バレリアンルート：入眠困難

B エビデンス少なくとも1件のランダム化試験がこれを支持しており、おおむね一貫した結果が得られています。

合計15名の参加者を対象とした5件の研究（メタアナリシス1件、RCT 1件を含む）に基づく。5件中3件の研究で肯定的な効果が示されている。

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結論

Valerian root may help with falling asleep, but the evidence specific to sleep onset difficulty is limited by very small studies.

Only 5 studies with 15 total participants — very small evidence base for this specific use
60% of studies show positive effects on falling asleep
Includes 1 meta-analysis and 1 RCT, but sample sizes are very small
Stronger evidence exists for valerian's general insomnia benefits

Key Study Findings

Review

The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, …

Dose: None vs: Placebo 効果: None None

Randomized Controlled Trial n=15 2 weeks Double-blind

Effects of a tart cherry juice beverage on the sleep of older adults with insomnia: …

Dose: Tart cherry juice blend (CherryPharm) twice daily for 2 weeks vs: Placebo 効果: Significant reduction in wake after sleep onset vs placebo; effect sizes moderate to negligible

Key Statistics

研究数

参加者数

↑

Positive

グレード

Referenced Papers

The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, Ramelteon, Agomelatine, and Selected Herbs. Review

Molecules (Basel, Switzerland) 2025 2 件の引用

Herbal Remedies and Their Possible Effect on the GABAergic System and Sleep. Systematic Review

Nutrients 2021 85 件の引用

Insomnia in Elderly Patients: Recommendations for Pharmacological Management. Review

Drugs & aging 2018 131 件の引用

Clinical Practice Guideline for the Pharmacologic Treatment of Chronic Insomnia in Adults: An American Academy of Sleep Medicine Clinical Practice … Other

Journal of clinical … 2017 1097 件の引用

Effects of a tart cherry juice beverage on the sleep of older adults with insomnia: a pilot study. RCT

Journal of medicinal … 2010 157 件の引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

一般的な使用量

sleep:: 300-600 mg standardized extract, 30 min before bed

上限量： Not established

研究で検討された用量

用量	期間	効果	N
None	--	Positive	--
Tart cherry juice blend (CherryPharm) twice daily for 2 weeks	2 weeks	Positive	15

推奨摂取タイミング： 30-60 minutes before bed; may require 2-4 weeks for full effect

Safety & Side Effects

報告されている副作用

⚠ Headache
⚠ Dizziness
⚠ GI upset
⚠ Morning grogginess
⚠ Vivid dreams

既知の相互作用

● Sedatives and alcohol — additive CNS depression
● CYP3A4-metabolized drugs — valerian may inhibit this enzyme
● Benzodiazepines — potential additive GABA effects

耐容上限摂取量： Not established

サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

Frequently Asked Questions

Does バレリアンルート help with 入眠困難?

Based on 5 studies with 15 participants, there is moderate evidence from clinical studies that バレリアンルート may support 入眠困難 management. Our evidence grade is B (Good Evidence).

How much バレリアンルート should I take for 入眠困難?

Studies have used various dosages. A commonly studied range is 300-600 mg standardized extract, 30 min before bed. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of バレリアンルート?

Reported side effects may include Headache, Dizziness, GI upset, Morning grogginess. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for バレリアンルート and 入眠困難?

We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 15 total participants. The overall direction of effect is positive.

に関する他の成分：入眠困難

ビタミンB6 A グリシン酸マグネシウム A 亜鉛 A メラトニン A Hops A L-テアニン A

バレリアンルート他の症状・状態について

不眠症 A 不安に伴う睡眠障害 B

総合評価

合計15名の参加者を対象とした5件の研究（メタアナリシス1件、RCT 1件を含む）に基づく。5件中3件の研究で肯定的な効果が示されている。

Evidence Strength72%

High confidence

研究の内訳

RCT (1)Meta (0)Other (4)

代替成分との比較

この症状に対する他の成分との比較をご覧ください。

に関するすべての成分を見る：入眠困難

詳しく見る

References

[1] Kacper Żełabowski et al.. Molecules. 2025. The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, Ramelteon, Agomelatine, and Selected Herbs. doi:10.3390/molecules30183814 PubMed
[2] Oliviero Bruni et al.. Nutrients. 2021. Herbal Remedies and Their Possible Effect on the GABAergic System and Sleep. doi:10.3390/nu13020530 PubMed
[3] Vivien C Abad et al.. Drugs Aging. 2018. Insomnia in Elderly Patients: Recommendations for Pharmacological Management. doi:10.1007/s40266-018-0569-8 PubMed
[4] Michael J Sateia et al.. J Clin Sleep Med. 2017. Clinical Practice Guideline for the Pharmacologic Treatment of Chronic Insomnia in Adults: An American Academy of Sleep Medicine Clinical Practice … doi:10.5664/jcsm.6470 PubMed
[5] Wilfred R Pigeon et al.. J Med Food. 2010. Effects of a tart cherry juice beverage on the sleep of older adults with insomnia: a pilot study. doi:10.1089/jmf.2009.0096 PubMed

FDAに関する免責事項: これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

バレリアンルート ： 入眠困難