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Ashwagandha pour Difficulté d'Endormissement

B

Basé sur 6 études (3 RCTs) avec 454 participants au total. 6/6 études montrent des effets positifs.

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B

En conclusion

Research suggests ashwagandha may help you fall asleep faster, with multiple well-designed clinical trials consistently showing reduced time to fall asleep.

  • All 6 studies show positive effects, including 3 RCTs with 454 total participants
  • A 2024 meta-analysis confirmed benefits for sleep onset
  • Active compound triethylene glycol from ashwagandha leaves has been identified as a sleep-inducing agent
  • Benefits observed in both healthy adults and people diagnosed with insomnia

Key Study Findings

systematic review and meta-analysis n=254
Safety and efficacy of Withania somnifera for anxiety and insomnia: Systematic review and meta-analysis.
Dose: varies across included RCTs vs: Placebo Effet: HAM-A MD = -5.96 (95% CI -10.34, -1.59); significant improvements in SOL, TST, PSQI, SE; no signific 0.008 (HAM-A)
animal_study
Hydroalcoholic Extract of Ashwagandha Improves Sleep by Modulating GABA/Histamine Receptors and EEG Slow-Wave Pattern in …
Dose: 10, 25, or 50 mg/kg body weight ashwagandha extract (AE, 35% withanolide glycosides, Shoden) vs: Placebo Effet: At 50 mg/kg: 34% decrease in sleep onset time (p<0.0001); 47% increase in sleep duration (p<0.0001); <0.0001
Randomized Controlled Trial n=80 8 weeks Double-blind
Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers …
Dose: None vs: Placebo Effet: None SOL p=0.013; HAM-A p<0.05; men
Randomized Controlled Trial n=60 10 weeks Double-blind
Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, …
Dose: 300 mg twice daily vs: Placebo Effet: SOL: 29.00 vs 33.94 min (placebo) at 10 weeks; SE: 83.48 vs 79.68 p=0.019 (SOL); p=0.002 (sleep
In Vitro
Triethylene glycol, an active component of Ashwagandha (Withania somnifera) leaves, is responsible for sleep induction.
Dose: 10-30 mg/mouse (triethylene glycol); water extract of Ashwagandha leaves vs: Placebo Effet: Significant increase in NREM sleep in a dose-dependent manner None

Key Statistics

6

Études

454

Participants

Positive

B

Note

Referenced Papers

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Posologies couramment utilisées

sleep:
300-600 mg KSM-66 or Sensoril, before bed

Limite supérieure : Not established; studied up to 1,200 mg/day

Posologies étudiées dans la recherche

Posologie Durée Effet N
varies across included RCTs -- Positive 254
10, 25, or 50 mg/kg body weight ashwagandha extract (AE, 35% withanolide glycosides, Shoden) -- Positive --
None 8 weeks Positive 80
None 4 weeks Positive 60
300 mg twice daily 10 weeks Positive 60
10-30 mg/mouse (triethylene glycol); water extract of Ashwagandha leaves -- Positive --

Moment optimal de prise : 1-2 hours before bed

Safety & Side Effects

Effets indésirables signalés

  • Drowsiness
  • GI upset
  • Diarrhea
  • Headache

Interactions connues

  • Thyroid medications — ashwagandha may increase thyroid hormone levels
  • Immunosuppressants — ashwagandha may stimulate immune activity
  • Sedatives — potential additive drowsiness
  • Blood sugar medications — may lower blood glucose

Apport maximal tolérable : Not established; studied up to 1,200 mg/day

Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.

Frequently Asked Questions

Does Ashwagandha help with Difficulté d'Endormissement?
Based on 6 studies with 454 participants, there is moderate evidence from clinical studies that Ashwagandha may support Difficulté d'Endormissement management. Our evidence grade is B (Good Evidence).
How much Ashwagandha should I take for Difficulté d'Endormissement?
Studies have used various dosages. A commonly studied range is 300-600 mg KSM-66 or Sensoril, before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Ashwagandha?
Reported side effects may include Drowsiness, GI upset, Diarrhea, Headache. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Ashwagandha and Difficulté d'Endormissement?
We rate the evidence as Grade B (Good Evidence). This rating is based on 6 peer-reviewed studies with 454 total participants. The overall direction of effect is positive.

Related Evidence

Avertissement FDA: Ces déclarations n'ont pas été évaluées par la Food and Drug Administration. Les produits et informations sur ce site ne sont pas destinés à diagnostiquer, traiter, guérir ou prévenir quelque maladie que ce soit. Les notes de preuve présentées sont basées sur notre analyse de la recherche publiée et évaluée par des pairs et ne constituent pas un avis médical. Consultez toujours votre professionnel de santé avant de commencer tout régime de compléments alimentaires.