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Ashwagandha cho Khó Đi Vào Giấc Ngủ

B

Dựa trên 6 nghiên cứu (3 RCTs) với 454 người tham gia. 6/6 nghiên cứu cho thấy tác động tích cực.

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B

Kết luận

Research suggests ashwagandha may help you fall asleep faster, with multiple well-designed clinical trials consistently showing reduced time to fall asleep.

  • All 6 studies show positive effects, including 3 RCTs with 454 total participants
  • A 2024 meta-analysis confirmed benefits for sleep onset
  • Active compound triethylene glycol from ashwagandha leaves has been identified as a sleep-inducing agent
  • Benefits observed in both healthy adults and people diagnosed with insomnia

Key Study Findings

systematic review and meta-analysis n=254
Safety and efficacy of Withania somnifera for anxiety and insomnia: Systematic review and meta-analysis.
Dose: varies across included RCTs so với: Placebo Hiệu quả: HAM-A MD = -5.96 (95% CI -10.34, -1.59); significant improvements in SOL, TST, PSQI, SE; no signific 0.008 (HAM-A)
animal_study
Hydroalcoholic Extract of Ashwagandha Improves Sleep by Modulating GABA/Histamine Receptors and EEG Slow-Wave Pattern in …
Dose: 10, 25, or 50 mg/kg body weight ashwagandha extract (AE, 35% withanolide glycosides, Shoden) so với: Placebo Hiệu quả: At 50 mg/kg: 34% decrease in sleep onset time (p<0.0001); 47% increase in sleep duration (p<0.0001); <0.0001
Randomized Controlled Trial n=80 8 weeks Double-blind
Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers …
Dose: None so với: Placebo Hiệu quả: None SOL p=0.013; HAM-A p<0.05; men
RCT n=60 4 weeks Open-label
Efficacy of Brimhana Nasya and Ashwagandha (Withania somnifera (L.) Dunal) root powder in primary insomnia …
Dose: None so với: Placebo Hiệu quả: None p<0.0001
Randomized Controlled Trial n=60 10 weeks Double-blind
Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, …
Dose: 300 mg twice daily so với: Placebo Hiệu quả: SOL: 29.00 vs 33.94 min (placebo) at 10 weeks; SE: 83.48 vs 79.68 p=0.019 (SOL); p=0.002 (sleep
In Vitro
Triethylene glycol, an active component of Ashwagandha (Withania somnifera) leaves, is responsible for sleep induction.
Dose: 10-30 mg/mouse (triethylene glycol); water extract of Ashwagandha leaves so với: Placebo Hiệu quả: Significant increase in NREM sleep in a dose-dependent manner None

Key Statistics

6

Nghiên cứu

454

Người tham gia

Positive

B

Xếp hạng

Referenced Papers

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Liều lượng thường dùng

sleep:
300-600 mg KSM-66 or Sensoril, before bed

Giới hạn trên: Not established; studied up to 1,200 mg/day

Liều lượng đã nghiên cứu

Liều lượng Thời gian Hiệu quả N
varies across included RCTs -- Positive 254
10, 25, or 50 mg/kg body weight ashwagandha extract (AE, 35% withanolide glycosides, Shoden) -- Positive --
None 8 weeks Positive 80
None 4 weeks Positive 60
300 mg twice daily 10 weeks Positive 60
10-30 mg/mouse (triethylene glycol); water extract of Ashwagandha leaves -- Positive --

Thời điểm dùng tốt nhất: 1-2 hours before bed

Safety & Side Effects

Tác dụng phụ đã được báo cáo

  • Drowsiness
  • GI upset
  • Diarrhea
  • Headache

Tương tác đã biết

  • Thyroid medications — ashwagandha may increase thyroid hormone levels
  • Immunosuppressants — ashwagandha may stimulate immune activity
  • Sedatives — potential additive drowsiness
  • Blood sugar medications — may lower blood glucose

Mức hấp thụ tối đa cho phép: Not established; studied up to 1,200 mg/day

Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.

Frequently Asked Questions

Does Ashwagandha help with Khó Đi Vào Giấc Ngủ?
Based on 6 studies with 454 participants, there is moderate evidence from clinical studies that Ashwagandha may support Khó Đi Vào Giấc Ngủ management. Our evidence grade is B (Good Evidence).
How much Ashwagandha should I take for Khó Đi Vào Giấc Ngủ?
Studies have used various dosages. A commonly studied range is 300-600 mg KSM-66 or Sensoril, before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Ashwagandha?
Reported side effects may include Drowsiness, GI upset, Diarrhea, Headache. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Ashwagandha and Khó Đi Vào Giấc Ngủ?
We rate the evidence as Grade B (Good Evidence). This rating is based on 6 peer-reviewed studies with 454 total participants. The overall direction of effect is positive.

Related Evidence

Ashwagandha cho các tình trạng khác

Tuyên bố miễn trừ FDA: Các tuyên bố này chưa được Cục Quản lý Thực phẩm và Dược phẩm (FDA) đánh giá. Các sản phẩm và thông tin trên trang web này không nhằm mục đích chẩn đoán, điều trị, chữa bệnh hoặc phòng ngừa bất kỳ bệnh nào. Xếp hạng bằng chứng được trình bày dựa trên phân tích của chúng tôi về nghiên cứu đã bình duyệt được công bố và không cấu thành tư vấn y khoa. Luôn tham khảo ý kiến chuyên gia y tế trước khi bắt đầu bất kỳ chế độ thực phẩm chức năng nào.