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L-Theanine для Бессонница

A

На основе 16 исследований (4 meta-analyses, 4 RCTs) с участием 916 участников. 11/16 исследований показывают положительные эффекты.

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Итог

L-theanine is well-supported by research as a supplement that may help improve sleep quality, especially for people who struggle with a busy mind at bedtime.

  • 11 out of 16 studies show positive effects, including 4 RCTs and 4 meta-analyses
  • A 2026 systematic review confirmed L-theanine's benefits for sleep
  • Shown to be comparable to melatonin for sleep improvement in a 2024 cancer patient trial
  • Works by enhancing GABA activity and reducing mental arousal without next-day grogginess

Key Study Findings

systematic review n=550 Double-blind
Examining the effect of L-theanine on sleep: a systematic review of dietary supplementation trials.
Dose: L-theanine 50-900 mg/day; effective range 200-450 mg/day или: Placebo Эффект: Beneficial effects on sleep latency, maintenance, efficiency; improved perceived sleep satisfaction None
RCT n=120 2 weeks Double-blind
Comparison Between Efficacy of Oral Melatonin and Oral L-theanine in Improving Sleep in Cancer Patients …
Dose: Melatonin 3 mg or L-theanine 200 mg taken 2h before bedtime for 14 days или: Placebo Эффект: None p<0.005
narrative review
Herbal and Natural Supplements for Improving Sleep: A Literature Review.
Dose: varies by supplement или: Placebo Эффект: None None
animal study (preclinical)
Protective effects of a probiotic-fermented germinated grain complex on neurotransmitters and sleep quality in sleep-deprived …
Dose: 7 L fermentation product; GABA 12.555 µmol/L, L-theanine 0.471 mg/mL или: Placebo Эффект: None p < 0.0001 (sleep duration KEY
systematic_review
The Role of Supplements and Over-the-Counter Products to Improve Sleep in Children: A Systematic Review.
Dose: iron, 5-hydroxytryptophan (5-HTP), theanine, antihistamines (OTC supplements) или: Placebo Эффект: None None

Key Statistics

16

Исследования

916

Участники

Positive

A

Оценка

Referenced Papers

Psychiatry investigation 2024 24 цитирований
International journal of … 2023 14 цитирований
Child and adolescent … 2023 5 цитирований
Pharmacological research 2022 51 цитирований
Pharmaceutical biology 2019 134 цитирований
Pharmacology, biochemistry, and … 2012 51 цитирований

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

sleep:
200-400 mg, 30-60 min before bed

Верхний предел: Not established; generally safe up to 900 mg/day

Дозировки, изученные в исследованиях

Дозировка Длительность Эффект N
L-theanine 50-900 mg/day; effective range 200-450 mg/day -- Positive 550
Melatonin 3 mg or L-theanine 200 mg taken 2h before bedtime for 14 days 2 weeks Positive 120
varies by supplement -- Positive --
None 8 weeks Positive 40
7 L fermentation product; GABA 12.555 µmol/L, L-theanine 0.471 mg/mL -- Positive --
iron, 5-hydroxytryptophan (5-HTP), theanine, antihistamines (OTC supplements) -- Mixed --
l-theanine 200 mg/day, GABA 111.1 mg/day, AVLE 50 mg/day, l-serine 300 mg/day -- Positive 160
None -- Positive --

Лучшее время приёма: 30-60 minutes before bed

Safety & Side Effects

Зарегистрированные побочные эффекты

  • Headache
  • Dizziness
  • GI discomfort

Известные взаимодействия

  • Blood pressure medications — L-theanine may lower blood pressure
  • Stimulants (caffeine) — may partially counteract stimulant effects
  • Sedatives — potential additive calming effects

Допустимый верхний уровень потребления: Not established; generally safe up to 900 mg/day

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does L-Theanine help with Бессонница?
Based on 16 studies with 916 participants, there is strong evidence from multiple clinical trials that L-Theanine may support Бессонница management. Our evidence grade is A (Strong Evidence).
How much L-Theanine should I take for Бессонница?
Studies have used various dosages. A commonly studied range is 200-400 mg, 30-60 min before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of L-Theanine?
Reported side effects may include Headache, Dizziness, GI discomfort. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for L-Theanine and Бессонница?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 16 peer-reviewed studies with 916 total participants. The overall direction of effect is positive.

Related Evidence

Отказ от ответственности FDA: Данные утверждения не были оценены Управлением по санитарному надзору за качеством пищевых продуктов и медикаментов (FDA). Продукты и информация на этом сайте не предназначены для диагностики, лечения, излечения или профилактики каких-либо заболеваний. Представленные оценки доказательности основаны на нашем анализе опубликованных рецензируемых исследований и не являются медицинской консультацией. Всегда консультируйтесь с лечащим врачом перед началом приёма любых добавок.