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アシュワガンダ ： 不安に伴う睡眠障害

B

3件の研究（メタアナリシス2件を含む）に基づく。3件中3件の研究で肯定的な効果が示されている。

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            B

        

        

            
結論

            
            
Ashwagandha may help improve sleep that is disrupted by anxiety, with consistent positive findings from multiple reviews, though more research would strengthen the evidence.

            
            
            
    
                
                
  • 
                    
                    All 3 studies, including 2 meta-analyses, report positive effects
                
    • 
                
                
  • 
                    
                    Ashwagandha appears to work through GABA-modulating pathways that reduce anxiety
                
    • 
                
                
  • 
                    
                    Research spans systematic reviews and meta-analyses of existing clinical evidence
                
    • 
                
                
  • 
                    
                    Grade B evidence suggests good but not yet conclusive support
                
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Key Study Findings





    

        
        

            

                
                    Meta-Analysis
                
                
                
                
            

            
                Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
            
            

                
                Dose: Various medicinal herbs: Silexan, Kava, Ginkgo biloba, Withania somnifera, Galphimia glauca, Passion
                
                
                vs: Placebo
                
                
                
                効果: Silexan MD -3.84 (95% CrI -6.31 to -1.34); Kava MD -2.46 (95% CrI -4.47 to -0.32); Ginkgo biloba MD 
                
                
                None
                
            

            
        

        
        

            

                
                    Review
                
                
                
                
            

            
                Medicinal Plants for Insomnia Related to Anxiety: An Updated Review.
            
            

                
                Dose: None
                
                
                vs: Placebo
                
                
                
                効果: None
                
                
                None
                
            

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
3

        
研究数

    

    

        
--

        
参加者数

    

    

        
            
            ↑
            
        
        
Positive

    

    

        B

        
グレード

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
                        
                        
                            
                                Meta-Analysis
                            
                            
                            
                        
                    

                    

                        Pharmacological research
                        2022
                        
                        51 件の引用
                        
                    

                

                
                

                    

                        
                            Medicinal Plants for Insomnia Related to Anxiety: An Updated Review.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Planta medica
                        2021
                        
                        41 件の引用
                        
                    

                

                
                

                    

                        
                            GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence.
                        
                        
                            
                                Systematic Review
                            
                            
                            
                        
                    

                    

                        Phytotherapy research : …
                        2018
                        
                        95 件の引用
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
一般的な使用量

                

                    
                    

                        
sleep:

                        
300-600 mg KSM-66 or Sensoril, before bed

                    

                    
                

                
                

                    上限量： Not established; studied up to 1,200 mg/day
                

                
            

            

            
            

                
研究で検討された用量

                

                    

                        
                            

                                用量
                                期間
                                効果
                                N
                            

                        
                        
                            
                            

                                Various medicinal herbs: Silexan, Kava, Ginkgo biloba, Withania somnifera, Galphimia glauca, Passion
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                推奨摂取タイミング： 1-2 hours before bed
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
報告されている副作用

                    
    
                        
                        
  • 
                            ⚠
                            Drowsiness
                        
    • 
                        
                        
  • 
                            ⚠
                            GI upset
                        
    • 
                        
                        
  • 
                            ⚠
                            Diarrhea
                        
    • 
                        
                        
  • 
                            ⚠
                            Headache
                        
    • 
                        
                    

                

                

                
                

                    
既知の相互作用

                    
    
                        
                        
  • 
                            ●
                            Thyroid medications — ashwagandha may increase thyroid hormone levels
                        
    • 
                        
                        
  • 
                            ●
                            Immunosuppressants — ashwagandha may stimulate immune activity
                        
    • 
                        
                        
  • 
                            ●
                            Sedatives — potential additive drowsiness
                        
    • 
                        
                        
  • 
                            ●
                            Blood sugar medications — may lower blood glucose
                        
    • 
                        
                    

                

                

                
                

                    

                        耐容上限摂取量： Not established; studied up to 1,200 mg/day
                    

                

                
            

            

                サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does アシュワガンダ help with 不安に伴う睡眠障害?
            
        
        

            Based on 3 studies with 0 participants, there is moderate evidence from clinical studies that アシュワガンダ may support 不安に伴う睡眠障害 management. Our evidence grade is B (Good Evidence).
        

    

    
    

        
            How much アシュワガンダ should I take for 不安に伴う睡眠障害?
            
        
        

            Studies have used various dosages. A commonly studied range is 300-600 mg KSM-66 or Sensoril, before bed. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of アシュワガンダ?
            
        
        

            Reported side effects may include Drowsiness, GI upset, Diarrhea, Headache. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for アシュワガンダ and 不安に伴う睡眠障害?
            
        
        

            We rate the evidence as Grade B (Good Evidence). This rating is based on 3 peer-reviewed studies with 0 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
                

                    
アシュワガンダ 他の症状・状態について

                    

                        
                        
                            不眠症
                            A

                        
                        
                        
                            入眠困難
                            B

                        
                        
                    

                

                
            

        

        

    


    
    












    

        FDAに関する免責事項:
        これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。