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Kava için Uykusuzluk

A

Based on 34 studies (8 meta-analyses, 1 RCT) with 4,679 total participants. Results are mixed across studies.

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A

Sonuç

Based on 34 studies (8 meta-analyses, 1 RCT) with 4,679 total participants. Results are mixed across studies.

Key Study Findings

Case Reports n=1 6 weeks
Diagnosing Acute Kava Dermopathy: A Case Report of a Characteristic Cutaneous Eruption.
Dose: None vs: None Outcome: acute kava dermopathy with sebaceous gland necrosis Etki: None None

Popülasyon: 41-year-old Australian woman consuming kava for anxiety and insomnia

Case Reports n=1 Open-label
Severe kava withdrawal managed with phenobarbital.
Dose: None vs: None Outcome: Resolution of kava withdrawal symptoms Etki: None None

Popülasyon: 45-year-old man with kava and kratom withdrawal

narrative review
Herbal and Natural Supplements for Improving Sleep: A Literature Review.
Dose: varies by supplement vs: Placebo Etki: None None
Other Double-blind
The potential of AB-free kava in enabling tobacco cessation via management of abstinence-related stress and …
Dose: AB-free kava extract vs: Placebo Outcome: Tobacco cessation via stress/insomnia management Etki: None None

Popülasyon: Adult smokers (trial protocol)

Key Statistics

34

Çalışmalar

4679

Katılımcılar

Mixed

A

Derece

Referenced Papers

The American journal … 2025 1 atıf
Journal of psychosocial … 2022 2 atıf
Combinatorial chemistry & … 2021 16 atıf
Journal of medicinal … 2018 19 atıf
Sleep medicine reviews 2015 152 atıf
Advances in pharmacological … 2011 79 atıf
Integrative cancer therapies 2004 59 atıf
Primary care 2002 43 atıf
Phytotherapy research : … 2001 74 atıf

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Yaygın Kullanılan Dozajlar

sleep:
120-250 mg kavalactones/day, 1-2 hrs before bed

Üst sınır: 250 mg kavalactones/day (European guidelines); limited to 3 months continuous use

Araştırmalarda İncelenen Dozajlar

Dozaj Süre Etki N
None 6 weeks Negative 1
None -- Positive --
None -- Positive 1
varies by supplement -- Positive --
AB-free kava extract -- Mixed --
various -- Mixed 17
None -- Mixed --
Various medicinal herbs: Silexan, Kava, Ginkgo biloba, Withania somnifera, Galphimia glauca, Passion -- Positive --

En iyi alım zamanı: 1-2 hours before bed; avoid daily use beyond 3 months without medical supervision

Safety & Side Effects

Bildirilen Yan Etkiler

  • Drowsiness and reduced coordination
  • Hepatotoxicity (rare but serious — consult healthcare provider)
  • Skin rash (kava dermopathy) with chronic high-dose use
  • GI discomfort

Bilinen Etkileşimler

  • Alcohol — increased hepatotoxicity risk and CNS depression
  • Hepatotoxic medications (acetaminophen, statins) — additive liver stress
  • Benzodiazepines and sedatives — additive CNS depression
  • CYP450 substrates (2E1, 1A2, 2D6) — kavalactones may inhibit metabolism
  • Levodopa and dopaminergic drugs — kava may reduce efficacy

Tolere edilebilir üst alım: 250 mg kavalactones/day (European guidelines); limited to 3 months continuous use

Herhangi bir takviye kullanmaya başlamadan önce mutlaka sağlık uzmanınıza danışın.Herhangi bir takviye başlatmadan önce her zaman sağlık uzmanınıza danışın.

Frequently Asked Questions

Does Kava help with Uykusuzluk?
Based on 34 studies with 4,679 participants, there is strong evidence from multiple clinical trials that Kava may support Uykusuzluk management. Our evidence grade is A (Strong Evidence).
How much Kava should I take for Uykusuzluk?
Studies have used various dosages. A commonly studied range is 120-250 mg kavalactones/day, 1-2 hrs before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Kava?
Reported side effects may include Drowsiness and reduced coordination, Hepatotoxicity (rare but serious — consult healthcare provider), Skin rash (kava dermopathy) with chronic high-dose use, GI discomfort. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Kava and Uykusuzluk?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 34 peer-reviewed studies with 4,679 total participants. The overall direction of effect is mixed.

Related Evidence

FDA Sorumluluk Reddi: Bu ifadeler Gıda ve İlaç Dairesi (FDA) tarafından değerlendirilmemiştir. Bu web sitesindeki ürünler ve bilgiler herhangi bir hastalığı teşhis etmek, tedavi etmek, iyileştirmek veya önlemek amacıyla tasarlanmamıştır. Sunulan kanıt dereceleri, yayımlanmış hakemli araştırmalarımızın analizine dayanmaktadır ve tıbbi tavsiye niteliği taşımamaktadır. Herhangi bir takviye rejimine başlamadan önce her zaman sağlık uzmanınıza danışın.