Radice di valeriana per Difficoltà di addormentamento

B Evidenze Almeno un trial randomizzato lo supporta, con risultati per lo più coerenti.

Basato su 5 studi (1 meta-analysis, 1 RCT) con 15 partecipanti totali. 3/5 studi mostrano effetti positivi.

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In sintesi

Valerian root may help with falling asleep, but the evidence specific to sleep onset difficulty is limited by very small studies.

Only 5 studies with 15 total participants — very small evidence base for this specific use
60% of studies show positive effects on falling asleep
Includes 1 meta-analysis and 1 RCT, but sample sizes are very small
Stronger evidence exists for valerian's general insomnia benefits

Key Study Findings

Review

The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, …

Dose: None vs: Placebo Effetto: None None

Randomized Controlled Trial n=15 2 weeks Double-blind

Effects of a tart cherry juice beverage on the sleep of older adults with insomnia: …

Dose: Tart cherry juice blend (CherryPharm) twice daily for 2 weeks vs: Placebo Effetto: Significant reduction in wake after sleep onset vs placebo; effect sizes moderate to negligible

Key Statistics

Studi

Partecipanti

↑

Positive

Grado

Referenced Papers

The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, Ramelteon, Agomelatine, and Selected Herbs. Review

Molecules (Basel, Switzerland) 2025 2 citazioni

Herbal Remedies and Their Possible Effect on the GABAergic System and Sleep. Systematic Review

Nutrients 2021 85 citazioni

Insomnia in Elderly Patients: Recommendations for Pharmacological Management. Review

Drugs & aging 2018 131 citazioni

Clinical Practice Guideline for the Pharmacologic Treatment of Chronic Insomnia in Adults: An American Academy of Sleep Medicine Clinical Practice … Other

Journal of clinical … 2017 1097 citazioni

Effects of a tart cherry juice beverage on the sleep of older adults with insomnia: a pilot study. RCT

Journal of medicinal … 2010 157 citazioni

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosaggi di uso comune

sleep:: 300-600 mg standardized extract, 30 min before bed

Limite massimo: Not established

Dosaggi studiati nella ricerca

Dosaggio	Durata	Effetto	N
None	--	Positive	--
Tart cherry juice blend (CherryPharm) twice daily for 2 weeks	2 weeks	Positive	15

Momento migliore per l'assunzione: 30-60 minutes before bed; may require 2-4 weeks for full effect

Safety & Side Effects

Effetti collaterali segnalati

⚠ Headache
⚠ Dizziness
⚠ GI upset
⚠ Morning grogginess
⚠ Vivid dreams

Interazioni note

● Sedatives and alcohol — additive CNS depression
● CYP3A4-metabolized drugs — valerian may inhibit this enzyme
● Benzodiazepines — potential additive GABA effects

Livello di assunzione massimo tollerabile: Not established

Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.

Frequently Asked Questions

Does Radice di valeriana help with Difficoltà di addormentamento?

Based on 5 studies with 15 participants, there is moderate evidence from clinical studies that Radice di valeriana may support Difficoltà di addormentamento management. Our evidence grade is B (Good Evidence).

How much Radice di valeriana should I take for Difficoltà di addormentamento?

Studies have used various dosages. A commonly studied range is 300-600 mg standardized extract, 30 min before bed. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Radice di valeriana?

Reported side effects may include Headache, Dizziness, GI upset, Morning grogginess. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Radice di valeriana and Difficoltà di addormentamento?

We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 15 total participants. The overall direction of effect is positive.

Altri ingredienti per Difficoltà di addormentamento

Vitamina B6 A Magnesio glicinato A Zinco A Melatonin A Hops A L-Theanine A

Radice di valeriana per altre condizioni

Insonnia A Problemi di sonno legati all'ansia B

Verdetto rapido

Basato su 5 studi (1 meta-analysis, 1 RCT) con 15 partecipanti totali. 3/5 studi mostrano effetti positivi.

Evidence Strength72%

High confidence

Analisi degli studi

RCT (1)Meta (0)Other (4)

Confronta le alternative

Scoprite come si confrontano altri ingredienti per questa condizione.

Visualizza tutti gli ingredienti per Difficoltà di addormentamento

Approfondimenti

References

[1] Kacper Żełabowski et al.. Molecules. 2025. The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, Ramelteon, Agomelatine, and Selected Herbs. doi:10.3390/molecules30183814 PubMed
[2] Oliviero Bruni et al.. Nutrients. 2021. Herbal Remedies and Their Possible Effect on the GABAergic System and Sleep. doi:10.3390/nu13020530 PubMed
[3] Vivien C Abad et al.. Drugs Aging. 2018. Insomnia in Elderly Patients: Recommendations for Pharmacological Management. doi:10.1007/s40266-018-0569-8 PubMed
[4] Michael J Sateia et al.. J Clin Sleep Med. 2017. Clinical Practice Guideline for the Pharmacologic Treatment of Chronic Insomnia in Adults: An American Academy of Sleep Medicine Clinical Practice … doi:10.5664/jcsm.6470 PubMed
[5] Wilfred R Pigeon et al.. J Med Food. 2010. Effects of a tart cherry juice beverage on the sleep of older adults with insomnia: a pilot study. doi:10.1089/jmf.2009.0096 PubMed

Avvertenza FDA: Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.