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Akar Valerian untuk Kesulitan Onset Tidur

B

Berdasarkan 5 studi (1 meta-analysis, 1 RCT) dengan 15 peserta secara total. 3/5 studi menunjukkan efek positif.

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            B

        

        

            
Kesimpulan

            
            
Valerian root may help with falling asleep, but the evidence specific to sleep onset difficulty is limited by very small studies.

            
            
            
    
                
                
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                    Only 5 studies with 15 total participants — very small evidence base for this specific use
                
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                    60% of studies show positive effects on falling asleep
                
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                    Includes 1 meta-analysis and 1 RCT, but sample sizes are very small
                
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  • 
                    
                    Stronger evidence exists for valerian's general insomnia benefits
                
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Key Study Findings





    

        
        

            

                
                    Review
                
                
                
                
            

            
                The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, …
            
            

                
                Dose: None
                
                
                vs: Placebo
                
                
                
                Efek: None
                
                
                None
                
            

            
        

        
        

            

                
                    Randomized Controlled Trial
                
                
                n=15
                
                
                2 weeks
                
                
                Double-blind
                
            

            
                Effects of a tart cherry juice beverage on the sleep of older adults with insomnia: …
            
            

                
                Dose: Tart cherry juice blend (CherryPharm) twice daily for 2 weeks
                
                
                vs: Placebo
                
                
                
                Efek: Significant reduction in wake after sleep onset vs placebo; effect sizes moderate to negligible
                
                
            

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
5

        
Studi

    

    

        
15

        
Peserta

    

    

        
            
            ↑
            
        
        
Positive

    

    

        B

        
Peringkat

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, Ramelteon, Agomelatine, and Selected Herbs.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Molecules (Basel, Switzerland)
                        2025
                        
                        2 sitasi
                        
                    

                

                
                

                    

                        
                            Herbal Remedies and Their Possible Effect on the GABAergic System and Sleep.
                        
                        
                            
                                Systematic Review
                            
                            
                            
                        
                    

                    

                        Nutrients
                        2021
                        
                        85 sitasi
                        
                    

                

                
                

                    

                        
                            Insomnia in Elderly Patients: Recommendations for Pharmacological Management.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Drugs & aging
                        2018
                        
                        131 sitasi
                        
                    

                

                
                

                    

                        
                            Clinical Practice Guideline for the Pharmacologic Treatment of Chronic Insomnia in Adults: An American Academy of Sleep Medicine Clinical Practice …
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Journal of clinical …
                        2017
                        
                        1097 sitasi
                        
                    

                

                
                

                    

                        
                            Effects of a tart cherry juice beverage on the sleep of older adults with insomnia: a pilot study.
                        
                        
                            
                                RCT
                            
                            
                            
                        
                    

                    

                        Journal of medicinal …
                        2010
                        
                        157 sitasi
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Dosis yang Umum Digunakan

                

                    
                    

                        
sleep:

                        
300-600 mg standardized extract, 30 min before bed

                    

                    
                

                
                

                    Batas atas: Not established
                

                
            

            

            
            

                
Dosis yang Diteliti dalam Penelitian

                

                    

                        
                            

                                Dosis
                                Durasi
                                Efek
                                N
                            

                        
                        
                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                            

                                Tart cherry juice blend (CherryPharm) twice daily for 2 weeks
                                2 weeks
                                
                                    
                                    Positive
                                    
                                
                                15
                            

                            
                        
                    

                

            

            

            
            

                Waktu terbaik diminum: 30-60 minutes before bed; may require 2-4 weeks for full effect
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Efek Samping yang Dilaporkan

                    
    
                        
                        
  • 
                            ⚠
                            Headache
                        
    • 
                        
                        
  • 
                            ⚠
                            Dizziness
                        
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  • 
                            ⚠
                            GI upset
                        
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  • 
                            ⚠
                            Morning grogginess
                        
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  • 
                            ⚠
                            Vivid dreams
                        
    • 
                        
                    

                

                

                
                

                    
Interaksi yang Diketahui

                    
    
                        
                        
  • 
                            ●
                            Sedatives and alcohol — additive CNS depression
                        
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  • 
                            ●
                            CYP3A4-metabolized drugs — valerian may inhibit this enzyme
                        
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  • 
                            ●
                            Benzodiazepines — potential additive GABA effects
                        
    • 
                        
                    

                

                

                
                

                    

                        Asupan atas yang dapat ditoleransi: Not established
                    

                

                
            

            

                Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Akar Valerian help with Kesulitan Onset Tidur?
            
        
        

            Based on 5 studies with 15 participants, there is moderate evidence from clinical studies that Akar Valerian may support Kesulitan Onset Tidur management. Our evidence grade is B (Good Evidence).
        

    

    
    

        
            How much Akar Valerian should I take for Kesulitan Onset Tidur?
            
        
        

            Studies have used various dosages. A commonly studied range is 300-600 mg standardized extract, 30 min before bed. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Akar Valerian?
            
        
        

            Reported side effects may include Headache, Dizziness, GI upset, Morning grogginess. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Akar Valerian and Kesulitan Onset Tidur?
            
        
        

            We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 15 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
                

                    
Akar Valerian untuk kondisi lain

                    

                        
                        
                            Insomnia
                            A

                        
                        
                        
                            Masalah Tidur Terkait Kecemasan
                            B

                        
                        
                    

                

                
            

        

        

    


    
    












    

        Penafian FDA:
        Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.