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Kava para Insônia

A

Based on 34 studies (8 meta-analyses, 1 RCT) with 4,679 total participants. Results are mixed across studies.

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A

Conclusão

Based on 34 studies (8 meta-analyses, 1 RCT) with 4,679 total participants. Results are mixed across studies.

Key Study Findings

Case Reports n=1 6 weeks
Diagnosing Acute Kava Dermopathy: A Case Report of a Characteristic Cutaneous Eruption.
Dose: None vs: None Outcome: acute kava dermopathy with sebaceous gland necrosis Efeito: None None

População: 41-year-old Australian woman consuming kava for anxiety and insomnia

Case Reports n=1 Open-label
Severe kava withdrawal managed with phenobarbital.
Dose: None vs: None Outcome: Resolution of kava withdrawal symptoms Efeito: None None

População: 45-year-old man with kava and kratom withdrawal

narrative review
Herbal and Natural Supplements for Improving Sleep: A Literature Review.
Dose: varies by supplement vs: Placebo Efeito: None None
Other Double-blind
The potential of AB-free kava in enabling tobacco cessation via management of abstinence-related stress and …
Dose: AB-free kava extract vs: Placebo Outcome: Tobacco cessation via stress/insomnia management Efeito: None None

População: Adult smokers (trial protocol)

Key Statistics

34

Estudos

4679

Participantes

Mixed

A

Nota

Referenced Papers

Naunyn-Schmiedeberg's archives of … 2025 4 citações
The American journal … 2025 1 citações
Psychiatry investigation 2024 24 citações
Journal of psychosocial … 2022 2 citações
Combinatorial chemistry & … 2021 16 citações
Chemical research in … 2019 6 citações
Journal of medicinal … 2018 19 citações
Sleep medicine reviews 2015 152 citações
Advances in pharmacological … 2011 79 citações
Journal of psychopharmacology … 2005 176 citações
Integrative cancer therapies 2004 59 citações
Human psychopharmacology 2003 45 citações
Primary care 2002 43 citações
Phytotherapy research : … 2001 74 citações
Psychosomatic medicine 1999 136 citações
Der Hautarzt; Zeitschrift … 1996 22 citações

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosagens Comumente Utilizadas

sleep:
120-250 mg kavalactones/day, 1-2 hrs before bed

Limite superior: 250 mg kavalactones/day (European guidelines); limited to 3 months continuous use

Dosagens Estudadas em Pesquisas

Dosagem Duração Efeito N
None 6 weeks Negative 1
None -- Positive --
None -- Positive 1
varies by supplement -- Positive --
AB-free kava extract -- Mixed --
various -- Mixed 17
None -- Mixed --
Various medicinal herbs: Silexan, Kava, Ginkgo biloba, Withania somnifera, Galphimia glauca, Passion -- Positive --

Melhor horário: 1-2 hours before bed; avoid daily use beyond 3 months without medical supervision

Safety & Side Effects

Efeitos Colaterais Relatados

  • Drowsiness and reduced coordination
  • Hepatotoxicity (rare but serious — consult healthcare provider)
  • Skin rash (kava dermopathy) with chronic high-dose use
  • GI discomfort

Interações Conhecidas

  • Alcohol — increased hepatotoxicity risk and CNS depression
  • Hepatotoxic medications (acetaminophen, statins) — additive liver stress
  • Benzodiazepines and sedatives — additive CNS depression
  • CYP450 substrates (2E1, 1A2, 2D6) — kavalactones may inhibit metabolism
  • Levodopa and dopaminergic drugs — kava may reduce efficacy

Ingestão máxima tolerável: 250 mg kavalactones/day (European guidelines); limited to 3 months continuous use

Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.

Frequently Asked Questions

Does Kava help with Insônia?
Based on 34 studies with 4,679 participants, there is strong evidence from multiple clinical trials that Kava may support Insônia management. Our evidence grade is A (Strong Evidence).
How much Kava should I take for Insônia?
Studies have used various dosages. A commonly studied range is 120-250 mg kavalactones/day, 1-2 hrs before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Kava?
Reported side effects may include Drowsiness and reduced coordination, Hepatotoxicity (rare but serious — consult healthcare provider), Skin rash (kava dermopathy) with chronic high-dose use, GI discomfort. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Kava and Insônia?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 34 peer-reviewed studies with 4,679 total participants. The overall direction of effect is mixed.

Related Evidence

Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.