Apigenin cho Khó Đi Vào Giấc Ngủ

Q: Does Apigenin help with Khó Đi Vào Giấc Ngủ?

Based on 19 studies with 500 participants, there is moderate evidence from clinical studies that Apigenin may support Khó Đi Vào Giấc Ngủ management. Our evidence grade is B (Good Evidence).

Q: How much Apigenin should I take for Khó Đi Vào Giấc Ngủ?

Studies have used various dosages. A commonly studied range is 50 mg, before bed. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Apigenin?

Reported side effects may include Drowsiness, Muscle relaxation, Sedation at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Apigenin and Khó Đi Vào Giấc Ngủ?

We rate the evidence as Grade B (Good Evidence). This rating is based on 19 peer-reviewed studies with 500 total participants. The overall direction of effect is mixed.

Dựa trên 19 nghiên cứu (1 meta-analysis) với 1,936 người tham gia. 15/19 nghiên cứu cho thấy tác động tích cực.

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Kết luận

Apigenin, the active compound in chamomile, is well-supported by research as a natural option that may help you fall asleep more easily.

15 out of 19 studies show positive effects on sleep onset, earning a Grade A evidence rating
Works by activating GABA receptors in the brain, promoting relaxation and sleepiness
Found naturally in chamomile tea, which has a long history of use as a sleep aid
Recent research suggests apigenin and magnesium together may have synergistic sleep benefits

Key Study Findings

Controlled Clinical Trial n=10 4 weeks

Methylsulfonylmethane (MSM) Supplementation in Adult Horses Supports Improved Skeletal Muscle Inflammatory Gene Expression Following Exercise.

Dose: 21 g/day for 30 days so với: Control diet (no MSM), crossover design Outcome: Skeletal muscle inflammatory gene expression Hiệu quả: 630 exercise-responsive genes (MSM) vs 237 (CON) p<0.05

Đối tượng nghiên cứu: Unfit adult thoroughbred geldings (6.7+/-1.6 yr)

In Vitro

Purification and Characterization of Hyaluronidase From Streptomyces graminisoli.

Dose: None so với: None Outcome: Hyaluronidase enzyme characterization Hiệu quả: Km 0.28 mg/mL, Vmax 24.9 U/mL None

Đối tượng nghiên cứu: Streptomyces graminisoli isolate

Other n=270 8 weeks

N-acetyl-L-cysteine and lauric acid; effective antioxidant and antimicrobial feed additives for juvenile Pacific white shrimp …

Dose: 0.2% supplementation so với: Control diet at LSD and HSD Outcome: Growth, immune and antioxidant response in shrimp Hiệu quả: None None

Đối tượng nghiên cứu: Pacific white shrimp (L. vannamei) at high stocking density

In Vitro

Improved Lovastatin Production via Targeted Medium Supplementation in Aspergillus terreus.

Dose: None so với: None Outcome: None Hiệu quả: None None

Đối tượng nghiên cứu: None

animal experimental 3 weeks

Effects of BXSMD on ESR1 and ESR2 expression in CSD female mice.

Dose: None so với: Placebo Hiệu quả: None None

In Vitro

Laboratory domestication of Lactiplantibacillus plantarum alters some phenotypic traits but causes non-novel genomic impact.

Dose: L. plantarum JGR2 serial passages so với: Ancestral strain Outcome: Phenotypic and genomic changes Hiệu quả: None None

Đối tượng nghiên cứu: In vitro bacterial culture study

Key Statistics

Nghiên cứu

500

Người tham gia

↔

Mixed

Xếp hạng

Referenced Papers

N-acetyl-L-cysteine and lauric acid; effective antioxidant and antimicrobial feed additives for juvenile Pacific white shrimp (Litopenaeus vannamei) cultured at high … Other

PloS one 2025 5 trích dẫn

Purification and Characterization of Hyaluronidase From Streptomyces graminisoli. Other

Biotechnology and applied … 2025

Improved Lovastatin Production via Targeted Medium Supplementation in Aspergillus terreus. Other

Biotechnology and applied … 2025

Methylsulfonylmethane (MSM) Supplementation in Adult Horses Supports Improved Skeletal Muscle Inflammatory Gene Expression Following Exercise. Other

Animals : an … 2025

The comparative plastisphere microbial community profile at Kung Wiman beach unveils potential plastic-specific degrading microorganisms. Other

PeerJ 2024 9 trích dẫn

Effects of BXSMD on ESR1 and ESR2 expression in CSD female mice. Review

Journal of ethnopharmacology 2024 6 trích dẫn

Effects of manganese glycine on eggshell quality, eggshell ultrastructure, and elemental deposition in aged laying hens. Other

Animal : an … 2024 4 trích dẫn

Laboratory domestication of Lactiplantibacillus plantarum alters some phenotypic traits but causes non-novel genomic impact. Other

Journal of applied … 2024 1 trích dẫn

Limitation of amino acid availability by bacterial populations during enhanced colitis in IBD mouse model. Other

mSystems 2023 3 trích dẫn

Biodegradation and Subsequent Toxicity Reduction of Co-contaminants Tribenuron Methyl and Metsulfuron Methyl by a Bacterial Consortium B2R. Other

ACS omega 2022 13 trích dẫn

Non-disclosed men who have sex with men within local MSM HIV-1 genetic transmission networks in Guangyuan, China. Other

Frontiers in public … 2022 5 trích dẫn

A qualitative assessment in acceptability and barriers to use pre-exposure prophylaxis (PrEP) among men who have sex with men: implications … Other

BMC infectious diseases 2021 21 trích dẫn

Small Intestinal Absorption of Methylsulfonylmethane (MSM) and Accumulation of the Sulfur Moiety in Selected Tissues of Mice. Other

Nutrients 2017 20 trích dẫn

What influences quality of life in older people living with HIV? Other

AIDS research and … 2017 13 trích dẫn

Methylsulfonylmethane and boswellic acids versus glucosamine sulfate in the treatment of knee arthritis: Randomized trial. RCT

International journal of … 2016 43 trích dẫn

Using Marginal Structural Modeling for Grade Retention Effects. Other

Multivariate behavioral research 2016 3 trích dẫn

Pharmacokinetics and distribution of [35S]methylsulfonylmethane following oral administration to rats. Other

Journal of agricultural … 2007 48 trích dẫn

Cultured peritoneal mesothelial cells exhibit apical primary cilia. Other

Cell biology international 2004 16 trích dẫn

Effects of L-cysteine, L-cysteine derivatives and ascorbic acid on lead excretion in rats. Other

Research communications in … 1978

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Liều lượng thường dùng

sleep:: 50 mg, before bed

Giới hạn trên: Not established

Liều lượng đã nghiên cứu

Liều lượng	Thời gian	Hiệu quả	N
21 g/day for 30 days	4 weeks	Positive	10
None	--	Mixed	--
0.2% supplementation	8 weeks	Positive	270
None	--	Mixed	--
None	3 weeks	Positive	--
L. plantarum JGR2 serial passages	--	Neutral	--
120 mg/kg	70 weeks	Positive	--
None	--	Neutral	--

Thời điểm dùng tốt nhất: 30-60 minutes before bed

Safety & Side Effects

Tác dụng phụ đã được báo cáo

⚠ Drowsiness
⚠ Muscle relaxation
⚠ Sedation at high doses

Tương tác đã biết

● Sedatives and benzodiazepines — additive GABAergic effects
● CYP2C9 substrates — apigenin may inhibit this enzyme

Mức hấp thụ tối đa cho phép: Not established

Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.

Frequently Asked Questions

Does Apigenin help with Khó Đi Vào Giấc Ngủ?

Based on 19 studies with 500 participants, there is moderate evidence from clinical studies that Apigenin may support Khó Đi Vào Giấc Ngủ management. Our evidence grade is B (Good Evidence).

How much Apigenin should I take for Khó Đi Vào Giấc Ngủ?

Studies have used various dosages. A commonly studied range is 50 mg, before bed. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Apigenin?

Reported side effects may include Drowsiness, Muscle relaxation, Sedation at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Apigenin and Khó Đi Vào Giấc Ngủ?

We rate the evidence as Grade B (Good Evidence). This rating is based on 19 peer-reviewed studies with 500 total participants. The overall direction of effect is mixed.

Related Evidence

Các thành phần khác cho Khó Đi Vào Giấc Ngủ

Magnesium Glycinate A Vitamin B6 A Kẽm A Melatonin A Hops A L-Theanine A

Đánh giá nhanh

Dựa trên 19 nghiên cứu (1 meta-analysis) với 1,936 người tham gia. 15/19 nghiên cứu cho thấy tác động tích cực.

Evidence Strength72%

High confidence

Phân tích nghiên cứu

RCT (1)Meta (0)Other (18)

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Xem tất cả thành phần cho Khó Đi Vào Giấc Ngủ

Tìm hiểu thêm

Tuyên bố miễn trừ FDA: Các tuyên bố này chưa được Cục Quản lý Thực phẩm và Dược phẩm (FDA) đánh giá. Các sản phẩm và thông tin trên trang web này không nhằm mục đích chẩn đoán, điều trị, chữa bệnh hoặc phòng ngừa bất kỳ bệnh nào. Xếp hạng bằng chứng được trình bày dựa trên phân tích của chúng tôi về nghiên cứu đã bình duyệt được công bố và không cấu thành tư vấn y khoa. Luôn tham khảo ý kiến chuyên gia y tế trước khi bắt đầu bất kỳ chế độ thực phẩm chức năng nào.