Tryptophan için Uykusuzluk

References

1. [1] E Hartmann. J Psychiatr Res. Effects of L-tryptophan on sleepiness and on sleep. doi:10.1016/0022-3956(82)90012-7 PubMed
2. [2] Xin Teng et al.. J Ethnopharmacol. 2026. Chaihu-Jia-Longgu-Muli Decoction improves dizziness with anxiety in rats by modulating tryptophan metabolism. doi:10.1016/j.jep.2025.120881 PubMed
3. [3] Liuyan Zhu et al.. Biomedicines. 2026. Serum Amino Acid and Fatty Acid Metabolites as Predictors of Sleep Disorders in Children: A Risk Prediction Model. doi:10.3390/biomedicines14030546 PubMed
4. [4] Qiong Wu et al.. Food Funct. 2026. Bifidobacterium animalis subsp. lactis Bbm-19 ameliorates insomnia by remodeling the gut microbiota and restoring γ-aminobutyric acid and serotonin signaling. doi:10.1039/d5fo04374c PubMed
5. [5] Yi Shu et al.. Phytomedicine. 2026. Compound Chaijin Jieyu Fang alleviates insomnia complicated with depression by reshaping actinobacteria to inhibit neuronal apoptosis. doi:10.1016/j.phymed.2025.157632 PubMed
6. [6] Rui Li et al.. J Ethnopharmacol. 2025. Flavonoids from mulberry leaves exhibit sleep-improving effects via regulating GABA and 5-HT receptors. doi:10.1016/j.jep.2024.118734 PubMed
7. [7] Wanying Zhai et al.. Asian Pac J Allergy Immunol. 2025. Efficacy and associated neurotransmitters of digital cognitive behavior therapy for atopic dermatitis: A comparative effectiveness research. doi:10.12932/AP-100223-1542 PubMed
8. [8] Jingyi Li et al.. Psychopharmacology (Berl). 2025. Ginsenoside Rg1 alleviates PCPA-induced insomnia by inhibiting NLRP3 inflammasome activation and pyroptosis through the Nrf2/HO-1 pathway in mice. doi:10.1007/s00213-025-06828-5 PubMed
9. [9] Yuan Tian et al.. Phytomedicine. 2025. Wendan Decoction exerts therapeutic effects on insomnia by regulating gut microbiota and tryptophan metabolism. doi:10.1016/j.phymed.2025.157028 PubMed
10. [10] Shangwen Qi et al.. Front Microbiol. 2025. Effect of acupuncture at Back-Shu points on gut microbiota in insomnia model rats based on metagenomic sequencing technology. doi:10.3389/fmicb.2025.1541958 PubMed
11. [11] Jolijn Boer et al.. J Clin Sleep Med. 2025. Effect of graduated drug therapy for moderate-to-severe chronic insomnia on the severity of disease: an observational study in Germany. doi:10.5664/jcsm.11334 PubMed
12. [12] Peifan Li et al.. Microbiol Res. 2025. Lactobacillales derived from traditional Xizang dairy products improve insomnia and restore neurotransmitter-metabolic profiles via gut microbiota in PCPA-induced mice. doi:10.1016/j.micres.2025.128276 PubMed
13. [13] Zirong Li et al.. Neurosci Lett. 2025. Sleep deprivation activated AMPK/FOXO3a signaling mediates pineal autophagy impairment to reduce melatonin secretion in CUMS + SD rats leading to … doi:10.1016/j.neulet.2024.138091 PubMed
14. [14] Wedad S Sarawi. Mol Neurobiol. 2025. Neurochemical Insights into the Role of Tryptophan Metabolites and Kynurenine Pathway in Insomnia and its Psychological and Neurological Comorbidities. doi:10.1007/s12035-025-05210-y PubMed
15. [15] Antonios Liaskopoulos et al.. Sleep Sci. 2025. Medical Professionals and Pharmacological Intervention for the Treatment of Insomnia: A Cross-Sectional Study. doi:10.1055/s-0044-1791238 PubMed
16. [16] Xiaona Ye et al.. Int Immunopharmacol. 2025. Promotion of sleep by cinnamic acid in parachlorophenylalanine-induced insomnia in rats. doi:10.1016/j.intimp.2025.114852 PubMed
17. [17] Lin Gao et al.. Int J Biol Macromol. 2025. Construction of composite nanoparticles of β-cyclodextrin and corn starch encapsulating 5-hydroxytryptophan for sustained release and sleep improvement in vivo. doi:10.1016/j.ijbiomac.2025.140831 PubMed
18. [18] Yuxuan Liang et al.. Int J Biol Macromol. 2025. The role of molecular weight on chitosan and chitosan oligosaccharides in sleep regulation: Integrating network pharmacology and multi-omics analysis in … doi:10.1016/j.ijbiomac.2025.142147 PubMed
19. [19] Xin-Yu Li et al.. Sci Rep. 2025. Tryptophan metabolism-related gene CYP1B1 serves as a shared biomarker for both Parkinson's disease and insomnia. doi:10.1038/s41598-024-84362-8 PubMed
20. [20] Tatiana Palotta Minari et al.. Sleep Breath. 2025. Unraveling the connection between the Mediterranean diet and sleep health: from biological mechanisms to clinical implications. doi:10.1007/s11325-025-03546-2 PubMed
21. [21] Jun-Hang Hu et al.. Zhongguo Zhong Yao Za Zhi. 2025. [Effect of Fushen Decoction on 5-HT system and GABA expression in mouse model of PCPA-induced insomnia]. doi:10.19540/j.cnki.cjcmm.20241101.401 PubMed
22. [22] Wing-Yan Wong et al.. Food Funct. 2025. A non-pharmacological intervention for insomnia: tryptophan-fructooligosaccharides combination improves sleep in mice via anti-inflammation and gut microbiota modulation. doi:10.1039/d5fo01651g PubMed
23. [23] Chunhong Zhang et al.. Front Microbiol. 2025. Characteristics and influencing factors of gut microbiota in population with sleep disorders. doi:10.3389/fmicb.2025.1586864 PubMed
24. [24] Shihao Zhang et al.. BMC Complement Med Ther. 2025. Integrating serum pharmacochemistry with network pharmacology and pharmacological validation to elucidate the mechanism of KaiXinSan in treating insomnia. doi:10.1186/s12906-025-05196-z PubMed
25. [25] Rosa M Ortega et al.. Nutr Hosp. 2025. [Nutrition in improving sleep quality and fighting insomnia]. doi:10.20960/nh.06090 PubMed
26. [26] Xinying Fu et al.. J Ethnopharmacol. 2024. Guhan Yangsheng Jing mitigates hippocampal neuronal pyroptotic injury and manifies learning and memory capabilities in sleep deprived mice via the … doi:10.1016/j.jep.2024.117972 PubMed
27. [27] Ji Won Yeom et al.. Psychiatry Investig. 2024. Herbal and Natural Supplements for Improving Sleep: A Literature Review. doi:10.30773/pi.2024.0121 PubMed
28. [28] Waseem Dar. Int Immunopharmacol. 2024. Aspartame-induced cognitive dysfunction: Unveiling role of microglia-mediated neuroinflammation and molecular remediation. doi:10.1016/j.intimp.2024.112295 PubMed
29. [29] Yu-Meng Liu et al.. Neurochem Res. 2024. Cannabidiol Exerts Sedative and Hypnotic Effects in Normal and Insomnia Model Mice Through Activation of 5-HT1A Receptor. doi:10.1007/s11064-024-04102-2 PubMed
30. [30] Meng Yu et al.. Carbohydr Polym. 2024. A novel antidepressant homogeneous polysaccharide YLP-1 from Millettia pulchra ameliorates tryptophan metabolism and SCFAs through modulating gut microbiota. doi:10.1016/j.carbpol.2024.122527 PubMed
31. [31] Haiqin Ren et al.. J Ethnopharmacol. 2024. The therapeutic potential of Ziziphi Spinosae Semen and Polygalae Radix in insomnia management: Insights from gut microbiota and serum metabolomics … doi:10.1016/j.jep.2024.118255 PubMed
32. [32] Tian-Ji Xia et al.. J Ethnopharmacol. 2024. Shen Yuan extract exerts a hypnotic effect via the tryptophan/5-hydroxytryptamine/melatonin pathway in mice. doi:10.1016/j.jep.2024.117992 PubMed
33. [33] Xinyuan Xie et al.. BMC Womens Health. 2024. Study on gut microbiota and metabolomics in postmenopausal women. doi:10.1186/s12905-024-03448-7 PubMed
34. [34] Yingxin Chu et al.. Biomed Chromatogr. 2024. An integrated liver, hippocampus and serum metabolomics based on UPLC-Q-TOF-MS revealed the therapeutical mechanism of Ziziphi Spinosae Semen in p-chlorophenylalanine-induced … doi:10.1002/bmc.5796 PubMed
35. [35] María Morales-Suárez-Varela et al.. Nutrients. 2024. Sleep Patterns and Tryptophan Consumption among Students at Spanish Universities: The Unihcos Project. doi:10.3390/nu16142376 PubMed
36. [36] Silvia Pérez-Piñero et al.. Clocks Sleep. 2024. Effectiveness of Enriched Milk with Ashwagandha Extract and Tryptophan for Improving Subjective Sleep Quality in Adults with Sleep Problems: A … doi:10.3390/clockssleep6030028 PubMed
37. [37] Chenhui Du et al.. Biomed Chromatogr. 2024. Study on the antidepressive effects and mechanism of raw and fried Ziziphi Spinosae Semen via metabolomics and gut microbiota analysis. doi:10.1002/bmc.5873 PubMed
38. [38] Hsin-Chieh Kung et al.. Int J Mol Sci. 2024. Biosynthetic Pathways of Tryptophan Metabolites in Saccharomyces cerevisiae Strain: Insights and Implications. doi:10.3390/ijms25094747 PubMed
39. [39] Muteber Gizem Keser et al.. Asia Pac J Clin Nutr. 2024. Bedtime banana and milk intake on sleep and biochemical parameters. doi:10.6133/apjcn.202412_33(4).0002 PubMed
40. [40] Yan Yan et al.. Phytomedicine. 2023. Screening the effective components of Suanzaoren decoction on the treatment of chronic restraint stress induced anxiety-like mice by integrated chinmedomics … doi:10.1016/j.phymed.2023.154853 PubMed
41. [41] Cezary Chojnacki et al.. Nutrients. 2023. Beneficial Effect of Increased Tryptophan Intake on Its Metabolism and Mental State of the Elderly. doi:10.3390/nu15040847 PubMed
42. [42] Tian-Ji Xia et al.. Front Pharmacol. 2023. Melatonin-related dysfunction in chronic restraint stress triggers sleep disorders in mice. doi:10.3389/fphar.2023.1210393 PubMed
43. [43] Deepika Singh et al.. Bioorg Chem. 2023. Development and challenges in the discovery of 5-HT1A and 5-HT7 receptor ligands. doi:10.1016/j.bioorg.2022.106254 PubMed
44. [44] Alice Innocenti et al.. Int J Mol Sci. 2023. The Role of Supplements and Over-the-Counter Products to Improve Sleep in Children: A Systematic Review. doi:10.3390/ijms24097821 PubMed
45. [45] Edgar Specker et al.. J Med Chem. 2023. Structure-Based Design of Xanthine-Imidazopyridines and -Imidazothiazoles as Highly Potent and In Vivo Efficacious Tryptophan Hydroxylase Inhibitors. doi:10.1021/acs.jmedchem.3c01454 PubMed
46. [46] Nedjma Labani et al.. Pharmaceutics. 2023. Pistacia vera Extract Potentiates the Effect of Melatonin on Human Melatonin MT1 and MT2 Receptors with Functional Selectivity. doi:10.3390/pharmaceutics15071845 PubMed
47. [47] Swapna N Deshpande et al.. Child Adolesc Psychiatr Clin N Am. 2023. Complementary and Integrative Approaches to Sleep Disorders in Children. doi:10.1016/j.chc.2022.08.008 PubMed
48. [48] Talia Piater et al.. J Pers Med. 2023. Persistent Symptoms and IFN-γ-Mediated Pathways after COVID-19. doi:10.3390/jpm13071055 PubMed
49. [49] Nicole Pesantes et al.. Front Microbiol. 2023. Influence of mental health medication on microbiota in the elderly population in the Valencian region. doi:10.3389/fmicb.2023.1094071 PubMed
50. [50] Clarinda N Sutanto et al.. Nutr Rev. 2022. The impact of tryptophan supplementation on sleep quality: a systematic review, meta-analysis, and meta-regression. doi:10.1093/nutrit/nuab027 PubMed
51. [51] Yanpo Si et al.. Neurochem Res. 2022. Comprehensive 16S rDNA Sequencing and LC-MS/MS-Based Metabolomics to Investigate Intestinal Flora and Metabolic Profiles of the Serum, Hypothalamus and Hippocampus … doi:10.1007/s11064-021-03466-z PubMed
52. [52] Zhen Zhang et al.. Microb Cell Fact. 2022. Metabolic engineering of Escherichia coli for efficient production of L-5-hydroxytryptophan from glucose. doi:10.1186/s12934-022-01920-3 PubMed
53. [53] Cezary Chojnacki et al.. Int J Mol Sci. 2022. A Reduced Tryptophan Diet in Patients with Diarrhoea-Predominant Irritable Bowel Syndrome Improves Their Abdominal Symptoms and Their Quality of Life … doi:10.3390/ijms232315314 PubMed
54. [54] Zhen-Hua Bian et al.. Zhongguo Zhong Yao Za Zhi. 2022. [Effective substance and mechanism of Ziziphi Spinosae Semen extract in treatment of insomnia based on serum metabolomics and network pharmacology]. doi:10.19540/j.cnki.cjcmm.20210922.702 PubMed
55. [55] D E Alcantara-Zapata et al.. Front Physiol. 2022. Women's mood at high altitude. sexual dimorphism in hypoxic stress modulation by the tryptophan-melatonin axis. doi:10.3389/fphys.2022.1099276 PubMed
56. [56] Hongda Liu et al.. Front Pharmacol. 2022. Evaluation of the pharmacological effects and exploration of the mechanism of traditional Chinese medicine preparation Ciwujia tablets in treating insomnia … doi:10.3389/fphar.2022.1009668 PubMed
57. [57] He DU et al.. Zhongguo Zhong Yao Za Zhi. 2022. [Mechanism of Suanzaoren Decoction in improving insomnia rats by integrating metabolomics and intestinal flora analysis]. doi:10.19540/j.cnki.cjcmm.20220902.701 PubMed
58. [58] Faris M Zuraikat et al.. Annu Rev Nutr. 2021. Sleep and Diet: Mounting Evidence of a Cyclical Relationship. doi:10.1146/annurev-nutr-120420-021719 PubMed
59. [59] Xin-Xin Liu et al.. Front Bioeng Biotechnol. 2021. Advances in the Microbial Synthesis of 5-Hydroxytryptophan. doi:10.3389/fbioe.2021.624503 PubMed
60. [60] Ruhi Ali et al.. Comb Chem High Throughput Screen. 2021. Nutraceuticals for Sleep Disorders. doi:10.2174/1386207324666210121111446 PubMed
61. [61] Paolo Curatolo et al.. Nutrients. 2021. Use of Nutraceutical Ingredient Combinations in the Management of Tension-Type Headaches with or without Sleep Disorders. doi:10.3390/nu13051631 PubMed
62. [62] Ovidio Hernando-Requejo et al.. Nutr Hosp. 2021. [Nutrition impact on insomnia treatment]. doi:10.20960/nh.03359 PubMed
63. [63] Johanna Peña Vivas et al.. Nutr Hosp. 2021. [L-tryptophan as dietetic supplement and treatment for hot flashes, astenia, and insomnia in cancer patients]. doi:10.20960/nh.03404 PubMed
64. [64] Da Xu et al.. Appl Microbiol Biotechnol. 2020. Enhanced production of 5-hydroxytryptophan through the regulation of L-tryptophan biosynthetic pathway. doi:10.1007/s00253-020-10371-y PubMed
65. [65] Jintana Sangsopha et al.. J Food Sci Technol. 2020. Dietary sources of melatonin and benefits from production of high melatonin pasteurized milk. doi:10.1007/s13197-020-04236-5 PubMed
66. [66] Oliviero Bruni et al.. Expert Opin Pharmacother. 2019. Pharmacotherapeutic management of sleep disorders in children with neurodevelopmental disorders. doi:10.1080/14656566.2019.1674283 PubMed
67. [67] Sang-Seo Park et al.. J Exerc Rehabil. 2019. Treadmill exercise ameliorates nicotine withdrawal-induced symptoms. doi:10.12965/jer.1938228.114 PubMed
68. [68] Aurora E Serralde-Zúñiga et al.. Cochrane Database Syst Rev. 2019. Fluoxetine for adults who are overweight or obese. doi:10.1002/14651858.CD011688.pub2 PubMed
69. [69] Ning Mou et al.. RSC Adv. 2019. Study on the hypnotic effect of rare protopanaxadiol-type and protopanaxatriol-type ginsenosides. doi:10.1039/c9ra01549c PubMed
70. [70] Vivien C Abad et al.. Drugs Aging. 2018. Insomnia in Elderly Patients: Recommendations for Pharmacological Management. doi:10.1007/s40266-018-0569-8 PubMed
71. [71] Jack N Losso et al.. Am J Ther. 2018. Pilot Study of the Tart Cherry Juice for the Treatment of Insomnia and Investigation of Mechanisms. doi:10.1097/MJT.0000000000000584 PubMed
72. [72] Dahlia Mukherjee et al.. Bipolar Disord. 2018. Total sleep time and kynurenine metabolism associated with mood symptom severity in bipolar disorder. doi:10.1111/bdi.12529 PubMed
73. [73] V Gianfredi et al.. Ann Ig. 2018. Sleep disorder, Mediterranean Diet and learning performance among nursing students: inSOMNIA, a cross-sectional study. doi:10.7416/ai.2018.2247 PubMed
74. [74] Hong-Yan Zhu et al.. RSC Adv. 2018. 4-Hydroxybenzyl alcohol derivatives and their sedative-hypnotic activities. doi:10.1039/c8ra01972j PubMed
75. [75] Ki-Bae Hong et al.. Nutr Res Pract. 2018. Two combined amino acids promote sleep activity in caffeine-induced sleepless model systems. doi:10.4162/nrp.2018.12.3.208 PubMed
76. [76] Feng Mei et al.. Balkan Med J. 2018. The Relationship Between Tryptophan Hydroxylase-2 Gene with Primary Insomnia and Depressive Symptoms in the Han Chinese Population. doi:10.4274/balkanmedj.2017.1406 PubMed
77. [77] Kai-Ming Duan et al.. Metab Brain Dis. 2018. The role of tryptophan metabolism in postpartum depression. doi:10.1007/s11011-017-0178-y PubMed
78. [78] Michael J Sateia et al.. J Clin Sleep Med. 2017. Clinical Practice Guideline for the Pharmacologic Treatment of Chronic Insomnia in Adults: An American Academy of Sleep Medicine Clinical Practice … doi:10.5664/jcsm.6470 PubMed
79. [79] Noreen Samad et al.. Pak J Pharm Sci. 2017. Serum levels of leptin, zinc and tryptophan in obese subjects with sleep deficits. PubMed
80. [80] Harris R Lieberman et al.. J Nutr. 2016. Tryptophan Intake in the US Adult Population Is Not Related to Liver or Kidney Function but Is Associated with Depression … doi:10.3945/jn.115.226969 PubMed
81. [81] Ki-Bae Hong et al.. Life Sci. 2016. Sleep-promoting effects of a GABA/5-HTP mixture: Behavioral changes and neuromodulation in an invertebrate model. doi:10.1016/j.lfs.2016.02.086 PubMed
82. [82] Dongming Wang et al.. Medicine (Baltimore). 2016. Tryptophan for the sleeping disorder and mental symptom of new-type drug dependence: A randomized, double-blind, placebo-controlled trial. doi:10.1097/MD.0000000000004135 PubMed
83. [83] Sangmi Kim et al.. Cancer. 2015. Inflammation-induced activation of the indoleamine 2,3-dioxygenase pathway: Relevance to cancer-related fatigue. doi:10.1002/cncr.29302 PubMed
84. [84] Meng-Fei Ye et al.. Biomed Rep. 2015. Flos Albiziae aqueous extract and its active constituent quercetin potentiate the hypnotic effect of pentobarbital via the serotonergic system. doi:10.3892/br.2015.518 PubMed
85. [85] M O Melancon et al.. Pathol Biol (Paris). 2014. Exercise and sleep in aging: emphasis on serotonin. doi:10.1016/j.patbio.2014.07.004 PubMed
86. [86] Yuheng Lin et al.. ACS Synth Biol. 2014. Engineering bacterial phenylalanine 4-hydroxylase for microbial synthesis of human neurotransmitter precursor 5-hydroxytryptophan. doi:10.1021/sb5002505 PubMed
87. [87] D Dalla Libera et al.. Neurol Sci. 2014. Complementary and alternative medicine (CAM) use in an Italian cohort of pediatric headache patients: the tip of the iceberg. doi:10.1007/s10072-014-1756-y PubMed
88. [88] Cristiane R Macedo et al.. Cochrane Database Syst Rev. 2014. Pharmacotherapy for sleep bruxism. doi:10.1002/14651858.CD005578.pub2 PubMed
89. [89] Chenning Zhang et al.. Eur J Pharmacol. 2014. Pharmacological evaluation of sedative and hypnotic effects of schizandrin through the modification of pentobarbital-induced sleep behaviors in mice. doi:10.1016/j.ejphar.2014.09.012 PubMed
90. [90] Yawen Zeng et al.. Curr Signal Transduct Ther. 2014. Strategies of Functional Foods Promote Sleep in Human Being. doi:10.2174/1574362410666150205165504 PubMed
91. [91] Chenning Zhang et al.. Fitoterapia. 2014. Gomisin N isolated from Schisandra chinensis augments pentobarbital-induced sleep behaviors through the modification of the serotonergic and GABAergic system. doi:10.1016/j.fitote.2014.04.017 PubMed
92. [92] Mónica Flores-Ramos et al.. Gynecol Endocrinol. 2014. Gonadal hormone levels and platelet tryptophan and serotonin concentrations in perimenopausal women with or without depressive symptoms. doi:10.3109/09513590.2013.875994 PubMed
93. [93] Fatmah A M Al-Omary. Profiles Drug Subst Excip Relat Methodol. 2013. Melatonin: comprehensive profile. doi:10.1016/B978-0-12-407691-4.00005-8 PubMed
94. [94] Dingyan Chen et al.. J Huazhong Univ Sci Technolog Med Sci. 2012. Neurotransmitter-precursor-supplement intervention for detoxified heroin addicts. doi:10.1007/s11596-012-0073-z PubMed
95. [95] Sara Baraldi et al.. J Clin Psychopharmacol. 2012. Symptomatic treatment of interferon-α-induced depression in hepatitis C: a systematic review. doi:10.1097/JCP.0b013e31825d9982 PubMed
96. [96] Jerome Sarris et al.. Sleep Med Rev. 2011. A systematic review of insomnia and complementary medicine. doi:10.1016/j.smrv.2010.04.001 PubMed
97. [97] Benjamin S Weeks. Med Sci Monit. 2009. Formulations of dietary supplements and herbal extracts for relaxation and anxiolytic action: Relarian. PubMed
98. [98] George J Trachte et al.. Neuropsychiatr Dis Treat. 2009. Both stimulatory and inhibitory effects of dietary 5-hydroxytryptophan and tyrosine are found on urinary excretion of serotonin and dopamine in … doi:10.2147/ndt.s5040 PubMed
99. [99] Julien Mendlewicz. CNS Drugs. 2009. Disruption of the circadian timing systems: molecular mechanisms in mood disorders. doi:10.2165/11318630-000000000-00000 PubMed
100. [100] Li-En Wang et al.. Pharmacol Biochem Behav. 2008. Spinosin, a C-glycoside flavonoid from semen Zizhiphi Spinozae, potentiated pentobarbital-induced sleep via the serotonergic system. doi:10.1016/j.pbb.2008.03.022 PubMed
101. [101] Subrat Kumar Bhattamisra et al.. J Ethnopharmacol. 2008. Antidepressant activity of standardised extract of Marsilea minuta Linn. doi:10.1016/j.jep.2008.01.012 PubMed
102. [102] Guy Chouinard. J Psychiatry Neurosci. 2006. The search for new off-label indications for antidepressant, antianxiety, antipsychotic and anticonvulsant drugs. PubMed
103. [103] Amy Lynn Meolie et al.. J Clin Sleep Med. 2005. Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence. PubMed
104. [104] Craig Hudson et al.. Nutr Neurosci. 2005. Protein source tryptophan versus pharmaceutical grade tryptophan as an efficacious treatment for chronic insomnia. doi:10.1080/10284150500069561 PubMed
105. [105] Michele M Larzelere et al.. Prim Care. 2002. Anxiety, depression, and insomnia. doi:10.1016/s0095-4543(01)00003-3 PubMed
106. [106] Jun Gao et al.. Brain Res. 2002. Modulation of serotonergic projection from dorsal raphe nucleus to basolateral amygdala on sleep-waking cycle of rats. doi:10.1016/s0006-8993(02)02625-2 PubMed
107. [107] A Balogh. Z Arztl Fortbild Qualitatssich. 2001. [Drug for the treatment of sleep disorders--review]. PubMed
108. [108] S Carranza-Lira et al.. Med Sci Monit. 2000. Melatonin and climactery. PubMed
109. [109] K A Azad et al.. Bangladesh Med Res Counc Bull. 2000. Vegetarian diet in the treatment of fibromyalgia. PubMed
110. [110] A Fugh-Berman et al.. Psychosom Med. 1999. Dietary supplements and natural products as psychotherapeutic agents. doi:10.1097/00006842-199909000-00012 PubMed
111. [111] T C Birdsall. Altern Med Rev. 1998. 5-Hydroxytryptophan: a clinically-effective serotonin precursor. PubMed
112. [112] J H Juhl. Altern Med Rev. 1998. Fibromyalgia and the serotonin pathway. PubMed
113. [113] S Liss et al.. Integr Physiol Behav Sci. 1996. Physiological and therapeutic effects of high frequency electrical pulses. doi:10.1007/BF02699781 PubMed
114. [114] S H Onen et al.. Presse Med. 1994. [Prevention and treatment of sleep disorders through regulation] of sleeping habits]. PubMed
115. [115] M Touret et al.. Exp Brain Res. 1991. The role of 5-hydroxytryptophan (5-HTP) in the regulation of the sleep/wake cycle in parachlorophenylalanine (p-CPA) pretreated rat: a multiple approach … doi:10.1007/BF00231046 PubMed
116. [116] R W Fuller. J Clin Psychiatry. 1991. Role of serotonin in therapy of depression and related disorders. PubMed
117. [117] J C Butler et al.. Wis Med J. 1990. Eosinophilia-myalgia syndrome in Wisconsin. PubMed
118. [118] R M Silver et al.. N Engl J Med. 1990. Scleroderma, fasciitis, and eosinophilia associated with the ingestion of tryptophan. doi:10.1056/NEJM199003293221302 PubMed
119. [119] K Demisch et al.. Pharmacopsychiatry. 1987. Treatment of severe chronic insomnia with L-tryptophan and varying sleeping times. doi:10.1055/s-2007-1017115 PubMed
120. [120] J F Pagel. Am Fam Physician. 1987. Diagnosis and treatment of insomnia. PubMed
121. [121] D Schneider-Helmert et al.. Psychopharmacology (Berl). 1986. Evaluation of L-tryptophan for treatment of insomnia: a review. doi:10.1007/BF00175180 PubMed
122. [122] L J Fitten et al.. J Am Geriatr Soc. 1985. L-tryptophan as a hypnotic in special patients. doi:10.1111/j.1532-5415.1985.tb07120.x PubMed
123. [123] R L Williams et al.. Hosp Community Psychiatry. 1985. Recent developments in the diagnosis and treatment of sleep disorders. doi:10.1176/ps.36.9.951 PubMed
124. [124] E Hartmann et al.. Psychopharmacology (Berl). 1983. Chronic insomnia: effects of tryptophan, flurazepam, secobarbital, and placebo. doi:10.1007/BF00427957 PubMed
125. [125] M Sallanon et al.. C R Seances Acad Sci III. 1983. [Implication of hypothalamic structures in indolaminergic mechanisms of paradoxical sleep]. PubMed
126. [126] M Sallanon et al.. Eur J Pharmacol. 1982. 5-HT antagonists suppress sleep and delay its restoration after 5-HTP in p-chlorophenylalanine-pretreated cats. doi:10.1016/0014-2999(82)90549-0 PubMed
127. [127] A A Borbély et al.. Behav Brain Res. 1981. Effect of p-chlorophenylalanine and tryptophan on sleep, EEG and motor activity in the rat. doi:10.1016/0166-4328(81)90035-8 PubMed
128. [128] P K Gillman et al.. J Neurochem. 1981. Indolic substances in plasma, cerebrospinal fluid, and frontal cortex of human subjects infused with saline or tryptophan. doi:10.1111/j.1471-4159.1981.tb00470.x PubMed
129. [129] F Petitjean et al.. C R Seances Acad Sci D. 1980. [Insomnia induced by P-chlorophenylalanine in cats. Its reversibility by intraventricular injections of indolamines]. PubMed
130. [130] M Linnoila et al.. Int Pharmacopsychiatry. 1980. Efficacy and side effects of chloral hydrate and tryptophan as sleeping aids in psychogeriatric patients. doi:10.1159/000468423 PubMed
131. [131] R B Holman et al.. Annu Rev Med. 1975. Neuroregulators and sleep mechanisms. doi:10.1146/annurev.me.26.020175.002435 PubMed