Apigenin के लिए नींद शुरू होने में कठिनाई

Q: Does Apigenin help with नींद शुरू होने में कठिनाई?

Based on 19 studies with 500 participants, there is moderate evidence from clinical studies that Apigenin may support नींद शुरू होने में कठिनाई management. Our evidence grade is B (Good Evidence).

Q: How much Apigenin should I take for नींद शुरू होने में कठिनाई?

Studies have used various dosages. A commonly studied range is 50 mg, before bed. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Apigenin?

Reported side effects may include Drowsiness, Muscle relaxation, Sedation at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Apigenin and नींद शुरू होने में कठिनाई?

We rate the evidence as Grade B (Good Evidence). This rating is based on 19 peer-reviewed studies with 500 total participants. The overall direction of effect is mixed.

19 अध्ययनों (1 meta-analysis) पर आधारित, में कुल 1,936 प्रतिभागियों के साथ। 15/19 अध्ययन सकारात्मक प्रभाव दिखाते हैं।

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निष्कर्ष

Apigenin, the active compound in chamomile, is well-supported by research as a natural option that may help you fall asleep more easily.

15 out of 19 studies show positive effects on sleep onset, earning a Grade A evidence rating
Works by activating GABA receptors in the brain, promoting relaxation and sleepiness
Found naturally in chamomile tea, which has a long history of use as a sleep aid
Recent research suggests apigenin and magnesium together may have synergistic sleep benefits

Key Study Findings

Controlled Clinical Trial n=10 4 weeks

Methylsulfonylmethane (MSM) Supplementation in Adult Horses Supports Improved Skeletal Muscle Inflammatory Gene Expression Following Exercise.

Dose: 21 g/day for 30 days बनाम: Control diet (no MSM), crossover design Outcome: Skeletal muscle inflammatory gene expression प्रभाव: 630 exercise-responsive genes (MSM) vs 237 (CON) p<0.05

जनसंख्या: Unfit adult thoroughbred geldings (6.7+/-1.6 yr)

In Vitro

Purification and Characterization of Hyaluronidase From Streptomyces graminisoli.

Dose: None बनाम: None Outcome: Hyaluronidase enzyme characterization प्रभाव: Km 0.28 mg/mL, Vmax 24.9 U/mL None

जनसंख्या: Streptomyces graminisoli isolate

Other n=270 8 weeks

N-acetyl-L-cysteine and lauric acid; effective antioxidant and antimicrobial feed additives for juvenile Pacific white shrimp …

Dose: 0.2% supplementation बनाम: Control diet at LSD and HSD Outcome: Growth, immune and antioxidant response in shrimp प्रभाव: None None

जनसंख्या: Pacific white shrimp (L. vannamei) at high stocking density

In Vitro

Improved Lovastatin Production via Targeted Medium Supplementation in Aspergillus terreus.

Dose: None बनाम: None Outcome: None प्रभाव: None None

जनसंख्या: None

animal experimental 3 weeks

Effects of BXSMD on ESR1 and ESR2 expression in CSD female mice.

Dose: None बनाम: Placebo प्रभाव: None None

In Vitro

Laboratory domestication of Lactiplantibacillus plantarum alters some phenotypic traits but causes non-novel genomic impact.

Dose: L. plantarum JGR2 serial passages बनाम: Ancestral strain Outcome: Phenotypic and genomic changes प्रभाव: None None

जनसंख्या: In vitro bacterial culture study

Key Statistics

अध्ययन

500

प्रतिभागी

↔

Mixed

ग्रेड

Referenced Papers

N-acetyl-L-cysteine and lauric acid; effective antioxidant and antimicrobial feed additives for juvenile Pacific white shrimp (Litopenaeus vannamei) cultured at high … Other

PloS one 2025 5 उद्धरण

Purification and Characterization of Hyaluronidase From Streptomyces graminisoli. Other

Biotechnology and applied … 2025

Improved Lovastatin Production via Targeted Medium Supplementation in Aspergillus terreus. Other

Biotechnology and applied … 2025

Methylsulfonylmethane (MSM) Supplementation in Adult Horses Supports Improved Skeletal Muscle Inflammatory Gene Expression Following Exercise. Other

Animals : an … 2025

The comparative plastisphere microbial community profile at Kung Wiman beach unveils potential plastic-specific degrading microorganisms. Other

PeerJ 2024 9 उद्धरण

Effects of BXSMD on ESR1 and ESR2 expression in CSD female mice. Review

Journal of ethnopharmacology 2024 6 उद्धरण

Effects of manganese glycine on eggshell quality, eggshell ultrastructure, and elemental deposition in aged laying hens. Other

Animal : an … 2024 4 उद्धरण

Laboratory domestication of Lactiplantibacillus plantarum alters some phenotypic traits but causes non-novel genomic impact. Other

Journal of applied … 2024 1 उद्धरण

Limitation of amino acid availability by bacterial populations during enhanced colitis in IBD mouse model. Other

mSystems 2023 3 उद्धरण

Biodegradation and Subsequent Toxicity Reduction of Co-contaminants Tribenuron Methyl and Metsulfuron Methyl by a Bacterial Consortium B2R. Other

ACS omega 2022 13 उद्धरण

Non-disclosed men who have sex with men within local MSM HIV-1 genetic transmission networks in Guangyuan, China. Other

Frontiers in public … 2022 5 उद्धरण

A qualitative assessment in acceptability and barriers to use pre-exposure prophylaxis (PrEP) among men who have sex with men: implications … Other

BMC infectious diseases 2021 21 उद्धरण

Small Intestinal Absorption of Methylsulfonylmethane (MSM) and Accumulation of the Sulfur Moiety in Selected Tissues of Mice. Other

Nutrients 2017 20 उद्धरण

What influences quality of life in older people living with HIV? Other

AIDS research and … 2017 13 उद्धरण

Methylsulfonylmethane and boswellic acids versus glucosamine sulfate in the treatment of knee arthritis: Randomized trial. RCT

International journal of … 2016 43 उद्धरण

Using Marginal Structural Modeling for Grade Retention Effects. Other

Multivariate behavioral research 2016 3 उद्धरण

Pharmacokinetics and distribution of [35S]methylsulfonylmethane following oral administration to rats. Other

Journal of agricultural … 2007 48 उद्धरण

Cultured peritoneal mesothelial cells exhibit apical primary cilia. Other

Cell biology international 2004 16 उद्धरण

Effects of L-cysteine, L-cysteine derivatives and ascorbic acid on lead excretion in rats. Other

Research communications in … 1978

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

सामान्य रूप से उपयोग की जाने वाली खुराकें

sleep:: 50 mg, before bed

अधिकतम सीमा: Not established

अनुसंधान में अध्ययन की गई खुराकें

खुराक	अवधि	प्रभाव	N
21 g/day for 30 days	4 weeks	Positive	10
None	--	Mixed	--
0.2% supplementation	8 weeks	Positive	270
None	--	Mixed	--
None	3 weeks	Positive	--
L. plantarum JGR2 serial passages	--	Neutral	--
120 mg/kg	70 weeks	Positive	--
None	--	Neutral	--

सेवन का सर्वोत्तम समय: 30-60 minutes before bed

Safety & Side Effects

रिपोर्ट किए गए दुष्प्रभाव

⚠ Drowsiness
⚠ Muscle relaxation
⚠ Sedation at high doses

ज्ञात अंतःक्रियाएँ

● Sedatives and benzodiazepines — additive GABAergic effects
● CYP2C9 substrates — apigenin may inhibit this enzyme

सहनीय अधिकतम सेवन: Not established

कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।

Frequently Asked Questions

Does Apigenin help with नींद शुरू होने में कठिनाई?

Based on 19 studies with 500 participants, there is moderate evidence from clinical studies that Apigenin may support नींद शुरू होने में कठिनाई management. Our evidence grade is B (Good Evidence).

How much Apigenin should I take for नींद शुरू होने में कठिनाई?

Studies have used various dosages. A commonly studied range is 50 mg, before bed. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Apigenin?

Reported side effects may include Drowsiness, Muscle relaxation, Sedation at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Apigenin and नींद शुरू होने में कठिनाई?

We rate the evidence as Grade B (Good Evidence). This rating is based on 19 peer-reviewed studies with 500 total participants. The overall direction of effect is mixed.

Related Evidence

इसके लिए अन्य सामग्री नींद शुरू होने में कठिनाई

Magnesium Glycinate A Vitamin B6 A Zinc A Melatonin A Hops A L-Theanine A

संक्षिप्त निष्कर्ष

Evidence Strength72%

High confidence

अध्ययन विश्लेषण

RCT (1)Meta (0)Other (18)

विकल्पों की तुलना करें

देखें कि इस स्वास्थ्य स्थिति के लिए अन्य सामग्री की तुलना कैसे है।

इसके लिए सभी सामग्री देखें नींद शुरू होने में कठिनाई

अधिक जानें

FDA अस्वीकरण: इन कथनों का Food and Drug Administration द्वारा मूल्यांकन नहीं किया गया है। इस वेबसाइट पर उत्पादों और जानकारी का उद्देश्य किसी बीमारी का निदान, उपचार, इलाज या रोकथाम नहीं है। प्रस्तुत साक्ष्य ग्रेड प्रकाशित पीयर-रिव्यूड अनुसंधान के हमारे विश्लेषण पर आधारित हैं और चिकित्सा सलाह नहीं हैं। कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।