasi
Prevalence of Cannabidiol Use in Patients With Spine Complaints: Results of an Anonymous Survey.
Other
International journal of …
2021
14 sitasi
Veterinary medicine (Auckland, …
2020
45 sitasi
Cureus
2020
23 sitasi
Parkinsonian Syndrome with Frontal Lobe Involvement and Anti-Glycine Receptor Antibodies.
Case Report
Brain sciences
2020
12 sitasi
Public health nutrition
2018
35 sitasi
Nutricion hospitalaria
2015
161 sitasi
Current osteoporosis reports
2013
43 sitasi
Adolescent medicine: state …
2013
3 sitasi
Ontario health technology …
2013
Systematic review: Progression of beryllium sensitization to chronic beryllium disease.
Systematic Review
Occupational medicine (Oxford, …
2012
33 sitasi
Vitamin B6, B12, and folic acid supplementation and cognitive function: a systematic review of randomized trials.
Systematic Review
Archives of internal …
2007
222 sitasi
A systematic review of the evidence supporting the use of priority dispatch of emergency ambulances.
Systematic Review
Prehospital emergency care
2002
33 sitasi
The Urologic clinics …
2002
20 sitasi
European journal of …
1989
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosis yang Umum Digunakan
- sleep:
- 25-150 mg, 1 hour before bed
Batas atas: Not established; FDA max studied ~20 mg/kg/day
Dosis yang Diteliti dalam Penelitian
| Dosis | Durasi | Efek | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Mixed | 126 |
| None | -- | Positive | -- |
| 200 mg | 5 weeks | Positive | -- |
| cannabidiol (CBD) at various doses administered to mice | -- | Positive | -- |
| None | -- | Positive | -- |
Waktu terbaik diminum: 1 hour before bed
Safety & Side Effects
Efek Samping yang Dilaporkan
- ⚠ Fatigue
- ⚠ Diarrhea
- ⚠ Changes in appetite
- ⚠ Dry mouth
- ⚠ Liver enzyme elevation at high doses
Interaksi yang Diketahui
- ● CYP3A4/CYP2C19 substrates — CBD inhibits these liver enzymes
- ● Blood thinners (warfarin) — CBD may increase warfarin levels
- ● Clobazam — CBD significantly increases clobazam levels
- ● Sedatives — additive drowsiness
Asupan atas yang dapat ditoleransi: Not established; FDA max studied ~20 mg/kg/day
Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.
Frequently Asked Questions
Does CBD help with Masalah Tidur Terkait Kecemasan?
Based on 35 studies with 1,794 participants, there is strong evidence from multiple clinical trials that CBD may support Masalah Tidur Terkait Kecemasan management. Our evidence grade is A (Strong Evidence).
How much CBD should I take for Masalah Tidur Terkait Kecemasan?
Studies have used various dosages. A commonly studied range is 25-150 mg, 1 hour before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of CBD?
Reported side effects may include Fatigue, Diarrhea, Changes in appetite, Dry mouth. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for CBD and Masalah Tidur Terkait Kecemasan?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 35 peer-reviewed studies with 1,794 total participants. The overall direction of effect is mixed.
Related Evidence
Bahan lain untuk Masalah Tidur Terkait Kecemasan
CBD untuk kondisi lain
References
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