홉 관련 수면 개시 장애

홉(Humulus lupulus)에는 홉산에서 분해되는 진정 특성을 가진 화합물 2-methyl-3-buten-2-ol이 포함되어 있습니다. 대부분의 임상 근거는 홉을 길초근(valerian)과 병용한 것이므로 홉의 독립적 기여를 분리하기 어렵습니다. 소수의 소규모 단일 요법 시험에서 수면 시작 지연 시간의 완만한 개선을 시사합니다.

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결론

Key Study Findings

Randomized Controlled Trial n=40 3 weeks Double-blind

Effects of a Valerian-Hops Extract Combination (Ze 91019) on Sleep Duration and Daytime Cognitive and …

Dose: None vs: Placebo Outcome: Sleep duration (Fitbit tracker) 효과: Mean +21.7 min/night; shortest night +48.7 min 0.019

대상 집단: Adults with occasional sleep problems

Observational Study n=2464

Young adults' knowledge, perceptions and use of cannabidiol products: a mixed-methods study.

Dose: None vs: None Outcome: CBD knowledge, perceptions, and use 효과: None None

대상 집단: US young adults, mean age 24.67y

narrative review

Use of Plant-Derived Natural Products in Sleep Disturbances.

Dose: varies by product and study vs: Placebo 효과: None None

In Vitro

Effect of Valerian/Hop Mixture on Sleep-Related Behaviors in Drosophila melanogaster.

Dose: valerian/hops mixture (20 mg/mL valerian) vs: control diet Outcome: sleep duration and GABA receptor expression 효과: ~20% longer sleeping time None

대상 집단: Drosophila melanogaster (fruit flies)

Systematic Review

Over-the-Counter Agents for the Treatment of Occasional Disturbed Sleep or Transient Insomnia: A Systematic Review …

Dose: None vs: placebo Outcome: None 효과: None None

대상 집단: insomnia patients

Randomized Controlled Trial Double-blind

Treating primary insomnia - the efficacy of valerian and hops.

Dose: None vs: placebo Outcome: sleep quality 효과: None None

대상 집단: None

Key Statistics

연구

2688

참여자

↑

Positive

등급

Referenced Papers

Effects of a Valerian-Hops Extract Combination (Ze 91019) on Sleep Duration and Daytime Cognitive and Psychological Parameters in Occasional Insomnia: … RCT

Brain and behavior 2025 1 인용

Young adults' knowledge, perceptions and use of cannabidiol products: a mixed-methods study. Other

Health education research 2022 14 인용

Use of Plant-Derived Natural Products in Sleep Disturbances. Review

Advances in experimental … 2021 7 인용

Effect of Valerian/Hop Mixture on Sleep-Related Behaviors in Drosophila melanogaster. Other

Biological & pharmaceutical … 2017 20 인용

Over-the-Counter Agents for the Treatment of Occasional Disturbed Sleep or Transient Insomnia: A Systematic Review of Efficacy and Safety. Other

The primary care … 2015 51 인용

Treating primary insomnia - the efficacy of valerian and hops. Review

Australian family physician 2010 58 인용

Treating the health, quality of life, and functional impairments in insomnia. Review

Journal of clinical … 2007

Valerian-hops combination and diphenhydramine for treating insomnia: a randomized placebo-controlled clinical trial. RCT

Sleep 2005 187 인용

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

일반적으로 사용되는 용량

sleep:: 300-500 mg extract, 30-60 min before bed; often combined with valerian

상한량: Not formally established

연구에서 사용된 용량

용량	기간	효과	N
None	3 weeks	Positive	40
None	--	Neutral	2464
varies by product and study	--	Mixed	--
valerian/hops mixture (20 mg/mL valerian)	--	Positive	--
None	--	Positive	--
None	--	Positive	--
None	--	Positive	--
Valerian 187mg + hops 41.9mg extract, 2 tablets nightly	4 weeks	Positive	184

권장 복용 시간: 30-60 minutes before bed; commonly used with valerian root for synergistic effects

Safety & Side Effects

보고된 부작용

⚠ Drowsiness (intended effect)
⚠ Mild estrogenic effects (theoretical from prenylated flavonoids)
⚠ Allergic reactions in hop-sensitive individuals

알려진 상호작용

● Sedatives and CNS depressants — additive effects
● Estrogen-sensitive conditions — hops contain phytoestrogens
● CYP450 substrates — mild enzyme inhibition reported

일일 최대 섭취 허용량: Not formally established

건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.

Frequently Asked Questions

Does 홉 help with 수면 개시 장애?

Based on 8 studies with 2,688 participants, there is strong evidence from multiple clinical trials that 홉 may support 수면 개시 장애 management. Our evidence grade is A (Strong Evidence).

How much 홉 should I take for 수면 개시 장애?

Studies have used various dosages. A commonly studied range is 300-500 mg extract, 30-60 min before bed; often combined with valerian. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of 홉?

Reported side effects may include Drowsiness (intended effect), Mild estrogenic effects (theoretical from prenylated flavonoids), Allergic reactions in hop-sensitive individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for 홉 and 수면 개시 장애?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 8 peer-reviewed studies with 2,688 total participants. The overall direction of effect is positive.

Related Evidence

홉 다른 건강 상태에 대한 근거

불면증 A 폐경 관련 수면 장애 A

한눈에 보기

홉(Humulus lupulus)에는 홉산에서 분해되는 진정 특성을 가진 화합물 2-methyl-3-buten-2-ol이 포함되어 있습니다. 대부분의 임상 근거는 홉을 길초근(valerian)과 병용한 것이므로 홉의 독립적 기여를 분리하기 어렵습니다. 소수의 소규모 단일 요법 시험에서 수면 시작 …

Evidence Strength92%

High confidence

연구 분석

RCT (2)Meta (0)Other (6)

대안 비교

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모든 성분 보기: 수면 개시 장애

자세히 알아보기

FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.