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Taurine 用于 失眠

B 证据 至少一项随机试验支持这一结论,结果基本一致。

基于11项研究(1项荟萃分析),共32名参与者。各研究结果不一致。

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B

结论

基于11项研究(1项荟萃分析),共32名参与者。各研究结果不一致。

Key Study Findings

basic science
Lactobacillus reuteri E9 Regulates Sleep Disorders Through Its Metabolite GABA.
Dose: Lactobacillus reuteri E9 (dose not specified) vs: Placebo 效果: None < 0.05
Controlled Clinical Trial n=32 12 weeks Open-label
Efficacy and associated neurotransmitters of digital cognitive behavior therapy for atopic dermatitis: A comparative effectiveness …
Dose: None vs: Standard care alone Outcome: Itch and insomnia improvement in atopic dermatitis 效果: None 0.0449 (itch), 0.0089 (insomni

研究人群: Patients with atopic dermatitis and mild-moderate negative emotions

Review
Commonly encountered symptoms and their management in patients with cirrhosis.
Dose: None vs: None Outcome: Pain outcomes 效果: None None

研究人群: Insomnia patients

Other
Energy drinks in Tamale: Understanding youth perceptions, consumption patterns, and related factors.
Dose: None vs: None Outcome: None 效果: None p < .05

研究人群: Insomnia patients

Observational Study
[Energy drink consumption patterns and its adverse effects on adolescent health.].
Dose: None vs: None Outcome: Energy drink consumption and adverse effects 效果: None None

研究人群: Adolescents

Other
[Establishment of rat heart-kidney insomnia model consistent with traditional Chinese medicine syndrome and its serum …
Dose: None vs: None Outcome: rat model of cardiorenal insomnia from in vitro … 效果: None None

研究人群: None

Key Statistics

11

研究数量

32

受试者

Mixed

B

等级

Referenced Papers

British journal of … 2014 111 次引用
Alcohol and alcoholism … 2011 40 次引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

常用剂量

sleep:
500-2,000 mg, 1 hour before bed

上限: 3,000 mg/day considered safe in clinical studies

研究中使用的剂量

剂量 持续时间 效果 N
Lactobacillus reuteri E9 (dose not specified) -- Positive --
None 12 weeks Positive 32
None -- Neutral --
None -- Neutral --
None -- Mixed --
None -- Mixed --
None -- Positive --
None -- Positive --

最佳服用时间: 1 hour before bed

Safety & Side Effects

已报告的副作用

  • Generally well tolerated
  • Mild GI discomfort at high doses
  • Drowsiness (desired for sleep use)

已知相互作用

  • Lithium — taurine may alter lithium excretion
  • Antihypertensives — may have additive blood pressure lowering effects
  • CNS depressants — potential additive sedative effects

可耐受最高摄入量: 3,000 mg/day considered safe in clinical studies

在开始服用任何补充剂之前,请务必咨询您的医疗保健提供者。

Frequently Asked Questions

Does Taurine help with 失眠?
Based on 11 studies with 32 participants, there is moderate evidence from clinical studies that Taurine may support 失眠 management. Our evidence grade is B (Good Evidence).
How much Taurine should I take for 失眠?
Studies have used various dosages. A commonly studied range is 500-2,000 mg, 1 hour before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Taurine?
Reported side effects may include Generally well tolerated, Mild GI discomfort at high doses, Drowsiness (desired for sleep use). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Taurine and 失眠?
We rate the evidence as Grade B (Good Evidence). This rating is based on 11 peer-reviewed studies with 32 total participants. The overall direction of effect is mixed.

References

  1. [1] Liuyan Zhu et al.. Biomedicines. 2026. Serum Amino Acid and Fatty Acid Metabolites as Predictors of Sleep Disorders in Children: A Risk Prediction Model. doi:10.3390/biomedicines14030546 PubMed
  2. [2] Wanying Zhai et al.. Asian Pac J Allergy Immunol. 2025. Efficacy and associated neurotransmitters of digital cognitive behavior therapy for atopic dermatitis: A comparative effectiveness research. doi:10.12932/AP-100223-1542 PubMed
  3. [3] Yongcheng Jiang et al.. Front Biosci (Landmark Ed). 2025. Lactobacillus reuteri E9 Regulates Sleep Disorders Through Its Metabolite GABA. doi:10.31083/FBL39587 PubMed
  4. [4] Williams Kobik et al.. PLoS One. 2024. Energy drinks in Tamale: Understanding youth perceptions, consumption patterns, and related factors. doi:10.1371/journal.pone.0289391 PubMed
  5. [5] Cyriac Abby Philips. Front Med (Lausanne). 2024. Commonly encountered symptoms and their management in patients with cirrhosis. doi:10.3389/fmed.2024.1442525 PubMed
  6. [6] Paola Silva Maldonado et al.. Rev Esp Salud Publica. 2022. [Energy drink consumption patterns and its adverse effects on adolescent health.]. PubMed
  7. [7] Yu-Han Yang et al.. Zhongguo Zhong Yao Za Zhi. 2020. [Establishment of rat heart-kidney insomnia model consistent with traditional Chinese medicine syndrome and its serum metabolomics]. doi:10.19540/j.cnki.cjcmm.20190524.502 PubMed
  8. [8] Kirk J Brower. Alcohol. 2015. Assessment and treatment of insomnia in adult patients with alcohol use disorders. doi:10.1016/j.alcohol.2014.12.003 PubMed
  9. [9] Nicola J Kalk et al.. Br J Clin Pharmacol. 2014. The clinical pharmacology of acamprosate. doi:10.1111/bcp.12070 PubMed
  10. [10] Bhanu Prakash Kolla et al.. Alcohol Alcohol. 2011. Pharmacological treatment of insomnia in alcohol recovery: a systematic review. doi:10.1093/alcalc/agr073 PubMed
  11. [11] Kevin A Clauson et al.. J Am Pharm Assoc (2003). 2008. Safety issues associated with commercially available energy drinks. doi:10.1331/JAPhA.2008.07055 PubMed
  12. [12] Atsushi Takeda et al.. Nutr Neurosci. 2008. Suppressive effect of Yokukansan on excessive release of glutamate and aspartate in the hippocampus of zinc-deficient rats. doi:10.1179/147683008X301414 PubMed

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