Kava के लिए अनिद्रा
A संबंधित साक्ष्य कई बड़े नैदानिक परीक्षण लगातार महत्वपूर्ण लाभ दर्शाते हैं।Based on 34 studies (8 meta-analyses, 1 RCT) with 4,679 total participants. Results are mixed across studies.
निष्कर्ष
Based on 34 studies (8 meta-analyses, 1 RCT) with 4,679 total participants. Results are mixed across studies.
Key Study Findings
जनसंख्या: 41-year-old Australian woman consuming kava for anxiety and insomnia
जनसंख्या: 45-year-old man with kava and kratom withdrawal
जनसंख्या: Adult smokers (trial protocol)
Key Statistics
34
अध्ययन
4679
प्रतिभागी
Mixed
ग्रेड
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
सामान्य रूप से उपयोग की जाने वाली खुराकें
- sleep:
- 120-250 mg kavalactones/day, 1-2 hrs before bed
अधिकतम सीमा: 250 mg kavalactones/day (European guidelines); limited to 3 months continuous use
अनुसंधान में अध्ययन की गई खुराकें
| खुराक | अवधि | प्रभाव | N |
|---|---|---|---|
| None | 6 weeks | Negative | 1 |
| None | -- | Positive | -- |
| None | -- | Positive | 1 |
| varies by supplement | -- | Positive | -- |
| AB-free kava extract | -- | Mixed | -- |
| various | -- | Mixed | 17 |
| None | -- | Mixed | -- |
| Various medicinal herbs: Silexan, Kava, Ginkgo biloba, Withania somnifera, Galphimia glauca, Passion | -- | Positive | -- |
सेवन का सर्वोत्तम समय: 1-2 hours before bed; avoid daily use beyond 3 months without medical supervision
Safety & Side Effects
रिपोर्ट किए गए दुष्प्रभाव
- ⚠ Drowsiness and reduced coordination
- ⚠ Hepatotoxicity (rare but serious — consult healthcare provider)
- ⚠ Skin rash (kava dermopathy) with chronic high-dose use
- ⚠ GI discomfort
ज्ञात अंतःक्रियाएँ
- ● Alcohol — increased hepatotoxicity risk and CNS depression
- ● Hepatotoxic medications (acetaminophen, statins) — additive liver stress
- ● Benzodiazepines and sedatives — additive CNS depression
- ● CYP450 substrates (2E1, 1A2, 2D6) — kavalactones may inhibit metabolism
- ● Levodopa and dopaminergic drugs — kava may reduce efficacy
सहनीय अधिकतम सेवन: 250 mg kavalactones/day (European guidelines); limited to 3 months continuous use
कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।
Frequently Asked Questions
Does Kava help with अनिद्रा?
How much Kava should I take for अनिद्रा?
Are there side effects of Kava?
How strong is the evidence for Kava and अनिद्रा?
Related Evidence
इसके लिए अन्य सामग्री अनिद्रा
Kava अन्य स्वास्थ्य स्थितियों के लिए
References
- [1] Ali Abid et al.. Med J Aust. 2026. Diagnosing Acute Kava Dermopathy: A Case Report of a Characteristic Cutaneous Eruption. doi:10.5694/mja2.70120 PubMed
- [2] Yasmina M Ebrahim et al.. Naunyn Schmiedebergs Arch Pharmacol. 2025. Integrative sleep management: from molecular pathways to conventional and herbal treatments. doi:10.1007/s00210-025-04183-y PubMed
- [3] William Bleifuss et al.. Am J Emerg Med. 2025. Severe kava withdrawal managed with phenobarbital. doi:10.1016/j.ajem.2025.06.016 PubMed
- [4] Ji Won Yeom et al.. Psychiatry Investig. 2024. Herbal and Natural Supplements for Improving Sleep: A Literature Review. doi:10.30773/pi.2024.0121 PubMed
- [5] Chengguo Xing et al.. BMC Complement Med Ther. 2024. The potential of AB-free kava in enabling tobacco cessation via management of abstinence-related stress and insomnia: study protocol for a … doi:10.1186/s12906-024-04722-9 PubMed
- [6] Fei-Yi Zhao et al.. Front Public Health. 2023. Identifying complementary and alternative medicine recommendations for insomnia treatment and care: a systematic review and critical assessment of comprehensive clinical … doi:10.3389/fpubh.2023.1157419 PubMed
- [7] Wenting Zhang et al.. Pharmacol Res. 2022. Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis. doi:10.1016/j.phrs.2022.106204 PubMed
- [8] Rita B Soares et al.. J Clin Med. 2022. An Updated Review on the Psychoactive, Toxic and Anticancer Properties of Kava. doi:10.3390/jcm11144039 PubMed
- [9] Kanika Verma et al.. Cureus. 2022. The Impact of Complementary and Alternative Medicine on Insomnia: A Systematic Review. doi:10.7759/cureus.28425 PubMed
- [10] Juliana Veloso Ferreira et al.. Nat Prod Res. 2022. Acute oral toxicity, antinociceptive and antimicrobial activities of kava dried extracts and synthetic kavain. doi:10.1080/14786419.2021.1973459 PubMed
- [11] Deana Goldin et al.. J Psychosoc Nurs Ment Health Serv. 2022. Calm Down With Kava: What Clinicians Need to Know. doi:10.3928/02793695-20220523-02 PubMed
- [12] Ruhi Ali et al.. Comb Chem High Throughput Screen. 2021. Nutraceuticals for Sleep Disorders. doi:10.2174/1386207324666210121111446 PubMed
- [13] Jennifer L Martin et al.. J Clin Sleep Med. 2020. The Veterans Administration and Department of Defense clinical practice guidelines for the diagnosis and management of sleep disorders: what does … doi:10.5664/jcsm.8486 PubMed
- [14] Pengcheng Wang et al.. Chem Res Toxicol. 2019. Enzymes and Pathways of Kavain Bioactivation and Biotransformation. doi:10.1021/acs.chemrestox.9b00098 PubMed
- [15] Karen Savage et al.. Phytother Res. 2018. GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence. doi:10.1002/ptr.5940 PubMed
- [16] Jungyoon Kim et al.. J Med Food. 2018. Natural Products from Single Plants as Sleep Aids: A Systematic Review. doi:10.1089/jmf.2017.4064 PubMed
- [17] Matthew J Leach et al.. Sleep Med Rev. 2015. Herbal medicine for insomnia: A systematic review and meta-analysis. doi:10.1016/j.smrv.2014.12.003 PubMed
- [18] Stephanie Maxine Ross. Holist Nurs Pract. 2014. Psychophytomedicine: an overview of clinical efficacy and phytopharmacology for treatment of depression, anxiety and insomnia. doi:10.1097/HNP.0000000000000040 PubMed
- [19] Anthony Rowe et al.. Adv Pharmacol Sci. 2011. Toxicokinetics of kava. doi:10.1155/2011/326724 PubMed
- [20] Shaheen E Lakhan et al.. Nutr J. 2010. Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review. doi:10.1186/1475-2891-9-42 PubMed
- [21] Ping Zhou et al.. FASEB J. 2010. Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-kappaB and MAPK signaling pathways. doi:10.1096/fj.10-163311 PubMed
- [22] Benjamin S Weeks. Med Sci Monit. 2009. Formulations of dietary supplements and herbal extracts for relaxation and anxiolytic action: Relarian. PubMed
- [23] David Wheatley. J Psychopharmacol. 2005. Medicinal plants for insomnia: a review of their pharmacology, efficacy and tolerability. doi:10.1177/0269881105053309 PubMed
- [24] Bradly P Jacobs et al.. Medicine (Baltimore). 2005. An internet-based randomized, placebo-controlled trial of kava and valerian for anxiety and insomnia. doi:10.1097/01.md.0000172299.72364.95 PubMed
- [25] Kazuaki Shinomiya et al.. Psychopharmacology (Berl). 2005. Effects of kava-kava extract on the sleep-wake cycle in sleep-disturbed rats. doi:10.1007/s00213-005-2196-4 PubMed
- [26] Amy Lynn Meolie et al.. J Clin Sleep Med. 2005. Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence. PubMed
- [27] Keith I Block et al.. Integr Cancer Ther. 2004. Safety and efficacy of herbal sedatives in cancer care. doi:10.1177/1534735404265003 PubMed
- [28] Sheree Cairney et al.. Hum Psychopharmacol. 2003. Saccade and cognitive impairment associated with kava intoxication. doi:10.1002/hup.532 PubMed
- [29] Michele M Larzelere et al.. Prim Care. 2002. Anxiety, depression, and insomnia. doi:10.1016/s0095-4543(01)00003-3 PubMed
- [30] Ka Fai Chung et al.. Gen Hosp Psychiatry. 2002. Over-the-counter sleeping pills: a survey of use in Hong Kong and a review of their constituents. doi:10.1016/s0163-8343(02)00210-4 PubMed
- [31] D Wheatley. Phytother Res. 2001. Kava and valerian in the treatment of stress-induced insomnia. doi:10.1002/ptr.840 PubMed
- [32] David Wheatley. Hum Psychopharmacol. 2001. Stress-induced insomnia treated with kava and valerian: singly and in combination. doi:10.1002/hup.299 PubMed
- [33] R P Brown et al.. J Psychiatr Pract. 2001. Herbs and nutrients in the treatment of depression, anxiety, insomnia, migraine, and obesity. doi:10.1097/00131746-200103000-00002 PubMed
- [34] A Fugh-Berman et al.. Psychosom Med. 1999. Dietary supplements and natural products as psychotherapeutic agents. doi:10.1097/00006842-199909000-00012 PubMed
- [35] R Süss et al.. Hautarzt. 1996. [Hematogenous contact eczema cause by phytogenic drugs exemplified by kava root extract]. doi:10.1007/s001050050451 PubMed
FDA अस्वीकरण: इन कथनों का Food and Drug Administration द्वारा मूल्यांकन नहीं किया गया है। इस वेबसाइट पर उत्पादों और जानकारी का उद्देश्य किसी बीमारी का निदान, उपचार, इलाज या रोकथाम नहीं है। प्रस्तुत साक्ष्य ग्रेड प्रकाशित पीयर-रिव्यूड अनुसंधान के हमारे विश्लेषण पर आधारित हैं और चिकित्सा सलाह नहीं हैं। कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।