Hops per Difficoltà di addormentamento

Based on 8 studies (1 meta-analysis, 3 RCTs) with 2,688 total participants. 6/8 studies show positive effects.

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In sintesi

Based on 8 studies (1 meta-analysis, 3 RCTs) with 2,688 total participants. 6/8 studies show positive effects.

Key Study Findings

Randomized Controlled Trial n=40 3 weeks Double-blind

Effects of a Valerian-Hops Extract Combination (Ze 91019) on Sleep Duration and Daytime Cognitive and …

Dose: None vs: Placebo Outcome: Sleep duration (Fitbit tracker) Effetto: Mean +21.7 min/night; shortest night +48.7 min 0.019

Popolazione: Adults with occasional sleep problems

Observational Study n=2464

Young adults' knowledge, perceptions and use of cannabidiol products: a mixed-methods study.

Dose: None vs: None Outcome: CBD knowledge, perceptions, and use Effetto: None None

Popolazione: US young adults, mean age 24.67y

narrative review

Use of Plant-Derived Natural Products in Sleep Disturbances.

Dose: varies by product and study vs: Placebo Effetto: None None

In Vitro

Effect of Valerian/Hop Mixture on Sleep-Related Behaviors in Drosophila melanogaster.

Dose: valerian/hops mixture (20 mg/mL valerian) vs: control diet Outcome: sleep duration and GABA receptor expression Effetto: ~20% longer sleeping time None

Popolazione: Drosophila melanogaster (fruit flies)

Systematic Review

Over-the-Counter Agents for the Treatment of Occasional Disturbed Sleep or Transient Insomnia: A Systematic Review …

Dose: None vs: placebo Outcome: None Effetto: None None

Popolazione: insomnia patients

Randomized Controlled Trial Double-blind

Treating primary insomnia - the efficacy of valerian and hops.

Dose: None vs: placebo Outcome: sleep quality Effetto: None None

Popolazione: None

Key Statistics

Studi

2688

Partecipanti

↑

Positive

Grado

Referenced Papers

Effects of a Valerian-Hops Extract Combination (Ze 91019) on Sleep Duration and Daytime Cognitive and Psychological Parameters in Occasional Insomnia: … RCT

Brain and behavior 2025 1 citazioni

Young adults' knowledge, perceptions and use of cannabidiol products: a mixed-methods study. Other

Health education research 2022 14 citazioni

Use of Plant-Derived Natural Products in Sleep Disturbances. Review

Advances in experimental … 2021 7 citazioni

Effect of Valerian/Hop Mixture on Sleep-Related Behaviors in Drosophila melanogaster. Other

Biological & pharmaceutical … 2017 20 citazioni

Over-the-Counter Agents for the Treatment of Occasional Disturbed Sleep or Transient Insomnia: A Systematic Review of Efficacy and Safety. Other

The primary care … 2015 51 citazioni

Treating primary insomnia - the efficacy of valerian and hops. Review

Australian family physician 2010 58 citazioni

Treating the health, quality of life, and functional impairments in insomnia. Review

Journal of clinical … 2007

Valerian-hops combination and diphenhydramine for treating insomnia: a randomized placebo-controlled clinical trial. RCT

Sleep 2005 187 citazioni

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosaggi di uso comune

sleep:: 300-500 mg extract, 30-60 min before bed; often combined with valerian

Limite massimo: Not formally established

Dosaggi studiati nella ricerca

Dosaggio	Durata	Effetto	N
None	3 weeks	Positive	40
None	--	Neutral	2464
varies by product and study	--	Mixed	--
valerian/hops mixture (20 mg/mL valerian)	--	Positive	--
None	--	Positive	--
None	--	Positive	--
None	--	Positive	--
Valerian 187mg + hops 41.9mg extract, 2 tablets nightly	4 weeks	Positive	184

Momento migliore per l'assunzione: 30-60 minutes before bed; commonly used with valerian root for synergistic effects

Safety & Side Effects

Effetti collaterali segnalati

⚠ Drowsiness (intended effect)
⚠ Mild estrogenic effects (theoretical from prenylated flavonoids)
⚠ Allergic reactions in hop-sensitive individuals

Interazioni note

● Sedatives and CNS depressants — additive effects
● Estrogen-sensitive conditions — hops contain phytoestrogens
● CYP450 substrates — mild enzyme inhibition reported

Livello di assunzione massimo tollerabile: Not formally established

Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.

Frequently Asked Questions

Does Hops help with Difficoltà di addormentamento?

Based on 8 studies with 2,688 participants, there is strong evidence from multiple clinical trials that Hops may support Difficoltà di addormentamento management. Our evidence grade is A (Strong Evidence).

How much Hops should I take for Difficoltà di addormentamento?

Studies have used various dosages. A commonly studied range is 300-500 mg extract, 30-60 min before bed; often combined with valerian. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Hops?

Reported side effects may include Drowsiness (intended effect), Mild estrogenic effects (theoretical from prenylated flavonoids), Allergic reactions in hop-sensitive individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Hops and Difficoltà di addormentamento?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 8 peer-reviewed studies with 2,688 total participants. The overall direction of effect is positive.

Related Evidence

Altri ingredienti per Difficoltà di addormentamento

Vitamina B6 A Magnesio glicinato A Zinco A Melatonin A L-Theanine A Apigenin B

Hops per altre condizioni

Insonnia A Menopause-Related Sleep Disturbance A

Verdetto rapido

Based on 8 studies (1 meta-analysis, 3 RCTs) with 2,688 total participants. 6/8 studies show positive effects.

Evidence Strength92%

High confidence

Analisi degli studi

RCT (2)Meta (0)Other (6)

Confronta le alternative

Scoprite come si confrontano altri ingredienti per questa condizione.

Visualizza tutti gli ingredienti per Difficoltà di addormentamento

Approfondimenti

Avvertenza FDA: Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.