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Ashwagandha için Uykuya Dalma Güçlüğü

B

6 çalışmaya (3 RCTs), toplam 454 katılımcıyla dayanmaktadır. 6/6 çalışma olumlu etkiler göstermektedir.

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B

Sonuç

Research suggests ashwagandha may help you fall asleep faster, with multiple well-designed clinical trials consistently showing reduced time to fall asleep.

  • All 6 studies show positive effects, including 3 RCTs with 454 total participants
  • A 2024 meta-analysis confirmed benefits for sleep onset
  • Active compound triethylene glycol from ashwagandha leaves has been identified as a sleep-inducing agent
  • Benefits observed in both healthy adults and people diagnosed with insomnia

Key Study Findings

systematic review and meta-analysis n=254
Safety and efficacy of Withania somnifera for anxiety and insomnia: Systematic review and meta-analysis.
Dose: varies across included RCTs vs: Placebo Etki: HAM-A MD = -5.96 (95% CI -10.34, -1.59); significant improvements in SOL, TST, PSQI, SE; no signific 0.008 (HAM-A)
animal_study
Hydroalcoholic Extract of Ashwagandha Improves Sleep by Modulating GABA/Histamine Receptors and EEG Slow-Wave Pattern in …
Dose: 10, 25, or 50 mg/kg body weight ashwagandha extract (AE, 35% withanolide glycosides, Shoden) vs: Placebo Etki: At 50 mg/kg: 34% decrease in sleep onset time (p<0.0001); 47% increase in sleep duration (p<0.0001); <0.0001
Randomized Controlled Trial n=80 8 weeks Double-blind
Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers …
Dose: None vs: Placebo Etki: None SOL p=0.013; HAM-A p<0.05; men
Randomized Controlled Trial n=60 10 weeks Double-blind
Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, …
Dose: 300 mg twice daily vs: Placebo Etki: SOL: 29.00 vs 33.94 min (placebo) at 10 weeks; SE: 83.48 vs 79.68 p=0.019 (SOL); p=0.002 (sleep
In Vitro
Triethylene glycol, an active component of Ashwagandha (Withania somnifera) leaves, is responsible for sleep induction.
Dose: 10-30 mg/mouse (triethylene glycol); water extract of Ashwagandha leaves vs: Placebo Etki: Significant increase in NREM sleep in a dose-dependent manner None

Key Statistics

6

Çalışmalar

454

Katılımcılar

Positive

B

Derece

Referenced Papers

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Yaygın Kullanılan Dozajlar

sleep:
300-600 mg KSM-66 or Sensoril, before bed

Üst sınır: Not established; studied up to 1,200 mg/day

Araştırmalarda İncelenen Dozajlar

Dozaj Süre Etki N
varies across included RCTs -- Positive 254
10, 25, or 50 mg/kg body weight ashwagandha extract (AE, 35% withanolide glycosides, Shoden) -- Positive --
None 8 weeks Positive 80
None 4 weeks Positive 60
300 mg twice daily 10 weeks Positive 60
10-30 mg/mouse (triethylene glycol); water extract of Ashwagandha leaves -- Positive --

En iyi alım zamanı: 1-2 hours before bed

Safety & Side Effects

Bildirilen Yan Etkiler

  • Drowsiness
  • GI upset
  • Diarrhea
  • Headache

Bilinen Etkileşimler

  • Thyroid medications — ashwagandha may increase thyroid hormone levels
  • Immunosuppressants — ashwagandha may stimulate immune activity
  • Sedatives — potential additive drowsiness
  • Blood sugar medications — may lower blood glucose

Tolere edilebilir üst alım: Not established; studied up to 1,200 mg/day

Herhangi bir takviye kullanmaya başlamadan önce mutlaka sağlık uzmanınıza danışın.Herhangi bir takviye başlatmadan önce her zaman sağlık uzmanınıza danışın.

Frequently Asked Questions

Does Ashwagandha help with Uykuya Dalma Güçlüğü?
Based on 6 studies with 454 participants, there is moderate evidence from clinical studies that Ashwagandha may support Uykuya Dalma Güçlüğü management. Our evidence grade is B (Good Evidence).
How much Ashwagandha should I take for Uykuya Dalma Güçlüğü?
Studies have used various dosages. A commonly studied range is 300-600 mg KSM-66 or Sensoril, before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Ashwagandha?
Reported side effects may include Drowsiness, GI upset, Diarrhea, Headache. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Ashwagandha and Uykuya Dalma Güçlüğü?
We rate the evidence as Grade B (Good Evidence). This rating is based on 6 peer-reviewed studies with 454 total participants. The overall direction of effect is positive.

Related Evidence

Şu durum için diğer içerikler: Uykuya Dalma Güçlüğü

Ashwagandha diğer sağlık durumları için

FDA Sorumluluk Reddi: Bu ifadeler Gıda ve İlaç Dairesi (FDA) tarafından değerlendirilmemiştir. Bu web sitesindeki ürünler ve bilgiler herhangi bir hastalığı teşhis etmek, tedavi etmek, iyileştirmek veya önlemek amacıyla tasarlanmamıştır. Sunulan kanıt dereceleri, yayımlanmış hakemli araştırmalarımızın analizine dayanmaktadır ve tıbbi tavsiye niteliği taşımamaktadır. Herhangi bir takviye rejimine başlamadan önce her zaman sağlık uzmanınıza danışın.